Arbutus Biopharma announces Q3 earnings per share of 4 cents, below consensus estimate of 5 cents.
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Nov 13 2025
0mins
Q3 Revenue Performance: Arbutus reported Q3 revenue of $529k, significantly below the consensus estimate of $1.31M, highlighting a need for strategic focus.
Imdusiran Clinical Data: The company is analyzing clinical data for imdusiran, noting that 46% of Phase 2a patients were able to discontinue treatment, with many achieving long-term functional cures.
Sustained Benefits: Imdusiran has shown sustained benefits in chronic hepatitis B patients across various baseline conditions, indicating its potential effectiveness.
Commitment to Development: Arbutus remains dedicated to accelerating the development and potential approval of imdusiran as part of its strategic priorities.
Discover Tomorrow's Bullish Stocks Today
Receive free daily stock recommendations and professional analysis to optimize your portfolio's potential.
Sign up now to unlock expert insights and stay one step ahead of the market trends.
Analyst Views on ABUS
About ABUS
Arbutus Biopharma Corporation is a clinical-stage biopharmaceutical company focused on infectious disease. The Company is developing imdusiran (AB-729), its proprietary, conjugated GalNAc, subcutaneously delivered RNAi therapeutic, and AB-101, its proprietary oral PD-L1 inhibitor, for the treatment of chronic hepatitis B (cHBV). Its HBV product pipeline includes Imdusiran and AB-101. Its pipeline includes two product candidates that target various steps in the HBV viral lifecycle and consists of various programs: RNAi therapeutic (imdusiran, AB-729) and Oral PD-L1 Inhibitor (AB-101). RNAi therapeutics utilize a natural pathway within cells to silence genes by eliminating the disease-causing proteins that they code for. PD-L1 inhibitors complement its pipeline of agents and could potentially be a part of a combination therapy for the treatment of HBV by reawakening the immune system.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Health Care Stocks Decline as NYSE Health Care Index Eases 0.5%
- Overall Decline in Health Care Stocks: Late Friday afternoon, health care stocks broadly declined, with the NYSE Health Care Index easing 0.5%, reflecting a weakening market confidence in the sector that could impact short-term investor decisions.
- Market Sentiment Fluctuations: The drop in health care stocks may be linked to overall market sentiment fluctuations, as increased uncertainty regarding economic prospects leads to capital outflows from the health sector, affecting industry capital flows.
- Investor Focus Shift: As health care stocks decline, investors may reassess their portfolios, considering reallocating funds to other sectors with greater growth potential, which could impact capital inflows into the health industry.
- Uncertain Future Outlook: The short-term performance of the health care sector may be influenced by policy changes and market dynamics, necessitating investors to closely monitor relevant policies and market trends to make timely investment decisions.
Continue Reading
Arbutus Biopharma (ABUS) Patent Revocation Leads to 18% Stock Crash
- Patent Revocation Impact: The European Patent Office revoked Arbutus's EP 2279254 patent on January 15, causing its stock to plummet over 18% on Friday, marking the largest intraday decline since July 2020, indicating market concerns about the company's future legal standing.
- Legal Response Plan: Arbutus plans to seek a review from the Enlarged Board of Appeal, asserting that the ruling will not affect its patent infringement cases against Moderna in the U.S., Canada, and Japan, demonstrating its confidence in ongoing legal battles.
- Market Reaction: Despite the sharp decline in stock price, retail sentiment on Stocktwits shifted from bearish to bullish, with some users viewing the drop as an opportunity to establish new positions, reflecting divergent views on the company's long-term prospects.
- Competitor Dynamics: While Arbutus's stock fell, Moderna's shares rose by 7%, and Merck's fell by 2%, highlighting varying market reactions to competitors that could influence Arbutus's competitive position moving forward.
Continue Reading