Most Active Stocks in Pre-Market on November 3, 2025: CRBU, CURR, KVUE, CIFR, IREN, BITF, TSLL, FUBO, BMY, PFE, HKD, PCG
NASDAQ 100 Pre-Market Performance: The NASDAQ 100 Pre-Market Indicator is up 190.14 points to 26,048.27, with a total pre-market volume of 273,604,382 shares traded.
Active Stocks Overview: Caribou Biosciences, Inc. (CRBU) leads with significant trading volume and is set to report earnings on 11/5/2025, while other active stocks include Currenc Group Inc. (CURR), Kenvue Inc. (KVUE), and Cipher Mining Inc. (CIFR), all showing positive price movements.
Earnings Forecasts: Several companies, including Bristol-Myers Squibb (BMY) and Pfizer, are scheduled to report earnings soon, with forecasts indicating significant increases in earnings per share compared to the previous year.
Market Recommendations: Stocks like Bitfarms Ltd. (BITF) and PG&E Corp (PCG) are currently rated in the "buy range" according to Zacks, indicating positive market sentiment.
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Trump Administration Launches Medicare Drug Price Negotiations
- Expansion of Drug Negotiations: The Trump administration has expanded Medicare drug price negotiations to include treatments administered in doctors' offices for conditions such as diabetes and HIV, affecting 15 drugs set to take effect in 2028, aiming to reduce out-of-pocket costs for beneficiaries.
- Spending Overview: According to the Centers for Medicare and Medicaid Services, approximately 1.8 million beneficiaries utilized these medications between 2024 and 2025, accounting for about $27 billion in spending, highlighting the significance of Medicare expenditures in drug price negotiations.
- Pharmaceutical Impact Assessment: Analysts indicate that for 14 of the drugs, only Gilead's Biktarvy significantly impacts the company's estimated 2027 global sales, representing around 8%, while other drugs' Medicare revenue exposure is limited to 0% to 3%, suggesting minimal overall revenue impact for pharmaceutical companies.
- Kaiser Settlement on Fraud: Kaiser Permanente has agreed to a historic $556 million settlement over Medicare Advantage fraud allegations, reflecting the government's stringent enforcement stance on Medicare fraud, which could have far-reaching implications for the industry.

Wall Street Analysts Adjust Ratings
- Analyst Rating Updates: Top Wall Street analysts have adjusted their ratings on several companies, reflecting varying market perspectives on their outlooks, which could influence investor decisions.
- Market Reaction Insight: While specific rating changes are not detailed, analysts' opinions typically have a direct impact on stock prices, prompting investors to closely monitor these shifts.
- Investor Guidance: When considering the purchase of GM stock, analysts' insights may provide crucial reference points, aiding investors in making more informed investment choices.
- Source of Rating Changes: Comprehensive information on all analyst rating changes can be found on the analyst ratings page, ensuring investors stay updated with the latest market insights.









