LivaNova Presents Significant Seizure Reduction with VNS Therapy at AES Annual Meeting
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 03 2025
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Source: Newsfilter
- Clinical Research Findings: LivaNova will present eight posters at the American Epilepsy Society Annual Meeting, highlighting the CORE-VNS study's results, which demonstrate significant seizure frequency reduction and improved quality of life for patients with Drug-Resistant Epilepsy (DRE) through VNS Therapy.
- Data Support: The CORE-VNS study is the largest prospective multinational observational study to date, enrolling over 800 patients, providing robust data that aids clinicians in making evidence-based decisions regarding epilepsy treatment.
- Early Intervention Impact: The research indicates that patients who received VNS Therapy after 2-3 anti-seizure medications achieved a 94% median reduction in seizure frequency at 36 months, compared to a 57% reduction for those treated after more than 10 medications, underscoring the importance of early intervention.
- Healthcare Resource Utilization: The study also reveals high healthcare resource utilization among patients with DRE prior to VNS Therapy, indicating significant unmet needs in this area and further promoting the clinical application of VNS Therapy.
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Analyst Views on LIVN
Wall Street analysts forecast LIVN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for LIVN is 72.50 USD with a low forecast of 64.00 USD and a high forecast of 85.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
8 Analyst Rating
6 Buy
2 Hold
0 Sell
Strong Buy
Current: 63.910
Low
64.00
Averages
72.50
High
85.00
Current: 63.910
Low
64.00
Averages
72.50
High
85.00
About LIVN
LivaNova PLC is a medical technology company. The Company designs, develops, manufactures, markets and sells products and therapies. Its segments include Cardiopulmonary, and Neuromodulation. Its Cardiopulmonary segment is engaged in the design, development, manufacture, marketing, and sale of cardiopulmonary products, including heart-lung machines (HLM), oxygenators, autotransfusion systems, perfusion tubing systems, cannula, and other related accessories. Its Neuromodulation segment is engaged in the design, development, manufacture, marketing, and sale of devices that deliver neuromodulation therapy for treating drug-resistant epilepsy (DRE) and difficult-to-treat depression (DTD). Its principal Neuromodulation product, the VNS Therapy System, consists of an implantable pulse generator and connective lead that stimulates the vagus nerve, surgical equipment to assist with the implant procedure, and equipment and instruction manuals.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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