Silence Therapeutics Presents Additional Phase 1 Data Highlighting Promise of Divesiran as the Potential First-in-Class siRNA Treatment for Polycythemia Vera
Divesiran Phase 1 Study Results: Updated data from the SANRECO Phase 1 study presented at the EHA 2025 Annual Meeting shows that divesiran effectively maintains hematocrit levels in patients with polycythemia vera, significantly reducing the need for phlebotomies while demonstrating a favorable safety profile.
SANRECO Phase 2 Study Progress: Silence Therapeutics announced that the SANRECO Phase 2 study of divesiran has surpassed 50% enrollment and is on track for full enrollment by the end of 2025, indicating strong support from the medical community for this first-in-class siRNA therapy.
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Bausch Health's Gradual Recovery Under Increased Scrutiny Following Lombard Odier's Stake Reduction
Lombard Odier's Stake Reduction: Lombard Odier Asset Management (USA) Corp sold 3,334,000 shares of Bausch Health Companies, reducing its position by approximately $22.56 million, which now represents 0.74% of the fund's assets.
Bausch Health's Financial Struggles: Bausch Health Companies has faced a decline in share price, down 24.6% over the past year, raising concerns about its ability to manage heavy debt and ongoing legal liabilities.
Investor Sentiment: The reduction in Lombard Odier's stake suggests a shift in investor confidence, indicating that while there may still be potential upside, the fund no longer holds the same level of conviction in Bausch Health's recovery.
Future Outlook: The company's ability to improve its cash generation and manage its capital structure will be crucial for its long-term potential, as it seeks to avoid asset sales that could undermine its equity case.
Monday's Underperformers: Auto Dealerships and Biotechnology Shares
Biotechnology Sector Performance: Biotechnology shares are down approximately 2.1% on Monday, with notable declines from Emergent BioSolutions and Silence Therapeutics, which fell by 15.4% and 8.1%, respectively.
Market Context: The decline in biotechnology stocks is part of a broader market trend, with auto dealerships also lagging behind on the same day.
Source Disclaimer: The views expressed in the article are those of the author and do not necessarily represent the opinions of Nasdaq, Inc.
Video Content: A video segment highlights the sector laggards, specifically focusing on auto dealerships and biotechnology stocks.
HC Wainwright & Co. Affirms Buy Rating for Silence Therapeutics, Keeps $75 Price Target Intact
Real-time Intelligence: Benzinga Pro offers the fastest news alerts to help traders stay informed and make winning trades in the stock market.
Exclusive Community: Joining Benzinga Pro connects users with over 10,000 serious traders and provides access to exclusive stories and insights from Benzinga reporters.
Silence Therapeutics Reports Second Quarter 2025 Financial Results and Recent Business Highlights
Divesiran Development: Silence Therapeutics presented promising data on divesiran as a first-in-class siRNA for Polycythemia Vera (PV) at the EHA 2025, showing effective hematocrit control and minimal need for phlebotomies, with Phase 2 trial enrollment expected to complete by year-end 2025.
Financial Overview: The company reported a net loss of $27.4 million for Q2 2025, with cash reserves of approximately $114.2 million projected to fund operations through 2028, while R&D expenses increased due to advancing clinical trials.
Silence Therapeutics Presents Additional Phase 1 Data Highlighting Promise of Divesiran as the Potential First-in-Class siRNA Treatment for Polycythemia Vera
Divesiran Phase 1 Study Results: Updated data from the SANRECO Phase 1 study presented at the EHA 2025 Annual Meeting shows that divesiran effectively maintains hematocrit levels in patients with polycythemia vera, significantly reducing the need for phlebotomies while demonstrating a favorable safety profile.
SANRECO Phase 2 Study Progress: Silence Therapeutics announced that the SANRECO Phase 2 study of divesiran has surpassed 50% enrollment and is on track for full enrollment by the end of 2025, indicating strong support from the medical community for this first-in-class siRNA therapy.
Chardan Capital Maintains Buy on Silence Therapeutics, Lowers Price Target to $35
Real-time Intelligence for Traders: Benzinga Pro offers the fastest news alerts and exclusive stories to help traders make informed decisions in the stock market.
Community of Serious Traders: Over 10,000 traders are part of the Benzinga Pro community, benefiting from accurate market intelligence and insights.
Bausch Health's Gradual Recovery Under Increased Scrutiny Following Lombard Odier's Stake Reduction
Lombard Odier's Stake Reduction: Lombard Odier Asset Management (USA) Corp sold 3,334,000 shares of Bausch Health Companies, reducing its position by approximately $22.56 million, which now represents 0.74% of the fund's assets.
Bausch Health's Financial Struggles: Bausch Health Companies has faced a decline in share price, down 24.6% over the past year, raising concerns about its ability to manage heavy debt and ongoing legal liabilities.
Investor Sentiment: The reduction in Lombard Odier's stake suggests a shift in investor confidence, indicating that while there may still be potential upside, the fund no longer holds the same level of conviction in Bausch Health's recovery.
Future Outlook: The company's ability to improve its cash generation and manage its capital structure will be crucial for its long-term potential, as it seeks to avoid asset sales that could undermine its equity case.
Monday's Underperformers: Auto Dealerships and Biotechnology Shares
Biotechnology Sector Performance: Biotechnology shares are down approximately 2.1% on Monday, with notable declines from Emergent BioSolutions and Silence Therapeutics, which fell by 15.4% and 8.1%, respectively.
Market Context: The decline in biotechnology stocks is part of a broader market trend, with auto dealerships also lagging behind on the same day.
Source Disclaimer: The views expressed in the article are those of the author and do not necessarily represent the opinions of Nasdaq, Inc.
Video Content: A video segment highlights the sector laggards, specifically focusing on auto dealerships and biotechnology stocks.
HC Wainwright & Co. Affirms Buy Rating for Silence Therapeutics, Keeps $75 Price Target Intact
Real-time Intelligence: Benzinga Pro offers the fastest news alerts to help traders stay informed and make winning trades in the stock market.
Exclusive Community: Joining Benzinga Pro connects users with over 10,000 serious traders and provides access to exclusive stories and insights from Benzinga reporters.
Silence Therapeutics Reports Second Quarter 2025 Financial Results and Recent Business Highlights
Divesiran Development: Silence Therapeutics presented promising data on divesiran as a first-in-class siRNA for Polycythemia Vera (PV) at the EHA 2025, showing effective hematocrit control and minimal need for phlebotomies, with Phase 2 trial enrollment expected to complete by year-end 2025.
Financial Overview: The company reported a net loss of $27.4 million for Q2 2025, with cash reserves of approximately $114.2 million projected to fund operations through 2028, while R&D expenses increased due to advancing clinical trials.
Silence Therapeutics Presents Additional Phase 1 Data Highlighting Promise of Divesiran as the Potential First-in-Class siRNA Treatment for Polycythemia Vera
Divesiran Phase 1 Study Results: Updated data from the SANRECO Phase 1 study presented at the EHA 2025 Annual Meeting shows that divesiran effectively maintains hematocrit levels in patients with polycythemia vera, significantly reducing the need for phlebotomies while demonstrating a favorable safety profile.
SANRECO Phase 2 Study Progress: Silence Therapeutics announced that the SANRECO Phase 2 study of divesiran has surpassed 50% enrollment and is on track for full enrollment by the end of 2025, indicating strong support from the medical community for this first-in-class siRNA therapy.
Chardan Capital Maintains Buy on Silence Therapeutics, Lowers Price Target to $35
Real-time Intelligence for Traders: Benzinga Pro offers the fastest news alerts and exclusive stories to help traders make informed decisions in the stock market.
Community of Serious Traders: Over 10,000 traders are part of the Benzinga Pro community, benefiting from accurate market intelligence and insights.
