Galapagos Achieves Key Objective in Phase 3 Study for Rare Autoimmune Disease Treatment
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 18 2025
0mins
Source: SeekingAlpha
Phase 3 Study Results: Galapagos NV's selective TYK2 inhibitor, GLPG3667, successfully met its primary endpoint in a phase 3-enabling study for dermatomyositis, showing significant clinical benefits compared to placebo.
Lupus Study Outcome: A second phase 3-enabling study of GLPG3667 for lupus did not meet its primary endpoint, prompting the company to explore strategic options for further development.
Future Plans: The company plans to resume partnering discussions to accelerate the development of GLPG3667 for dermatomyositis following the positive results from the GALARISSO study.
Market Reaction: Following the announcement, Galapagos shares experienced a decline of approximately 3.6% in after-hours trading.
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Analyst Views on GLPG
Wall Street analysts forecast GLPG stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for GLPG is 30.50 USD with a low forecast of 22.00 USD and a high forecast of 40.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
4 Analyst Rating
1 Buy
1 Hold
2 Sell
Hold
Current: 34.100
Low
22.00
Averages
30.50
High
40.00
Current: 34.100
Low
22.00
Averages
30.50
High
40.00
About GLPG
Galapagos NV is a Belgium-based clinical-stage biotechnology company. The Company is engaged in the discovery and development of small molecule medicines with modes of action. Its pipeline comprises Phase 3, 2, 1, pre-clinical studies and discovery small-molecule and antibody programs in cystic fibrosis, inflammation, and other indications. The Company focuses on developing a portfolio of clinical-stage therapies for the enhancement of existing treatment paradigms. It develops transformational medicines in areas of high unmet need by combining internal with external science with the goal to add years of life and improve of life of patients across the globe. It discovers which proteins that are involved in causing diseases such as, rheumatoid, arthritis, inflammatory bowel disease and fibrosis. The Company acquired CellPoint and AboundBio in order to develop a cell therapy, which is a potential transformative treatment of different types of cancer.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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