Penumbra Reports 90-Day Results of STORM-PE Trial
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 2 days ago
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Should l Buy PEN?
Source: PRnewswire
- Clinical Trial Results: Penumbra's STORM-PE trial revealed that patients with acute intermediate-high risk pulmonary embolism treated with computer-assisted vacuum thrombectomy (CAVT™) plus anticoagulation showed significant functional improvements at 90 days, including increased walking distance and a higher proportion achieving NYHA Class I, indicating the substantial clinical potential of CAVT.
- Safety Confirmation: Over the 90-day observation period, safety rates were comparable between the CAVT and anticoagulation groups, with no device-related mortality and no significant differences in PE-related mortality after 7 days, further validating the safety profile of CAVT and supporting its clinical application.
- Evolving Treatment Strategies: The results from the STORM-PE trial underscore the importance of CAVT in treating intermediate-high risk pulmonary embolism, potentially leading to a shift in future clinical guidelines towards broader adoption of endovascular treatment options, thereby improving patient recovery and quality of life.
- Future Research Directions: The upcoming STRIKE-PE study, set to present on April 15, will provide long-term quality-of-life and functional outcome data for CAVT in male and female pulmonary embolism patients, further validating the clinical efficacy of CAVT and advancing the treatment landscape for pulmonary embolism.
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Analyst Views on PEN
Wall Street analysts forecast PEN stock price to rise
15 Analyst Rating
14 Buy
1 Hold
0 Sell
Strong Buy
Current: 332.170
Low
266.00
Averages
344.64
High
388.00
Current: 332.170
Low
266.00
Averages
344.64
High
388.00
About PEN
Penumbra, Inc. is a thrombectomy company, which is focused on developing technologies for challenging medical conditions, such as ischemic stroke, venous thromboembolism, such as pulmonary embolism, and acute limb ischemia. The Company's broad portfolio, which includes computer assisted vacuum thrombectomy (CAVT), centers on removing blood clots from head-to-toe. It focuses on developing, manufacturing and marketing novel products for use by specialist physicians and healthcare providers to drive improved clinical and health outcomes. Some of the conditions it focuses on are Pulmonary Embolism, Deep Vein Thrombosis, Acute Limb Ischemia, Ischemic Stroke, Acute Coronary Syndrome, and Clot associated with Arteriovenous Graft or Fistula. The Company sells its products to healthcare providers primarily through its direct sales organization in the United States, Europe, Canada and Australia, as well as through distributors in select international markets.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Clinical Trial Results: Penumbra's STORM-PE trial revealed that patients with acute intermediate-high risk pulmonary embolism treated with computer-assisted vacuum thrombectomy (CAVT™) plus anticoagulation showed significant functional improvements at 90 days, including increased walking distance and a higher proportion achieving NYHA Class I, indicating the substantial clinical potential of CAVT.
- Safety Confirmation: Over the 90-day observation period, safety rates were comparable between the CAVT and anticoagulation groups, with no device-related mortality and no significant differences in PE-related mortality after 7 days, further validating the safety profile of CAVT and supporting its clinical application.
- Evolving Treatment Strategies: The results from the STORM-PE trial underscore the importance of CAVT in treating intermediate-high risk pulmonary embolism, potentially leading to a shift in future clinical guidelines towards broader adoption of endovascular treatment options, thereby improving patient recovery and quality of life.
- Future Research Directions: The upcoming STRIKE-PE study, set to present on April 15, will provide long-term quality-of-life and functional outcome data for CAVT in male and female pulmonary embolism patients, further validating the clinical efficacy of CAVT and advancing the treatment landscape for pulmonary embolism.
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