Ionis Pharmaceuticals Adjusts Webcast Time for Q4 2025 Results
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1 day ago
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Should l Buy IONS?
Source: Newsfilter
- Webcast Time Change: Ionis Pharmaceuticals has announced a change in the start time for its Q4 and full year 2025 financial results webcast from the previously scheduled 11:30 a.m. Eastern Time to 8:30 a.m. Eastern Time, while the date remains unchanged, which may affect investor participation and information access.
- Webcast Access Information: Investors can access the live webcast at https://ir.ionis.com/events-and-presentations/upcoming-events, with a replay available for a limited time at the same address, ensuring that those unable to attend live can still obtain critical information.
- Company Background: For three decades, Ionis has focused on inventing medicines for serious diseases, boasting marketed products and a leading pipeline in neurology and cardiometabolic diseases, highlighting its deep expertise and innovative capabilities in the biopharmaceutical sector.
- Technological Innovation and Market Positioning: As a pioneer in RNA-targeted medicines, Ionis continues to drive innovation in RNA therapies while exploring new approaches in gene editing, demonstrating its leadership in the biotechnology industry and commitment to improving patient quality of life.
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Analyst Views on IONS
Wall Street analysts forecast IONS stock price to rise
14 Analyst Rating
13 Buy
1 Hold
0 Sell
Strong Buy
Current: 81.360
Low
65.00
Averages
92.67
High
110.00
Current: 81.360
Low
65.00
Averages
92.67
High
110.00
About IONS
Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Ionis Pharmaceuticals Adjusts Webcast Time for Q4 2025 Results
- Webcast Time Change: Ionis Pharmaceuticals has announced a change in the start time for its Q4 and full year 2025 financial results webcast from the previously scheduled 11:30 a.m. Eastern Time to 8:30 a.m. Eastern Time, while the date remains unchanged, which may affect investor participation and information access.
- Webcast Access Information: Investors can access the live webcast at https://ir.ionis.com/events-and-presentations/upcoming-events, with a replay available for a limited time at the same address, ensuring that those unable to attend live can still obtain critical information.
- Company Background: For three decades, Ionis has focused on inventing medicines for serious diseases, boasting marketed products and a leading pipeline in neurology and cardiometabolic diseases, highlighting its deep expertise and innovative capabilities in the biopharmaceutical sector.
- Technological Innovation and Market Positioning: As a pioneer in RNA-targeted medicines, Ionis continues to drive innovation in RNA therapies while exploring new approaches in gene editing, demonstrating its leadership in the biotechnology industry and commitment to improving patient quality of life.
See More
Ionis Pharmaceuticals to Host Webcast on February 25 for Q4 and Full Year 2025 Results
- Webcast Announcement: Ionis Pharmaceuticals has announced a live webcast scheduled for February 25, 2025, at 11:30 a.m. Eastern Time to discuss its fourth quarter and full year financial results, aiming to provide investors and stakeholders with the latest company updates.
- Financial Highlights: The webcast will highlight Ionis's progress on key programs in neurology, cardiometabolic diseases, and other areas of high patient need, showcasing the company's innovative capabilities and market potential in RNA-targeted medicines.
- Replay Availability: Attendees can access the webcast through a designated link, with a limited-time replay available afterward, ensuring that investors who cannot participate live can still obtain relevant information.
- Company Background: For three decades, Ionis Pharmaceuticals has focused on inventing medicines that improve the futures of patients with serious diseases, leveraging a deep understanding of disease biology and industry-leading technology to drive innovation in RNA therapies and new gene editing approaches.
See More
Clinical Benefits of High-Dose Nusinersen Confirmed in DEVOTE Study
- Significant Clinical Outcomes: The DEVOTE study demonstrated that the high-dose nusinersen regimen of 50 mg and 28 mg significantly improved motor function in treatment-naïve and previously treated patients, with a mean difference of 26.19 points in CHOP-INTEND scores compared to the matched sham group, indicating its potential in clinical applications.
- Neurodegeneration Slowed: The high-dose regimen showed a more rapid reduction in neurofilament levels compared to the 12 mg regimen, highlighting its advantages in slowing the progression of spinal muscular atrophy (SMA) and potentially improving patients' quality of life.
- Good Safety and Tolerability: The safety profile of the high-dose regimen was broadly consistent with the 12 mg regimen, with common adverse events such as pneumonia and respiratory failure observed, yet the overall incidence of adverse events remained within acceptable limits, supporting its clinical feasibility.
- FDA Review Progress: The high-dose nusinersen is currently under review by the U.S. FDA, with a decision expected by April 3, 2026, which will provide SMA patients with a more effective treatment option and further solidify Biogen's leadership position in the biopharmaceutical sector.
See More
Clinical Findings on High-Dose Nusinersen Published
- Clinical Study Results: Biogen's DEVOTE study results indicate that the high-dose nusinersen (50 mg and 28 mg) demonstrates significant safety and efficacy in spinal muscular atrophy (SMA) patients, particularly in treatment-naïve infants, with a mean difference of 26.19 points in motor function improvement, p<0.0001, highlighting its clinical potential.
- Neurodegeneration Biomarker Improvement: The high-dose regimen significantly accelerated the reduction of neurofilament, a marker of neurodegeneration, suggesting its advantage in slowing disease progression, which could reshape treatment strategies for SMA and enhance patient quality of life.
- FDA Review Progress: The high-dose nusinersen is currently under review by the U.S. FDA, with a decision expected by April 3, 2026, potentially providing patients with a more effective treatment option and further solidifying Biogen's leadership in the SMA treatment landscape.
- Positive Feedback from Diverse Patient Groups: In the open-label part of the DEVOTE study, 40 participants showed mean increases of 1.8 points on the Hammersmith Functional Motor Scale and 1.2 points on the Revised Upper Limb Module after transitioning to the high-dose regimen, demonstrating broad applicability across different ages and disease stages, boosting Biogen's confidence in future market opportunities.
See More
Ionis Pharmaceuticals Insider Sold Shares Worth $323,490, According to a Recent SEC Filing
See More
Ark Invest Unveils 2026 Big Ideas, Forecasts 1.9% GDP Growth Boost
- Technological Acceleration: Ark Invest's report highlights that capital investment in disruptive innovation platforms could contribute 1.9 percentage points to annualized real GDP growth during this decade, emphasizing the potential of technologies like robotaxis and next-gen data centers.
- Strong ETF Performance: In 2025, Ark's Autonomous Technology & Robotics ETF and Space & Defense Innovation ETF achieved returns of 49.8% and 49.2%, respectively, showcasing the firm's ability to generate returns in emerging technology sectors.
- Bitcoin Holdings Surge: The report indicates that U.S. ETFs and public companies now hold 12% of total Bitcoin supply, with Bitcoin ETF balances up 19.7% and public company Bitcoin holdings up 73% in 2025, reflecting strong market demand for digital assets.
- Diverse Investment Opportunities: Ark Invest identifies several publicly traded companies, including Coinbase, Illumina, and Waymo, as key investment opportunities for the 2026 themes, indicating the firm's forward-looking approach to diversified investment strategies.
See More
Ionis Pharmaceuticals Adjusts Webcast Time for Q4 2025 Results
- Webcast Time Change: Ionis Pharmaceuticals has announced a change in the start time for its Q4 and full year 2025 financial results webcast from the previously scheduled 11:30 a.m. Eastern Time to 8:30 a.m. Eastern Time, while the date remains unchanged, which may affect investor participation and information access.
- Webcast Access Information: Investors can access the live webcast at https://ir.ionis.com/events-and-presentations/upcoming-events, with a replay available for a limited time at the same address, ensuring that those unable to attend live can still obtain critical information.
- Company Background: For three decades, Ionis has focused on inventing medicines for serious diseases, boasting marketed products and a leading pipeline in neurology and cardiometabolic diseases, highlighting its deep expertise and innovative capabilities in the biopharmaceutical sector.
- Technological Innovation and Market Positioning: As a pioneer in RNA-targeted medicines, Ionis continues to drive innovation in RNA therapies while exploring new approaches in gene editing, demonstrating its leadership in the biotechnology industry and commitment to improving patient quality of life.
See More
Ionis Pharmaceuticals to Host Webcast on February 25 for Q4 and Full Year 2025 Results
- Webcast Announcement: Ionis Pharmaceuticals has announced a live webcast scheduled for February 25, 2025, at 11:30 a.m. Eastern Time to discuss its fourth quarter and full year financial results, aiming to provide investors and stakeholders with the latest company updates.
- Financial Highlights: The webcast will highlight Ionis's progress on key programs in neurology, cardiometabolic diseases, and other areas of high patient need, showcasing the company's innovative capabilities and market potential in RNA-targeted medicines.
- Replay Availability: Attendees can access the webcast through a designated link, with a limited-time replay available afterward, ensuring that investors who cannot participate live can still obtain relevant information.
- Company Background: For three decades, Ionis Pharmaceuticals has focused on inventing medicines that improve the futures of patients with serious diseases, leveraging a deep understanding of disease biology and industry-leading technology to drive innovation in RNA therapies and new gene editing approaches.
See More
Clinical Benefits of High-Dose Nusinersen Confirmed in DEVOTE Study
- Significant Clinical Outcomes: The DEVOTE study demonstrated that the high-dose nusinersen regimen of 50 mg and 28 mg significantly improved motor function in treatment-naïve and previously treated patients, with a mean difference of 26.19 points in CHOP-INTEND scores compared to the matched sham group, indicating its potential in clinical applications.
- Neurodegeneration Slowed: The high-dose regimen showed a more rapid reduction in neurofilament levels compared to the 12 mg regimen, highlighting its advantages in slowing the progression of spinal muscular atrophy (SMA) and potentially improving patients' quality of life.
- Good Safety and Tolerability: The safety profile of the high-dose regimen was broadly consistent with the 12 mg regimen, with common adverse events such as pneumonia and respiratory failure observed, yet the overall incidence of adverse events remained within acceptable limits, supporting its clinical feasibility.
- FDA Review Progress: The high-dose nusinersen is currently under review by the U.S. FDA, with a decision expected by April 3, 2026, which will provide SMA patients with a more effective treatment option and further solidify Biogen's leadership position in the biopharmaceutical sector.
See More
Clinical Findings on High-Dose Nusinersen Published
- Clinical Study Results: Biogen's DEVOTE study results indicate that the high-dose nusinersen (50 mg and 28 mg) demonstrates significant safety and efficacy in spinal muscular atrophy (SMA) patients, particularly in treatment-naïve infants, with a mean difference of 26.19 points in motor function improvement, p<0.0001, highlighting its clinical potential.
- Neurodegeneration Biomarker Improvement: The high-dose regimen significantly accelerated the reduction of neurofilament, a marker of neurodegeneration, suggesting its advantage in slowing disease progression, which could reshape treatment strategies for SMA and enhance patient quality of life.
- FDA Review Progress: The high-dose nusinersen is currently under review by the U.S. FDA, with a decision expected by April 3, 2026, potentially providing patients with a more effective treatment option and further solidifying Biogen's leadership in the SMA treatment landscape.
- Positive Feedback from Diverse Patient Groups: In the open-label part of the DEVOTE study, 40 participants showed mean increases of 1.8 points on the Hammersmith Functional Motor Scale and 1.2 points on the Revised Upper Limb Module after transitioning to the high-dose regimen, demonstrating broad applicability across different ages and disease stages, boosting Biogen's confidence in future market opportunities.
See More
Ionis Pharmaceuticals Insider Sold Shares Worth $323,490, According to a Recent SEC Filing
See More
Ark Invest Unveils 2026 Big Ideas, Forecasts 1.9% GDP Growth Boost
- Technological Acceleration: Ark Invest's report highlights that capital investment in disruptive innovation platforms could contribute 1.9 percentage points to annualized real GDP growth during this decade, emphasizing the potential of technologies like robotaxis and next-gen data centers.
- Strong ETF Performance: In 2025, Ark's Autonomous Technology & Robotics ETF and Space & Defense Innovation ETF achieved returns of 49.8% and 49.2%, respectively, showcasing the firm's ability to generate returns in emerging technology sectors.
- Bitcoin Holdings Surge: The report indicates that U.S. ETFs and public companies now hold 12% of total Bitcoin supply, with Bitcoin ETF balances up 19.7% and public company Bitcoin holdings up 73% in 2025, reflecting strong market demand for digital assets.
- Diverse Investment Opportunities: Ark Invest identifies several publicly traded companies, including Coinbase, Illumina, and Waymo, as key investment opportunities for the 2026 themes, indicating the firm's forward-looking approach to diversified investment strategies.
See More
