Tempus AI Launches Clinical Test xH
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 5 hours ago
0mins
Tempus AI announced the upcoming clinical availability of xH, a next-generation sequencing, NGS, test that uses a whole-genome sequencing, WGS, approach for the detection of actionable oncologic targets in peripheral blood and bone marrow samples from patients with hematologic malignancies. "When we introduced xH, our goal was to create a standardized WGS platform that could transform care in hematologic oncology," said Tom Schonherr, CEO of Diagnostics, at Tempus. "We've realized that vision by replacing multiple time-consuming diagnostic tests with a single, high-throughput whole-genome workflow that helps clinicians make faster, smarter decisions. At the same time, xH provides biopharma partners with a comprehensive multiomic foundation to improve clinical trial design, accelerate biomarker discovery, and support the development of next-generation targeted therapies."
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Analyst Views on TEM
Wall Street analysts forecast TEM stock price to rise
9 Analyst Rating
4 Buy
5 Hold
0 Sell
Moderate Buy
Current: 50.470
Low
76.00
Averages
84.38
High
105.00
Current: 50.470
Low
76.00
Averages
84.38
High
105.00
About TEM
Tempus AI, Inc. is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare. It offers AI-enabled precision medicine solutions to physicians to deliver personalized patient care and, in parallel, facilitates discovery, development and delivery of optimal therapeutics. It provides three product lines: Genomics, Data and artificial intelligence applications (AI). The Genomics product line leverages its laboratories to provide next generation sequencing (NGS) diagnostics, polymerase chain reaction, profiling, molecular genotyping and other anatomic and molecular pathology testing. The data generated in its lab or ingested into its platform is structured and de-identified, prior to commercialization. Its AI Applications is focused on developing and providing diagnostics that are algorithmic in nature, implementing new software as a medical device, and building and deploying clinical decision support tools.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Tempus AI Launches Next-Generation Genetic Test for Oncology
- Clinical Availability Boost: Tempus AI announces the upcoming launch of the xH test, which utilizes whole-genome sequencing to detect actionable oncologic targets in blood and bone marrow samples, expected to significantly enhance diagnostic efficiency for patients with hematologic malignancies.
- Validation Study Results: In an analytical validation study involving 235 unique specimens, the xH test achieved a positive percent agreement of 97.29% for SNVs and Indels, demonstrating high accuracy across multiple variant classes and bolstering confidence in its clinical application.
- Sensitivity and Discovery Rate: In a blinded study of an MDS cohort, the xH test achieved over 99% sensitivity and uncovered more than 40% of clinically relevant genomic variations that were missed by traditional methods, highlighting its superiority in guiding clinical decisions.
- Strategic Goal Achievement: Tempus CEO Tom Schonherr stated that the launch of the xH test marks the realization of the company's vision in hematologic oncology, streamlining diagnostic processes to enable faster decision-making for clinicians while providing biopharma partners with a multiomic foundation to enhance clinical trial design and targeted therapy development.
See More
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- User Base Expansion: The Lens platform is currently utilized by 19 of the top 20 biopharma companies globally, indicating its widespread recognition and application potential in the industry, further solidifying Tempus's leadership in precision medicine.
- Intelligent Analysis Tools: The new platform offers custom research plan generation and on-demand execution features, allowing users to propose complex hypotheses in natural language and quickly receive targeted analysis plans, thereby reducing clinical trial design time and improving decision-making efficiency.
- Transparency and Reproducibility: Results from the Lens platform are presented through interactive applications and reports, with users able to toggle to a
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- Innovative Challenge Program: Tempus has launched the PRECISION Challenge, aimed at accelerating breakthroughs in oncology by providing funding, data, and expertise to multidisciplinary teams worldwide, which is expected to significantly enhance cancer treatment outcomes.
- Resource Support: The program offers participants up to $75,000 in funding and computational resources to support various stages from proof of concept to clinical performance validation, ensuring that funding is closely tied to research progress.
- Data Access: Participants will gain access to Tempus' de-identified data library, one of the world's largest repositories of clinical, molecular, and imaging data, combined with Tempus' foundational models and computational infrastructure to facilitate biological discovery.
- Future Outlook: Tempus plans to open applications in the coming months, encouraging researchers to seize this unprecedented opportunity to address critical issues in oncology and advance precision medicine.
See More
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- Focus on High-Impact Biomarkers: The application targets early insights into high-impact biomarkers such as microsatellite instability (MSI-H) and EGFR mutations, enhancing predictions for responses to immune checkpoint inhibitors and targeted therapies, thereby improving patient prognosis.
- AI-Driven Precision Analysis: Powered by the Paige Predict model, Tempus Preview analyzes standard H&E images to deliver genomic insights, having been validated for clinical use after training on millions of slides, which further strengthens Tempus's competitive edge in the precision medicine sector.
- Strategic Data Integration: By combining its unique diagnostic lab with an advanced data platform, Tempus creates powerful AI models that deliver early, clinically relevant information directly into clinical workflows, assisting physicians in making more informed decisions in patient treatment.
See More
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- Model Scale: The company's latest multimodal foundation model was trained on 2.5 million longitudinal patient records, including 250 million clinical note pages, 450,000 medical images, and 500,000 genomic and transcriptomic sequences, which is expected to accelerate drug development and improve clinical trial design.
- Clinical Predictive Power: In a study involving EGFR-mutant non-small cell lung cancer patients, the model demonstrated a C-index of 0.802, indicating strong predictive accuracy and significant survival stratification across patient groups, highlighting its potential for early identification of high-risk cancer patients.
- Market Performance: Over the past five days, Tempus AI's stock has climbed approximately 10.68%, significantly outperforming the S&P 500's return of 0.66%, reflecting investor optimism regarding the demand for data-driven precision medicine.
See More
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- Data-Driven Precision Medicine: Tempus AI leverages over 500 petabytes of molecular data and 1.5 million sequenced records to build multimodal foundation models, significantly enhancing the efficiency of clinical trial design and patient risk prediction, thereby accelerating the application of precision medicine.
- Model Performance Validation: When analyzing EGFR-mutant NSCLC patients, the model achieved a C-index of 0.802, indicating high accuracy in survival predictions, with a hazard ratio of 4.536 between high- and low-risk subgroups, demonstrating significant survival stratification capabilities.
- Clinical Trial Potential: Tempus' multimodal patient trajectory model outperformed traditional Cox-PH modeling in cohorts mirroring clinical trials, indicating substantial utility in drug development by assessing features that may impact clinical trial performance before trials commence.
- Strategic Vision: Founder Eric Lefkofsky emphasized that the combination of foundation models and agentic workflows will expedite hypothesis testing and compress the timeline from discovery to clinical application, driving the development of new diagnostics and novel medicines, further solidifying the company's leadership in precision medicine.
See More
Tempus AI Launches Next-Generation Genetic Test for Oncology
- Clinical Availability Boost: Tempus AI announces the upcoming launch of the xH test, which utilizes whole-genome sequencing to detect actionable oncologic targets in blood and bone marrow samples, expected to significantly enhance diagnostic efficiency for patients with hematologic malignancies.
- Validation Study Results: In an analytical validation study involving 235 unique specimens, the xH test achieved a positive percent agreement of 97.29% for SNVs and Indels, demonstrating high accuracy across multiple variant classes and bolstering confidence in its clinical application.
- Sensitivity and Discovery Rate: In a blinded study of an MDS cohort, the xH test achieved over 99% sensitivity and uncovered more than 40% of clinically relevant genomic variations that were missed by traditional methods, highlighting its superiority in guiding clinical decisions.
- Strategic Goal Achievement: Tempus CEO Tom Schonherr stated that the launch of the xH test marks the realization of the company's vision in hematologic oncology, streamlining diagnostic processes to enable faster decision-making for clinicians while providing biopharma partners with a multiomic foundation to enhance clinical trial design and targeted therapy development.
See More
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- Platform Upgrade: The next-generation Lens platform launched by Tempus integrates over a decade of real-world data and AI tools, aiming to accelerate drug development and significantly enhance research efficiency for biopharma companies.
- User Base Expansion: The Lens platform is currently utilized by 19 of the top 20 biopharma companies globally, indicating its widespread recognition and application potential in the industry, further solidifying Tempus's leadership in precision medicine.
- Intelligent Analysis Tools: The new platform offers custom research plan generation and on-demand execution features, allowing users to propose complex hypotheses in natural language and quickly receive targeted analysis plans, thereby reducing clinical trial design time and improving decision-making efficiency.
- Transparency and Reproducibility: Results from the Lens platform are presented through interactive applications and reports, with users able to toggle to a
See More
Tempus Launches PRECISION Challenge to Accelerate Oncology Breakthroughs
- Innovative Challenge Program: Tempus has launched the PRECISION Challenge, aimed at accelerating breakthroughs in oncology by providing funding, data, and expertise to multidisciplinary teams worldwide, which is expected to significantly enhance cancer treatment outcomes.
- Resource Support: The program offers participants up to $75,000 in funding and computational resources to support various stages from proof of concept to clinical performance validation, ensuring that funding is closely tied to research progress.
- Data Access: Participants will gain access to Tempus' de-identified data library, one of the world's largest repositories of clinical, molecular, and imaging data, combined with Tempus' foundational models and computational infrastructure to facilitate biological discovery.
- Future Outlook: Tempus plans to open applications in the coming months, encouraging researchers to seize this unprecedented opportunity to address critical issues in oncology and advance precision medicine.
See More
Tempus AI Launches Rapid Clinical Insights Application
- Breakthrough in Precision Medicine: Tempus AI's newly launched Tempus Preview application provides key mutation predictions within approximately 24 hours of tissue receipt, significantly reducing the time between diagnostic test orders and final results, enabling faster treatment decisions during the critical early stages following a cancer diagnosis.
- Focus on High-Impact Biomarkers: The application targets early insights into high-impact biomarkers such as microsatellite instability (MSI-H) and EGFR mutations, enhancing predictions for responses to immune checkpoint inhibitors and targeted therapies, thereby improving patient prognosis.
- AI-Driven Precision Analysis: Powered by the Paige Predict model, Tempus Preview analyzes standard H&E images to deliver genomic insights, having been validated for clinical use after training on millions of slides, which further strengthens Tempus's competitive edge in the precision medicine sector.
- Strategic Data Integration: By combining its unique diagnostic lab with an advanced data platform, Tempus creates powerful AI models that deliver early, clinically relevant information directly into clinical workflows, assisting physicians in making more informed decisions in patient treatment.
See More
Tempus AI Unveils New AI-Driven Precision Medicine Data
- Stock Surge: Tempus AI (TEM) saw its stock jump over 3% to approximately $53.15 after unveiling new AI-driven precision medicine data at the 2026 ASCO Annual Meeting, indicating strong market enthusiasm for its technological advancements.
- Model Scale: The company's latest multimodal foundation model was trained on 2.5 million longitudinal patient records, including 250 million clinical note pages, 450,000 medical images, and 500,000 genomic and transcriptomic sequences, which is expected to accelerate drug development and improve clinical trial design.
- Clinical Predictive Power: In a study involving EGFR-mutant non-small cell lung cancer patients, the model demonstrated a C-index of 0.802, indicating strong predictive accuracy and significant survival stratification across patient groups, highlighting its potential for early identification of high-risk cancer patients.
- Market Performance: Over the past five days, Tempus AI's stock has climbed approximately 10.68%, significantly outperforming the S&P 500's return of 0.66%, reflecting investor optimism regarding the demand for data-driven precision medicine.
See More
Tempus AI Unveils Latest Results on Multimodal Foundation Models
- Data-Driven Precision Medicine: Tempus AI leverages over 500 petabytes of molecular data and 1.5 million sequenced records to build multimodal foundation models, significantly enhancing the efficiency of clinical trial design and patient risk prediction, thereby accelerating the application of precision medicine.
- Model Performance Validation: When analyzing EGFR-mutant NSCLC patients, the model achieved a C-index of 0.802, indicating high accuracy in survival predictions, with a hazard ratio of 4.536 between high- and low-risk subgroups, demonstrating significant survival stratification capabilities.
- Clinical Trial Potential: Tempus' multimodal patient trajectory model outperformed traditional Cox-PH modeling in cohorts mirroring clinical trials, indicating substantial utility in drug development by assessing features that may impact clinical trial performance before trials commence.
- Strategic Vision: Founder Eric Lefkofsky emphasized that the combination of foundation models and agentic workflows will expedite hypothesis testing and compress the timeline from discovery to clinical application, driving the development of new diagnostics and novel medicines, further solidifying the company's leadership in precision medicine.
See More
