Cue Biopharma Appoints Shao-Lee Lin as CEO
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Apr 30 2026
0mins
Should l Buy CUE?
Cue Biopharma announced the appointment of Shao-Lee Lin as CEO president and director. Lin will succeed Lucinda Warren, interim president and CEO. Prior to joining Cue, Lin was founder and CEO of Acelyrin.
Trade with 70% Backtested Accuracy
Stop guessing "Should I Buy CUE?" and start using high-conviction signals backed by rigorous historical data.
Sign up today to access powerful investing tools and make smarter, data-driven decisions.
Analyst Views on CUE
About CUE
Cue Biopharma, Inc. is a clinical-stage biopharmaceutical company, developing a novel class of injectable biologics to selectively engage and modulate disease-specific T cells directly within the patient’s body. Its proprietary platform, Immuno-STAT (Selective Targeting and Alteration of T cells) and biologics are designed to harness the curative potential of the body’s intrinsic immune system through the selective modulation of disease-specific T cells without the adverse effects of broad systemic immune modulation. Its lead programs include drug product candidates designed to: CUE-400 series (Autoimmune Diseases) enhance regulatory T cells (Tregs) with a novel mechanism to proliferate, generate Tregs, and restore immune balance (CUE-401 for autoimmune conditions);CUE-500 series (Targeted Cell Depletion) redirect antiviral T cells to target eliminate pathogenic cells (CUE-501 for autoimmune B cell depletion); and CUE-100 series (Oncology) selectively activate tumor-specific T cells.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Cue Biopharma Grants Equity Awards to New Employees
- Executive Appointment and Equity Incentives: On May 3, 2026, Cue Biopharma granted equity awards to seven new employees, including newly appointed President and CEO Dr. Shao-Lee Lin, aimed at attracting and retaining talent in compliance with Nasdaq Listing Rule.
- Equity Award Details: Dr. Lin received a non-statutory stock option for 655,074 shares at an exercise price of $30.42 per share, along with 327,537 restricted stock units, which will enhance management stability and align interests with shareholders.
- Incentives for Other Employees: The other six new employees collectively received non-statutory stock options for 518,599 shares at the same exercise price of $30.42, along with 327,534 restricted stock units, with vesting scheduled over four years to strengthen team cohesion and retention.
- Strategic Company Context: Cue Biopharma focuses on developing transformative therapies for immunological disorders, currently advancing its lead asset in clinical trials, and the implementation of these equity incentives is expected to attract top industry talent, driving growth in the competitive biopharmaceutical market.
See More
Market Pauses After AI and Mega-Cap Tech Rally
- Market Pullback: Following the best April since 2020, U.S. stock futures were flat early Friday, with Dow, S&P 500, and Nasdaq futures showing no movement, while Russell 2000 futures dipped 0.1%, indicating a cautious sentiment among investors.
- Retail Sentiment Shift: Retail sentiment towards the SPDR S&P 500 ETF (SPY) has shifted from 'bullish' to 'extremely bullish', while the Invesco QQQ Trust (QQQ) remains in 'bullish' territory, reflecting a positive outlook among investors despite the market's pause.
- Stock Movements: Apple (AAPL) shares rose 3% in early trading after beating Q2 estimates, while Rivian Automotive (RIVN) fell 4% due to a lack of new model details, highlighting varied investor reactions across different stocks.
- Economic Data Watch: Traders are set to monitor the upcoming April manufacturing data release, alongside quarterly earnings reports from major companies like Exxon Mobil (XOM) and Chevron (CVX) before the market opens, which could significantly influence market direction.
See More
CUE Biopharma Stock Soars 56.2% in Premarket Trading Following New CEO Announcement, Licensing Deal, and $30 Million Private Placement
Stock Performance: Cue Biopharma shares surged by 56.2% in pre-market trading.
Leadership Change: The increase follows the announcement of a new CEO for the company.
Licensing Agreement: Cue Biopharma has entered into a new license agreement, which is expected to impact its operations positively.
Funding Announcement: The company also revealed a $30 million private placement to support its initiatives.
See More
Cue Biopharma Secures $30 Million Financing and Appoints New CEO
- Financing Agreement: Cue Biopharma has entered into a securities purchase agreement with accredited investors, aiming to raise approximately $30 million through a private placement, which will be utilized to advance the company's clinical pipeline and other general corporate purposes, demonstrating strong financing capabilities in the biopharmaceutical sector.
- New CEO Appointment: The company has appointed Shao-Lee Lin as the new Chief Executive Officer, President, and Director, bringing over 25 years of leadership experience in the biopharmaceutical industry, having held executive roles in several prominent companies, which is expected to drive strategic development and innovation within the firm.
- Exclusive License Agreement: Cue Biopharma has signed an exclusive license agreement with Ascendant Health Sciences, granting global rights to develop and commercialize Ascendant-221, potentially yielding up to $676.5 million in milestone payments, thereby enhancing its market position in the treatment of allergic diseases.
- Clinical Trial Plans: Cue Biopharma plans to initiate a global Phase 2b trial for food allergies in the second half of 2026, based on expected results from the Ascendant Health-led Phase 2 study in chronic spontaneous urticaria, which will further propel the product development process.
See More
Cue Biopharma Secures $30 Million Financing and New CEO
- Financing Boosts Cash Flow: Cue Biopharma entered into a securities purchase agreement with accredited investors to raise approximately $30 million in net proceeds through a private placement, significantly enhancing the company's financial position to support its clinical pipeline and general corporate purposes.
- Exclusive License Expands Pipeline: The company announced it has obtained an exclusive license for Ascendant-221 from Ascendant Health Sciences, an experimental drug aimed at treating specific allergic diseases, with mid-stage clinical data expected in the second half of 2026, thereby enriching the company's product pipeline.
- New CEO Appointment: Shao-Lee Lin has been appointed as the new President and CEO, previously raising over $1 billion and taking ACELYRIN public, indicating her leadership could drive Cue Biopharma's strategic growth.
- Positive Market Reaction: Following the financing and leadership changes, Cue Biopharma's shares surged nearly 100% in after-hours trading, reflecting strong investor confidence in the company's future, despite a 35% decline in stock price over the past year.
See More
Cue Biopharma Announces 1-for-30 Reverse Stock Split
- Reverse Stock Split Announcement: Cue Biopharma has announced a 1-for-30 reverse stock split effective April 23, 2026, aimed at boosting its stock price to comply with Nasdaq Capital Market listing rules, thereby enhancing the company's compliance and attractiveness in the capital market.
- Significant Share Reduction: Post-split, the total shares will decrease sharply from approximately 97.7 million to about 3.3 million, maintaining overall company value despite the drastic reduction in share count, which may impact investor ownership structure and market liquidity.
- Trading Adjustments: Starting April 24, 2026, CUE stock will trade on a split-adjusted basis, with all stock options, warrants, and equity plans adjusted accordingly to ensure investor rights are protected under the new structure.
- Negative Market Reaction: Following the reverse split announcement, CUE's stock price plummeted by about 25% to approximately $0.51, indicating market concerns regarding the decision, which could affect the company's future financing capabilities and investor confidence.
See More
Cue Biopharma Grants Equity Awards to New Employees
- Executive Appointment and Equity Incentives: On May 3, 2026, Cue Biopharma granted equity awards to seven new employees, including newly appointed President and CEO Dr. Shao-Lee Lin, aimed at attracting and retaining talent in compliance with Nasdaq Listing Rule.
- Equity Award Details: Dr. Lin received a non-statutory stock option for 655,074 shares at an exercise price of $30.42 per share, along with 327,537 restricted stock units, which will enhance management stability and align interests with shareholders.
- Incentives for Other Employees: The other six new employees collectively received non-statutory stock options for 518,599 shares at the same exercise price of $30.42, along with 327,534 restricted stock units, with vesting scheduled over four years to strengthen team cohesion and retention.
- Strategic Company Context: Cue Biopharma focuses on developing transformative therapies for immunological disorders, currently advancing its lead asset in clinical trials, and the implementation of these equity incentives is expected to attract top industry talent, driving growth in the competitive biopharmaceutical market.
See More
Market Pauses After AI and Mega-Cap Tech Rally
- Market Pullback: Following the best April since 2020, U.S. stock futures were flat early Friday, with Dow, S&P 500, and Nasdaq futures showing no movement, while Russell 2000 futures dipped 0.1%, indicating a cautious sentiment among investors.
- Retail Sentiment Shift: Retail sentiment towards the SPDR S&P 500 ETF (SPY) has shifted from 'bullish' to 'extremely bullish', while the Invesco QQQ Trust (QQQ) remains in 'bullish' territory, reflecting a positive outlook among investors despite the market's pause.
- Stock Movements: Apple (AAPL) shares rose 3% in early trading after beating Q2 estimates, while Rivian Automotive (RIVN) fell 4% due to a lack of new model details, highlighting varied investor reactions across different stocks.
- Economic Data Watch: Traders are set to monitor the upcoming April manufacturing data release, alongside quarterly earnings reports from major companies like Exxon Mobil (XOM) and Chevron (CVX) before the market opens, which could significantly influence market direction.
See More
CUE Biopharma Stock Soars 56.2% in Premarket Trading Following New CEO Announcement, Licensing Deal, and $30 Million Private Placement
Stock Performance: Cue Biopharma shares surged by 56.2% in pre-market trading.
Leadership Change: The increase follows the announcement of a new CEO for the company.
Licensing Agreement: Cue Biopharma has entered into a new license agreement, which is expected to impact its operations positively.
Funding Announcement: The company also revealed a $30 million private placement to support its initiatives.
See More
Cue Biopharma Secures $30 Million Financing and Appoints New CEO
- Financing Agreement: Cue Biopharma has entered into a securities purchase agreement with accredited investors, aiming to raise approximately $30 million through a private placement, which will be utilized to advance the company's clinical pipeline and other general corporate purposes, demonstrating strong financing capabilities in the biopharmaceutical sector.
- New CEO Appointment: The company has appointed Shao-Lee Lin as the new Chief Executive Officer, President, and Director, bringing over 25 years of leadership experience in the biopharmaceutical industry, having held executive roles in several prominent companies, which is expected to drive strategic development and innovation within the firm.
- Exclusive License Agreement: Cue Biopharma has signed an exclusive license agreement with Ascendant Health Sciences, granting global rights to develop and commercialize Ascendant-221, potentially yielding up to $676.5 million in milestone payments, thereby enhancing its market position in the treatment of allergic diseases.
- Clinical Trial Plans: Cue Biopharma plans to initiate a global Phase 2b trial for food allergies in the second half of 2026, based on expected results from the Ascendant Health-led Phase 2 study in chronic spontaneous urticaria, which will further propel the product development process.
See More
Cue Biopharma Secures $30 Million Financing and New CEO
- Financing Boosts Cash Flow: Cue Biopharma entered into a securities purchase agreement with accredited investors to raise approximately $30 million in net proceeds through a private placement, significantly enhancing the company's financial position to support its clinical pipeline and general corporate purposes.
- Exclusive License Expands Pipeline: The company announced it has obtained an exclusive license for Ascendant-221 from Ascendant Health Sciences, an experimental drug aimed at treating specific allergic diseases, with mid-stage clinical data expected in the second half of 2026, thereby enriching the company's product pipeline.
- New CEO Appointment: Shao-Lee Lin has been appointed as the new President and CEO, previously raising over $1 billion and taking ACELYRIN public, indicating her leadership could drive Cue Biopharma's strategic growth.
- Positive Market Reaction: Following the financing and leadership changes, Cue Biopharma's shares surged nearly 100% in after-hours trading, reflecting strong investor confidence in the company's future, despite a 35% decline in stock price over the past year.
See More
Cue Biopharma Announces 1-for-30 Reverse Stock Split
- Reverse Stock Split Announcement: Cue Biopharma has announced a 1-for-30 reverse stock split effective April 23, 2026, aimed at boosting its stock price to comply with Nasdaq Capital Market listing rules, thereby enhancing the company's compliance and attractiveness in the capital market.
- Significant Share Reduction: Post-split, the total shares will decrease sharply from approximately 97.7 million to about 3.3 million, maintaining overall company value despite the drastic reduction in share count, which may impact investor ownership structure and market liquidity.
- Trading Adjustments: Starting April 24, 2026, CUE stock will trade on a split-adjusted basis, with all stock options, warrants, and equity plans adjusted accordingly to ensure investor rights are protected under the new structure.
- Negative Market Reaction: Following the reverse split announcement, CUE's stock price plummeted by about 25% to approximately $0.51, indicating market concerns regarding the decision, which could affect the company's future financing capabilities and investor confidence.
See More
