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  5. MAIA Biotechnology Launches New Lung Cancer Therapy with $34.1 Billion Market Potential

MAIA Biotechnology Launches New Lung Cancer Therapy with $34.1 Billion Market Potential

Written by Emily J. Thompson, Senior Investment Analyst
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MAIA.A+10.14%
Source: Globenewswire
Updated: 22 hour ago
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Source: Globenewswire
  • New Treatment Direction: MAIA Biotechnology's ateganosine is considered the first telomere-targeting drug for non-small cell lung cancer (NSCLC) patients, aiming to address the treatment gap for those without actionable mutations, which could significantly improve prognosis for this underserved population.
  • Market Size Growth: The global NSCLC market is estimated at $34.1 billion in 2024 and is projected to nearly double to $68.8 billion by 2033, highlighting the substantial commercial opportunity for this new therapy.
  • FDA Fast Track Designation: The drug has received Fast Track Designation from the U.S. FDA, indicating its potential importance in treating patients resistant to immunotherapy and chemotherapy, which could position it as a key option in future treatments.
  • Multiple Market Opportunities: Beyond lung cancer, ateganosine has also received Orphan Drug Designations for glioblastoma, hepatocellular carcinoma, and small cell lung cancer, further strengthening MAIA's market position and long-term growth potential in oncology.
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About MAIA
MAIA Biotechnology, Inc. is a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer. The Company's THIO (6-thio-dG, 6-thio-2'-deoxyguanosine), is a lead asset, is an investigational dual mechanism of action drug candidate incorporating telomere targeting and immunogenicity. The modified nucleotide 6-thio-2-deoxyguanosine (THIO) induces telomerase-dependent telomeric DNA modification, DNA damage responses, and selective cancer cell death. THIO-damaged telomeric fragments accumulate in cytosolic micronuclei and activates both innate (cGAS/STING) and adaptive (T-cell) immune responses. The sequential treatment with THIO followed by PD-(L)1 inhibitors resulted in tumor regression in advanced, in vivo cancer models by induction of cancer type-specific immune memory. THIO is being developed as a second or later line of treatment for NSCLC for patients that have progressed beyond the standard-of-care regimen of existing checkpoint inhibitors.

About the author

Emily J. Thompson
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Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.

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What is ateganosine's primary target in non-small cell lung cancer treatment?

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Why is ateganosine considered a breakthrough for NSCLC patients without actionable mutations?

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How might the NSCLC market value change by 2033 with ateganosine's success?

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What could be the financial impact of ateganosine's FDA Fast Track Designation?

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How does ateganosine address unmet needs in the NSCLC patient population?

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