Cellectis announces Q3 adjusted EPS of 2 cents compared to a loss of 22 cents in the previous year.
Q3 Revenue Growth: Cellectis reported a Q3 revenue of $35.17 million, a significant increase from $16.2 million in the previous year.
Clinical Program Success: CEO Andre Choulika highlighted promising data from their lasme-cel and eti-cel programs, indicating potential improvements in treating high unmet medical needs in r/r B-ALL and r/r NHL.
Upcoming Milestones: Cellectis plans to share further updates on the eti-cel program at the ASH 2025 Annual Meeting and expects to provide the first interim analysis for the pivotal Phase 2 BALLI-01 trial in Q4 2026.
Leadership in CAR-T Innovation: These developments are positioned to strengthen Cellectis's leadership in allogeneic CAR-T innovation, setting the stage for a transformative year ahead.
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Cellectis Initiates Pivotal Trials for Lasme-cel and Eti-cel, 2026 Outlook Positive
- Clinical Trial Progress: Cellectis initiated the pivotal Phase 2 BALLI-01 trial for lasme-cel in October 2025, with the first interim analysis expected in Q4 2026 involving 40 participants, showcasing the company's strong growth potential in tumor immunotherapy.
- Impressive Efficacy Data: Lasme-cel achieved a 100% overall response rate and a 56% complete remission rate in the target Phase 2 population, with 80% of patients reaching minimal residual disease-negative status, indicating significant efficacy in treating relapsed acute lymphoblastic leukemia (B-ALL).
- Deepening Strategic Partnerships: Cellectis is advancing its collaboration with AstraZeneca to develop up to 10 novel cell and gene therapy products addressing high unmet medical needs, further solidifying its leadership position in the biotechnology sector.
- Sufficient Cash Runway: Cellectis believes its cash and cash equivalents will fund operations into H2 2027, ensuring continued progress in critical clinical trials and strategic investments.

Autolus Evaluates Cellares' Automated Platform for Manufacturing Expansion
- Manufacturing Capability Assessment: Autolus will evaluate Cellares' Cell Shuttle platform to enhance its commercial manufacturing operations at the Nucleus facility in Stevenage, UK, which is expected to improve production efficiency and reduce costs.
- High-Throughput Production: Cellares' platform can process up to 16 patient batches simultaneously, delivering up to 10-fold higher throughput than conventional cell therapy manufacturing facilities, potentially significantly enhancing Autolus' market competitiveness.
- Exploration of New Indications: Autolus is assessing its AUCATZYL® therapy for indications beyond acute lymphoblastic leukemia, and successful expansion could lead to increased demand for manufacturing capacity.
- Strategic Partnership Outlook: The integration of Cellares' technology with Autolus' existing manufacturing foundation may provide a capital-efficient solution for future expansion, addressing the growing patient demand.









