Nasdaq Drops More Than 150 Points; Disney Stock Declines Following Q4 Earnings Report
Market Performance: U.S. stocks opened lower, with the Nasdaq Composite dropping over 150 points, while the Dow and S&P 500 also experienced declines. Energy shares rose by 0.6%, but communication services stocks fell by 1.2%.
Walt Disney Co. Earnings: Disney's shares fell approximately 5% after reporting fiscal Q4 2025 results, with adjusted EPS of $1.11 beating estimates, but revenue remained flat at $22.5 billion, missing analyst forecasts.
Notable Stock Movements: Mersana Therapeutics saw a 207% increase in shares after announcing an acquisition, while Korro Bio's shares plummeted 79% following disappointing financial results and a decision to wind down R&D activities.
Global Market Trends: European shares were mixed, with the eurozone's STOXX 600 down 0.2%, while Asian markets closed higher, led by gains in Japan's Nikkei 225 and Hong Kong's Hang Seng.
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Korro Bio's KRRO-121 Receives Strong Analyst Upgrades
- Analyst Upgrades: H.C. Wainwright upgraded Korro Bio to ‘Buy’ from ‘Neutral’ with a $20 price target, asserting that KRRO-121 serves as an independently risk-mitigated asset, thereby enhancing market confidence in the stock.
- Stock Price Surge: Shares of Korro Bio jumped 13% on Thursday following optimistic upgrades from multiple analysts, indicating strong market confidence in the new drug development candidate KRRO-121, which is likely to attract more investor interest.
- Clinical Trial Plans: Korro intends to file for clinical trials of KRRO-121 in the second half of 2026, targeting hyperammonemia treatment, which could present new growth opportunities for the company in addressing this critical metabolic condition.
- Market Sentiment Shift: Retail sentiment on Stocktwits for KRRO stock shifted from ‘bearish’ to ‘extremely bullish’ in the past 24 hours, with message volume increasing from ‘high’ to ‘extremely high’, reflecting strong optimism among investors regarding the company’s prospects.

Wall Street Analysts Adjust Ratings
- Analyst Rating Updates: Top Wall Street analysts have adjusted their ratings on several companies, reflecting a shift in market sentiment that could influence investor decisions and market trends.
- Overview of Changes: The rating changes include upgrades, downgrades, and new initiations, providing investors with a comprehensive view of market analysis to better seize investment opportunities.
- Investor Attention: The changes in analyst ratings may draw investor interest towards FTNT stock, particularly in the current market environment where investors need to closely monitor these shifts for informed decision-making.
- Market Impact Assessment: Analyst rating adjustments not only affect the performance of individual stocks but can also influence overall market sentiment, prompting investors to consider these factors to optimize their investment portfolios.









