Ardelyx Reports $274M IBSRELA Revenue in 2025, Up 73%
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 08 2026
0mins
Source: NASDAQ.COM
- Significant Revenue Growth: Ardelyx's IBSRELA generated $274 million in 2025, a 73% increase from $158.3 million in 2024, indicating strong market demand and acceptance in the irritable bowel syndrome treatment sector.
- Product Performance Contrast: While IBSRELA excelled, XPHOZAH's revenue fell from $160.9 million in 2024 to $104 million in 2025, primarily due to the loss of Medicare Part D coverage, highlighting the substantial impact of healthcare policies on drug sales.
- Optimistic Future Outlook: Ardelyx expects IBSRELA revenue to range between $410 million and $430 million in 2026, representing at least 50% growth over 2025, reflecting the company's confidence in its product's market potential and sustained growth.
- Accelerated R&D Progress: The company has initiated a Phase 3 clinical trial for IBSRELA in chronic idiopathic constipation, expected to complete in the second half of 2027, while advancing the development of a next-generation NHE3 inhibitor, strengthening its strategic foundation for long-term growth.
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Analyst Views on ARDX
Wall Street analysts forecast ARDX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ARDX is 14.33 USD with a low forecast of 10.00 USD and a high forecast of 19.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
6 Analyst Rating
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 7.850
Low
10.00
Averages
14.33
High
19.00
Current: 7.850
Low
10.00
Averages
14.33
High
19.00
About ARDX
Ardelyx, Inc. is a biopharmaceutical company focused on discovering, developing and commercializing first-in-class medicines. The Company has two commercial products approved in the United States: IBSRELA (tenapanor) and XPHOZAH (tenapanor). IBSRELA is a first-in-class NHE3 inhibitor approved by the United States FDA for the treatment of irritable bowel syndrome with constipation in adults. XPHOZAH is a first-in-class phosphate absorption inhibitor approved in the United States to reduce serum phosphorus in adults with chronic kidney disease (CKD) on dialysis as add-on therapy in patients who have an inadequate response to phosphate binders or who are intolerant of any dose of phosphate binder therapy. It has agreements for the development and commercialization of tenapanor outside of the United States. Kyowa Kirin commercializes PHOZEVEL (tenapanor) for hyperphosphatemia in Japan. A New Drug Application for tenapanor for hyperphosphatemia has been approved in China with Fosun Pharma.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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