Indivior Reports SUBLOCADE Trial Results, 300mg Dose Significantly Increases Abstinence Rates
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 17 2025
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Source: Newsfilter
- Clinical Trial Success: Indivior PLC's randomized double-blind trial results indicate that the 300mg monthly maintenance dose of SUBLOCADE significantly improves abstinence rates among high-frequency fentanyl users, suggesting its effectiveness for specific patient populations.
- Rapid Reduction in Use: Participants experienced a dramatic decrease in opioid use frequency from over 43 instances per week to fewer than three by week three, demonstrating SUBLOCADE's rapid efficacy in treating moderate to severe opioid use disorder (OUD), thereby enhancing its market competitiveness.
- Good Safety Profile: Although injection site reactions were more common in the 300mg group, they were mild to moderate and did not lead to discontinuation, indicating the drug's acceptable safety profile, which can enhance patient adherence.
- Treatment Strategy Adaptation: The findings underscore the need for clinicians to consider varying dosage regimens in the context of the fentanyl crisis to better meet patient needs, thereby increasing the likelihood of successful treatment outcomes.
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Analyst Views on INDV
Wall Street analysts forecast INDV stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for INDV is 38.00 USD with a low forecast of 35.00 USD and a high forecast of 41.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
5 Analyst Rating
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 35.380
Low
35.00
Averages
38.00
High
41.00
Current: 35.380
Low
35.00
Averages
38.00
High
41.00
About INDV
Indivior PLC is a global pharmaceutical company engaged in developing medicines to treat substance-use disorders (SUD). The Company provides treatment for addiction, including SUBLOCADE (buprenorphine extended-release) injection for subcutaneous use, a long-acting injectable (LAI) for opioid use disorder and OPVEE (Nalmefene) nasal spray for opioid overdose recovery. Its core products include SUBOXONE Film, SUBOXONE Tablet, SUBUTEX Tablet, OPVEE (nalmefene), and SUBLOCADE. SUBOXONE Film is a buprenorphine and naloxone sublingual film. SUBOXONE Tablet is a buprenorphine and naloxone sublingual tablet. SUBUTEX Tablet is a buprenorphine sublingual tablet. SUBOXONE Film, SUBOXONE Tablet, SUBUTEX Tablet, and SUBLOCADE are treatments for opioid use disorder (OUD). In addition to its commercially available products, its product pipeline includes two drug candidates for the treatment of OUD. The Company sells its products in the United States and in other selected areas of the world.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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