Significant Options Trading on Wednesday: AMGN, SD, JNJ
SandRidge Energy Options Activity: SandRidge Energy Inc (SD) has seen a trading volume of 1,383 options contracts today, equating to about 138,300 underlying shares, which is 51.6% of its average daily trading volume over the past month.
High Volume Call Option for SandRidge: The $15 strike call option expiring on April 17, 2026, has particularly high activity with 764 contracts traded, representing approximately 76,400 underlying shares.
Johnson & Johnson Options Activity: Johnson & Johnson (JNJ) reported an options trading volume of 38,997 contracts today, which corresponds to around 3.9 million underlying shares, or 51% of its average daily trading volume over the past month.
High Volume Call Option for Johnson & Johnson: The $175 strike call option expiring on November 21, 2025, has seen significant trading with 3,133 contracts, representing about 313,300 underlying shares.
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Eli Lilly Reaches $950 Billion Market Cap as GLP-1 Drug Leader
- Market Leadership: Eli Lilly has become the world's most valuable healthcare company with a market cap of approximately $950 billion, having seen its stock price soar 400% over the past five years, primarily driven by the popularity of its GLP-1 drugs, Mounjaro and Zepbound, indicating strong market demand and growth potential.
- New Drug Development Outlook: Amgen is developing a GLP-1 drug called MariTide, which offers a once-monthly injection treatment option that may appeal to patients preferring reduced injection frequency, thereby expanding its market share.
- Clinical Trial Results: In clinical trials, MariTide has demonstrated the ability to help patients lose up to 20% of their body weight over a 52-week period, comparable to existing GLP-1 treatments, highlighting its competitive edge in the weight loss market.
- Investment Value Analysis: Amgen's stock currently trades at a forward P/E ratio of 16, significantly lower than Eli Lilly's 32, indicating its relative undervaluation; if MariTide gains approval, the stock price could see substantial upside, making it an attractive investment opportunity.

Eli Lilly vs Amgen: Stock Comparison Insights
- Valuation Discrepancy: Eli Lilly trades at over 30 times forward earnings with a market cap of approximately $950 billion, having seen a 400% stock price increase over the past five years, indicating strong performance in the GLP-1 drug market, yet its high valuation may pose risks for investors.
- Amgen's Potential: Amgen's GLP-1 drug MariTide is currently in phase 3 trials and may help patients lose up to 20% of their body weight over 52 weeks, with a forward P/E of just 16, suggesting a lower investment threshold and significant upside potential.
- Market Outlook: The GLP-1 drug market is projected to exceed $150 billion within the next decade, providing opportunities for companies like Eli Lilly and Amgen to capture substantial market share in this rapidly growing sector, attracting investor interest.
- Cautious Investment Advice: Despite MariTide's promising clinical results, analysts note that Amgen is not included in the current list of top investment stocks, urging investors to carefully assess potential risks and rewards before making investment decisions.






