CytoMed Partners with UMMC for First-in-Human Cancer Immunotherapy Trial
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 08 2025
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Source: Newsfilter
- Clinical Trial Launch: CytoMed has signed a Memorandum of Understanding with Universiti Malaya Medical Centre to initiate a first-in-human Phase I clinical trial aimed at assessing the safety and efficacy of its patented γδ T cell therapy for no-option cancer patients, which is expected to provide new treatment options for Malaysian patients.
- Technological Advantage: CytoMed's γδ T cell therapy utilizes cells derived from healthy donors, avoiding the high costs and complexities associated with autologous therapies, thereby enhancing accessibility for patients, including those from overseas, which presents significant market potential.
- Research Collaboration: CytoMed's partnership with MD Anderson Cancer Center has shown promising results for γδ T cells in treating acute myeloid leukemia, further supporting the application potential of its therapies in cancer treatment and advancing clinical research efforts.
- Strategic Goals: This collaboration with UMMC not only reflects CytoMed's commitment to the Southeast Asian market but also aims to provide more viable treatment options for cancer patients through innovative immunotherapy, aligning with the company's long-term growth strategy.
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About GDTC
CytoMed Therapeutics Limited is a biopharmaceutical company. It is focused on harnessing its licensed proprietary technologies, namely gamma delta T cell and gamma delta Natural Killer T cel to create cell-based immunotherapies for the treatment of human cancers. The development of its technologies has been inspired by the clinical success of existing CAR-T in treating hematological malignancies as well as the clinical limitations and commercial challenges in extrapolating the CAR-T principle into treatment of solid tumors. Its product candidates include CTM-N2D, iPSC-gdNKT, and CTM-GDT. CTM-N2D is a lead product candidate that consists of expanded gamma delta T cells grafted with NKG2DL-targeting CAR to enhance anti-cancer cytotoxicity. The iPSC-gdNKT product candidate utilizes iPSC as a starting material to generate gdNKT, which is a synthetic hybrid of a gamma delta T cell and a NK cell. The Company also has the allogeneic gamma delta T cell technology, namely TCB-002.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
CytoMed Addresses False Claims, Reaffirms Research Progress
- Research Progress Statement: CytoMed is conducting its first CAR γδ T cell clinical trial at National University Hospital in Singapore, having received regulatory approval, marking a significant advancement in the company's cancer immunotherapy efforts, which is expected to drive further development of its product pipeline.
- Technological Focus: The company is focused on developing CAR γδ T cell and iPSC-derived γδ NKT cell therapies to address treatment needs for both blood and solid tumors, showcasing its innovative potential in the biopharmaceutical sector.
- Rebuttal of False Claims: CytoMed strongly rejects inaccurate statements regarding its research status and regulatory standing, emphasizing its commitment to compliance and transparency to protect shareholder interests and the company's reputation.
- Future Outlook: Despite external challenges, CytoMed remains dedicated to advancing its research pipeline and communicating accurate information through official channels, ensuring investor confidence in the company's future development.
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CytoMed Enters MOU with UMMC for First-in-Human Cancer Trial
- Trial Collaboration Initiated: CytoMed has signed a Memorandum of Understanding with Universiti Malaya Medical Centre to conduct a multi-site first-in-human Phase I clinical trial, aimed at evaluating the safety and efficacy of its patented γδ T cell therapy for no-option cancer patients, marking a strategic expansion into the Southeast Asian market.
- Technological Advantage: By utilizing donor-derived γδ T cells, CytoMed's therapy circumvents the high costs and logistical complexities associated with autologous treatments, making cancer immunotherapy more accessible and potentially providing a cost-effective option for Malaysian patients.
- Clinical Research Backing: Collaborative research with MD Anderson Cancer Center has demonstrated the potential of γδ T cells in treating acute myeloid leukemia, further solidifying the scientific foundation for CytoMed's clinical trials and driving innovation in cancer treatment.
- Broad Market Potential: This partnership with UMMC not only underscores CytoMed's commitment to emerging markets but also facilitates business growth in Southeast Asia, addressing the increasing demand for cancer therapies and enhancing the company's competitiveness in the global biopharmaceutical industry.
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