Evaxion Releases New Data Demonstrating Vaccine Development Potential
Evaxion A/S announces new data demonstrating the platform's ability to also potentially develop vaccines for glioblastoma. The data, which will be presented at the AACR Annual Meeting in San Diego, California, on April 22, is "another confirmation of how AI-Immunology can be applied across a range of different cancers as well as other diseases," the company stated. "We are excited by these new findings confirming that AI-Immunology is a unique platform for designing vaccines for many different cancer types, combining neoantigens with other types of antigens. This holds great potential for improving vaccine efficacy, and we are looking forward to discussing the data with both scientific stakeholders and potential business partners at the AACR Annual Meeting," says Birgitte Rono, CSO of Evaxion.
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- Award Recognition: Evaxion A/S has been awarded the 2026 Prix Galien UK Award for Best Digital Health Solution for its AI-Immunology™ platform, highlighting its innovative capabilities and industry impact in vaccine development.
- Leadership Presentation: CEO Helen Tayton-Martin received the award at the ceremony held at the Natural History Museum in London, indicating the company's growing recognition within the scientific community and enhancing its market competitiveness.
- Continuous Innovation: The AI-Immunology™ platform utilizes artificial intelligence to decode the human immune system, driving the development of vaccines for cancer and infectious diseases, reflecting Evaxion's commitment to addressing unmet medical needs.
- Historical Achievements: This marks Evaxion's second Prix Galien award in less than a year, underscoring its significant contributions to biomedical science and human health, further solidifying its leadership position in the industry.
- Immune Response Activation: Evaxion's EVX-04 vaccine successfully triggers specific immune responses against acute myeloid leukemia (AML) in both mouse and human immune cell assays, demonstrating its potential as a new treatment approach for a cancer with poor long-term outcomes.
- Consistent Antigen Expression: The study shows that EVX-04 is correctly transcribed, translated, and secreted in human cells, ensuring that the immune system can recognize the vaccine antigens, thereby enhancing immune responses against AML and addressing the urgent need for new therapies.
- AI-Driven Antigen Selection: EVX-04 utilizes Evaxion's AI-Immunology platform to identify 16 tumor-specific antigens from the

- Successful Vaccine Expression: Evaxion's EVX-04 vaccine has been successfully expressed and secreted in human cells, enabling immune recognition and activation, showcasing its potential as a novel treatment for acute myeloid leukemia (AML).
- Immune Response Induction: New data indicates that all endogenous retrovirus (ERV) antigens in EVX-04 drive specific immune responses in both mice and human cells, suggesting promising applications in cancer immunotherapy.
- Clinical Preparation Progress: Evaxion is actively executing preclinical activities while preparing regulatory filings for clinical testing, with data set to be presented at the European Hematology Association Congress on June 13, 2026, potentially enhancing treatment options for AML patients.
- Platform Advantage: The development of EVX-04 leverages the AI-Immunology™ platform, which utilizes artificial intelligence to identify and select antigen fragments with the highest potential for immune recognition, ensuring broad tumor coverage across different patients, highlighting its strategic significance.
- Financial Performance: Evaxion Biotech reported a Q1 2026 GAAP EPS of -$0.01, indicating challenges in profitability, particularly with a significant drop in financial income compared to the same period last year.
- Decline in Financial Income: The financial income for Q1 2026 was $0.3 million, a stark decrease from $2.4 million in the prior year, primarily due to the remeasurement of derivative liabilities from the January 2025 public offering, reflecting the impact of market volatility on the company.
- Cash Flow Status: As of March 31, 2026, the company's cash and cash equivalents stood at $18.4 million, down from $23.2 million as of December 31, 2025, confirming the company's liquidity runway until the second half of 2027.
- Equity Changes: Total equity amounted to $13.2 million as of March 31, 2026, a decrease from $17.0 million as of December 31, 2025, indicating the impact of the net results from the first quarter on the company's financial health.

- Clinical Trial Success Rate: Evaxion A/S's personalized cancer vaccine EVX-01 achieved an impressive 86% success rate in triggering tumor-specific immune responses during its Phase 2 trial for advanced melanoma, indicating the therapy's efficacy and potential.
- Durable Immune Responses: The two-year analysis confirmed that EVX-01 generated durable immune responses, including robust de novo T-cell activity, which may enhance tumor-killing potential, thereby providing better treatment options for patients.
- AI Platform Application: Evaxion's proprietary AI-Immunology platform played a crucial role in the precise selection of vaccine targets with unprecedented accuracy, with Chief Scientific Officer Bigitte Rønø emphasizing that these findings validate the platform's powerful potential in developing transformational cancer treatments.
- Technology Scalability: Evaxion reported progress in applying its AI-Immunology platform to glioblastoma, with preclinical findings demonstrating the successful design of personalized vaccines targeting glioblastoma, highlighting the technology's scalability beyond melanoma and its significant clinical implications.








