MediWound and Vericel Sign $197M Contract
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Apr 02 2026
0mins
MediWound (MDWD) announced that Vericel (VCEL), its exclusive distributor of NexoBrid in North America, has been awarded a ten-year contract valued at up to $197M by the U.S. Biomedical Advanced Research and Development Authority, part of the Administration for Strategic Preparedness and Response within the U.S. Department of Health and Human Services. Vericel reported that the contract is for the procurement of NexoBrid, establishment and maintenance of a Vendor Managed Inventory system, design and validation of a U.S.-based manufacturing facility, and the development of a next generation formulation and additional indication for NexoBrid. Vericel further reported that the base period contract of $35M includes approximately $10M over the next 12 months for the initial procurement of NexoBrid for the U.S. Strategic National Stockpile and VMI establishment, funding for VMI-related services and initial development activities for a potential expanded NexoBrid indication for the treatment of blast trauma injuries. According to Vericel, the ten-year contract, effective as of April 1, also includes optional awards for additional NexoBrid procurement to expand the Strategic National Stockpile, further clinical development for a potential blast trauma indication, design and validation of a potential U.S.-based manufacturing facility and the development and procurement of a room temperature stable formulation of NexoBrid.
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Analyst Views on MDWD
Wall Street analysts forecast MDWD stock price to rise
6 Analyst Rating
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 14.560
Low
25.00
Averages
30.00
High
36.00
Current: 14.560
Low
25.00
Averages
30.00
High
36.00
About MDWD
Mediwound Ltd is an Israel-based biopharmaceutical company that develops, manufactures and commercializes novel, cost effective, bio-therapeutic solutions for tissue repair and regeneration. Company's portfolio is focused on next-generation protein-based therapies for burn and wound care and tissue repair and includes products such as, NexoBrid, a concentrate of proteolytic enzymes enriched in bromelain, which is an easy to use, topically-applied product that removes eschar in four hours without harming the surrounding healthy tissues.; EscharEx biological drug candidate for the debridement of chronic and other hard-to-heal wounds; MW005 a topically applied biological drug candidate for the treatment of non-melanoma skin cancers, based on the same API of NexoBrid and EscharEx products, a concentrate of proteolytic enzymes enriched in bromelain.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
MediWound Reports Q1 2026 Revenue Decline and Reaffirms Guidance
- Significant Revenue Decline: MediWound reported total revenue of $1.5 million for Q1 2026, representing a 62.5% decrease from $4 million in the same quarter last year, primarily due to reduced BARDA-related revenues and postponed shipments linked to regional conflicts, which directly impacted the company's financial performance.
- Wider Net Loss: The company reported a net loss of $3 million, or $0.23 per share, compared to a net loss of $0.7 million, or $0.07 per share, in the prior year, indicating a significant deterioration in profitability amid rising operational costs and declining revenues.
- Increased Adjusted EBITDA Loss: Adjusted EBITDA loss expanded to $7 million this quarter, up from $4 million in the same period last year, highlighting the intensified challenges the company faces in managing costs and boosting revenues.
- Full-Year Revenue Guidance Reaffirmed: MediWound reaffirmed its full-year 2026 revenue guidance, projecting revenues between $24 million and $26 million, primarily supported by expected revenues from government-related development services in the second half of 2026, demonstrating the company's confidence in future growth prospects.
See More
MediWound Advances ESCAREX Program Towards Commercialization
- New Contract Support: MediWound Ltd has signed a 10-year contract with BARDA valued at up to $197 million, aimed at supporting NexoBrid's strategic role in mass casualty burn response, thereby enhancing the company's position in the emergency medical market.
- Revenue Guidance Confirmation: The company reaffirmed its revenue guidance for 2026 at $24 million to $26 million, with expected support from government-related development services, demonstrating confidence in future revenue streams.
- Increased R&D Spending: R&D expenses rose from $2.9 million to $5.2 million in Q1 2026, reflecting ongoing investment in the ESCAREX study, although this resulted in an operating loss of $8 million, indicating short-term financial pressure.
- Market Potential Expansion: The market potential for Escorex is validated by an industry consensus document, with peak sales projections reaching $831 million from venous leg ulcers and diabetic foot ulcers, indicating a positive commercial outlook in the chronic wound care sector.
See More
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- Oversold Signal: Mediwound Ltd. (Ticker: MDWD) saw its RSI drop to 26.3 on Wednesday, indicating the stock has entered oversold territory, suggesting that the recent heavy selling pressure may be waning, thus providing potential buying opportunities for investors.
- Price Fluctuation: MDWD's stock price hit a low of $14.14 during trading, with the current trading price at $14.33, reflecting a 52-week low of $14.14 and a high of $22.505, indicating significant market volatility.
- Market Comparison: In contrast, the S&P 500 ETF (SPY) has an RSI of 74.2, highlighting MDWD's oversold condition, which may attract investors looking for low-entry opportunities in the market.
- Investor Sentiment: Despite the current low stock price, investors may view this as a favorable entry point, especially as the RSI indicates oversold conditions, potentially leading to increased buying activity.
See More
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- Earnings Beat: MediWound reported a Q1 GAAP EPS of -$0.23, surpassing expectations by $0.42, indicating resilience in profitability despite overall revenue decline.
- Significant Revenue Drop: The company’s Q1 revenue of $1.48M fell 62.6% year-over-year and missed expectations, primarily due to the timing of BARDA-related revenues and delayed shipments from regional conflicts, highlighting external challenges impacting operations.
- Full-Year Guidance Reaffirmed: MediWound reaffirmed its 2026 revenue guidance of $24 million to $26 million, with anticipated revenue from government-related development services in the second half of 2026, reflecting confidence in future growth prospects.
- Clinical Program Expansion: The company showcased its expansion plans for the EscharEx clinical programs at the European Wound Management Association (EWMA) 2026, demonstrating ongoing investment and strategic positioning in innovative treatment solutions.
See More
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- Revenue Expectations: The anticipated revenue for Q1 stands at $3.37 million, representing a 99.9% year-over-year drop, which highlights major hurdles in market competition and product sales, potentially undermining investor confidence.
- Historical Performance Review: Over the past two years, MediWound has only surpassed EPS estimates 38% of the time and revenue estimates 63% of the time, showcasing uncertainty in the company's earnings forecasts that could lead to stock price volatility.
- Estimate Revision Trends: In the last three months, EPS estimates have seen one upward revision and two downward adjustments, while revenue estimates experienced two upward and two downward revisions, indicating a divergence in analyst outlooks on the company's future performance that may impact investor decisions.
See More
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- Consensus Redefines Debridement: The U.S. multidisciplinary expert panel's consensus redefines debridement as a biologically active intervention that drives healing by reducing biofilm and bacterial burden, providing theoretical support for MediWound's EscharEx® and potentially enhancing its application in the chronic wound care market.
- Importance of Early Treatment: The consensus advocates for prioritizing effective, less invasive treatment methods when appropriate, which not only improves patient treatment experiences but may also reduce healthcare costs, thereby strengthening EscharEx®'s competitive position as a first-line debridement therapy.
- Clinical Research Support: EscharEx® has demonstrated good safety and efficacy in multiple Phase II clinical studies, enabling rapid removal of non-viable tissue and promoting granulation, laying the groundwork for its application in the upcoming Phase III VALUE trial targeting venous leg ulcers, indicating significant market potential.
- Global Market Opportunity: MediWound's innovative EscharEx® therapy for chronic wounds, which combines multiple therapeutic actions, is expected to meet the growing global demand for advanced debridement solutions, further solidifying the company's leadership position in the biotherapeutics field.
See More
MediWound Reports Q1 2026 Revenue Decline and Reaffirms Guidance
- Significant Revenue Decline: MediWound reported total revenue of $1.5 million for Q1 2026, representing a 62.5% decrease from $4 million in the same quarter last year, primarily due to reduced BARDA-related revenues and postponed shipments linked to regional conflicts, which directly impacted the company's financial performance.
- Wider Net Loss: The company reported a net loss of $3 million, or $0.23 per share, compared to a net loss of $0.7 million, or $0.07 per share, in the prior year, indicating a significant deterioration in profitability amid rising operational costs and declining revenues.
- Increased Adjusted EBITDA Loss: Adjusted EBITDA loss expanded to $7 million this quarter, up from $4 million in the same period last year, highlighting the intensified challenges the company faces in managing costs and boosting revenues.
- Full-Year Revenue Guidance Reaffirmed: MediWound reaffirmed its full-year 2026 revenue guidance, projecting revenues between $24 million and $26 million, primarily supported by expected revenues from government-related development services in the second half of 2026, demonstrating the company's confidence in future growth prospects.
See More
MediWound Advances ESCAREX Program Towards Commercialization
- New Contract Support: MediWound Ltd has signed a 10-year contract with BARDA valued at up to $197 million, aimed at supporting NexoBrid's strategic role in mass casualty burn response, thereby enhancing the company's position in the emergency medical market.
- Revenue Guidance Confirmation: The company reaffirmed its revenue guidance for 2026 at $24 million to $26 million, with expected support from government-related development services, demonstrating confidence in future revenue streams.
- Increased R&D Spending: R&D expenses rose from $2.9 million to $5.2 million in Q1 2026, reflecting ongoing investment in the ESCAREX study, although this resulted in an operating loss of $8 million, indicating short-term financial pressure.
- Market Potential Expansion: The market potential for Escorex is validated by an industry consensus document, with peak sales projections reaching $831 million from venous leg ulcers and diabetic foot ulcers, indicating a positive commercial outlook in the chronic wound care sector.
See More
Mediwound Shares Enter Oversold Territory
- Oversold Signal: Mediwound Ltd. (Ticker: MDWD) saw its RSI drop to 26.3 on Wednesday, indicating the stock has entered oversold territory, suggesting that the recent heavy selling pressure may be waning, thus providing potential buying opportunities for investors.
- Price Fluctuation: MDWD's stock price hit a low of $14.14 during trading, with the current trading price at $14.33, reflecting a 52-week low of $14.14 and a high of $22.505, indicating significant market volatility.
- Market Comparison: In contrast, the S&P 500 ETF (SPY) has an RSI of 74.2, highlighting MDWD's oversold condition, which may attract investors looking for low-entry opportunities in the market.
- Investor Sentiment: Despite the current low stock price, investors may view this as a favorable entry point, especially as the RSI indicates oversold conditions, potentially leading to increased buying activity.
See More
MediWound Q1 Earnings Beat Expectations Despite Revenue Decline
- Earnings Beat: MediWound reported a Q1 GAAP EPS of -$0.23, surpassing expectations by $0.42, indicating resilience in profitability despite overall revenue decline.
- Significant Revenue Drop: The company’s Q1 revenue of $1.48M fell 62.6% year-over-year and missed expectations, primarily due to the timing of BARDA-related revenues and delayed shipments from regional conflicts, highlighting external challenges impacting operations.
- Full-Year Guidance Reaffirmed: MediWound reaffirmed its 2026 revenue guidance of $24 million to $26 million, with anticipated revenue from government-related development services in the second half of 2026, reflecting confidence in future growth prospects.
- Clinical Program Expansion: The company showcased its expansion plans for the EscharEx clinical programs at the European Wound Management Association (EWMA) 2026, demonstrating ongoing investment and strategic positioning in innovative treatment solutions.
See More
MediWound to Announce Q1 Earnings on May 27
- Earnings Announcement: MediWound (MDWD) is set to release its Q1 2023 earnings on May 27 before market open, with a consensus EPS estimate of -$0.66, reflecting a staggering 842.9% year-over-year decline, indicating significant profitability challenges ahead.
- Revenue Expectations: The anticipated revenue for Q1 stands at $3.37 million, representing a 99.9% year-over-year drop, which highlights major hurdles in market competition and product sales, potentially undermining investor confidence.
- Historical Performance Review: Over the past two years, MediWound has only surpassed EPS estimates 38% of the time and revenue estimates 63% of the time, showcasing uncertainty in the company's earnings forecasts that could lead to stock price volatility.
- Estimate Revision Trends: In the last three months, EPS estimates have seen one upward revision and two downward adjustments, while revenue estimates experienced two upward and two downward revisions, indicating a divergence in analyst outlooks on the company's future performance that may impact investor decisions.
See More
U.S. Expert Consensus Supports MediWound's Chronic Wound Treatment Strategy
- Consensus Redefines Debridement: The U.S. multidisciplinary expert panel's consensus redefines debridement as a biologically active intervention that drives healing by reducing biofilm and bacterial burden, providing theoretical support for MediWound's EscharEx® and potentially enhancing its application in the chronic wound care market.
- Importance of Early Treatment: The consensus advocates for prioritizing effective, less invasive treatment methods when appropriate, which not only improves patient treatment experiences but may also reduce healthcare costs, thereby strengthening EscharEx®'s competitive position as a first-line debridement therapy.
- Clinical Research Support: EscharEx® has demonstrated good safety and efficacy in multiple Phase II clinical studies, enabling rapid removal of non-viable tissue and promoting granulation, laying the groundwork for its application in the upcoming Phase III VALUE trial targeting venous leg ulcers, indicating significant market potential.
- Global Market Opportunity: MediWound's innovative EscharEx® therapy for chronic wounds, which combines multiple therapeutic actions, is expected to meet the growing global demand for advanced debridement solutions, further solidifying the company's leadership position in the biotherapeutics field.
See More
