Geron Expects FY26 Total Operating Expenses Between $230 Million and $240 Million
Sees FY26 total operating expenses expected in the range of $230 million to $240 million. "Our priorities for 2026 are clear - driving RYTELO commercial growth in the U.S., pursuing paths to bring RYTELO to LR-MDS markets outside the U.S., and advancing our Phase 3 IMpactMF trial," said Harout Semerjian, President and Chief Executive Officer of Geron. "These priorities are supported by a focused commercial strategy, an expanding body of RYTELO scientific evidence and real-world experience, and a streamlined and energized Geron team. Together, these strengths are designed to drive deeper engagement across the hematology community and reinforce our conviction that we can deliver for eligible LR-MDS patients and build Geron into a leading, sustainable hematology company."
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Geron Corporation (GERN) Projects $220M-$240M Net Revenue for Rytelo in 2026
- Financial Guidance: Geron Corporation anticipates net product revenue for Rytelo to range between $220 million and $240 million in 2026, reflecting the company's confidence in future revenue growth while also indicating efforts to reduce operating expenses.
- Operating Expense Control: Total operating expenses are expected to be between $230 million and $240 million in 2026, demonstrating progress in optimizing cost structures, thereby laying the groundwork for future profitability.
- Product Approval Status: Rytelo has been approved in the U.S. for treating lower-risk myelodysplastic syndrome (LR-MDS) with transfusion-dependent anemia and in the EU as a monotherapy for adult patients, showcasing its market potential.
- Market Outlook: With Rytelo's approvals across multiple regions, Geron Corporation is poised to seize market opportunities for treating low-risk MDS patients in the coming years, further driving overall company growth.

Geron (GERN) Projects $220M-$240M Net Revenue from RYTELO by 2026
- Revenue Projection: Geron anticipates net product revenue from RYTELO (imetelstat) to range between $220 million and $240 million in 2026, reflecting confidence in market demand and future growth potential.
- Cost Management: Total operating expenses are expected to be between $230 million and $240 million in 2026, demonstrating cost optimization achieved through strategic restructuring aimed at enhancing financial stability.
- Market Strategy: CFO Michelle Robertson indicated that revenue growth for RYTELO will be driven by more focused targeting of healthcare providers and patients, with stronger performance expected in the second half of the year, highlighting the company's proactive market positioning.
- Restructuring Plan: Geron is implementing a strategic restructuring plan that includes laying off a third of its workforce to support RYTELO's commercial strategy and clinical development priorities, aiming to improve overall operational efficiency.






