ZAI LAB Shares Drop Approximately 13% Amid High Trading Volume Following Amgen's Final Analysis of Bemarituzumab Revealing Reduced Survival Benefit
Stock Performance: ZAI LAB's stock opened nearly 7% lower and reached a three-month low of HKD22.64, closing at HKD22.8, down 12.91% with significant trading volume.
Trial Results: The final analysis of the Phase 3 FORTITUDE-101 trial for bemarituzumab in gastric cancer showed a reduced survival benefit compared to previous observations.
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M Stanley Predicts WUXI BIO (02269.HK) Share Price Increase in Next 45 Days, Raises Target Price to $50
Morgan Stanley's Prediction: Morgan Stanley forecasts a 70-80% probability that WUXI BIO's share price will rise in the next 45 days, following a positive profit alert and management guidance indicating accelerated growth in FY2026.
Earnings Forecast Adjustment: The broker has raised its earnings forecasts for WUXI BIO from 2026 to 2030 by 4-10% and increased the target price from $45 to $50, maintaining an Overweight rating.
Recent Stock Performance: WUXI BIO's stock opened 2.71% higher and reached a peak of $44, marking a two-year high, with a trading volume of approximately 24.89 million shares.
Research Services Momentum: The company is experiencing strong momentum in research services, which is expected to enhance profitability through IP-related revenue and recent out-licensing deals with Vertex and ZAI LAB.
Zai Lab to Participate in 44th Annual J.P. Morgan Healthcare Conference on January 13, 2026
- Conference Participation: Zai Lab will participate in the 44th Annual J.P. Morgan Healthcare Conference on January 13, 2026, at 3:00 p.m. PST, showcasing its innovative research in oncology, immunology, and other fields, aiming to enhance its visibility in the biopharmaceutical industry.
- Live Webcast: The event will be streamed live on Zai Lab's Investor Relations page, allowing global investors to stay updated on the company's latest developments, which is expected to bolster investor confidence.
- Replay Availability: An archived replay of the presentation will be available for up to 30 days post-event, ensuring that investors who cannot attend live can still access critical information, thereby enhancing transparency.
- Company Background: Zai Lab is an innovative biopharmaceutical company based in China and the U.S., focused on developing products that address significant unmet medical needs, and this conference will further emphasize its strategic positioning in the global biopharmaceutical market.
Zai Lab Receives NMPA Approval for COBENFY to Treat Schizophrenia
- Innovative Therapy Approval: Zai Lab's COBENFY (xanomeline and trospium chloride) has received approval from China's NMPA, becoming the first new mechanism schizophrenia treatment in over 70 years, marking a significant breakthrough in schizophrenia care.
- Addressing Patient Needs: With approximately 8 million adults in China suffering from schizophrenia and existing treatments offering limited efficacy, COBENFY selectively activates M1 and M4 receptors to provide broader symptom improvement, which is expected to significantly enhance patients' quality of life.
- Clinical Research Support: The NMPA approval is backed by results from a Phase 1 pharmacokinetics study and Phase 3 clinical trials in China, demonstrating COBENFY's effectiveness in improving positive, negative, and cognitive symptoms while avoiding the side effects commonly associated with traditional antipsychotics.
- Enhanced Industry Influence: The inclusion of COBENFY in the China Schizophrenia Prevention and Treatment Guidelines (2025 Edition) not only elevates Zai Lab's standing in the mental health sector but also lays a foundation for future market expansion.
UBS Maintains Buy Rating on ZAI LAB, Lowers Target Price to HKD 20.1
ZAI LAB's Current Performance: ZAI LAB is experiencing challenges that have impacted its recent performance, with a stock price decline of approximately 27% since November 6.
Long-term Growth Potential: Despite current headwinds, UBS remains optimistic about ZAI LAB's long-term growth potential, particularly regarding its key assets like Zoci and ZL-1503.
Attractive Risk-Reward Ratio: UBS believes that the development and expansion potential of ZAI LAB's products are not yet reflected in its stock price, making the risk-reward ratio attractive.
Rating and Target Price Adjustment: UBS has reiterated a Buy rating for ZAI LAB while lowering its target price from HKD33.5 to HKD20.1.
Zai Lab Updates Three Medicines in China's National Reimbursement Drug List
- Drug Renewals: Zai Lab's VYVGART, NUZYRA, and ZEJULA have been successfully renewed in the 2025 National Reimbursement Drug List by China's NHSA, reflecting their strong clinical value and expected to significantly reduce the disease burden on patients.
- Expanded Market Access: With this update, Zai Lab now has six products included in the NRDL, enhancing patient access to high-quality novel medicines and demonstrating the company's ongoing commitment to innovation in pharmaceuticals.
- Addressing Treatment Needs: VYVGART targets anti-AChR antibody-positive patients with generalized myasthenia gravis, NUZYRA is indicated for community-acquired pneumonia and acute bacterial skin infections, while ZEJULA offers maintenance therapy for platinum-sensitive ovarian cancer patients, fulfilling urgent market demands for new therapies in China.
- Strategic Implications: Zai Lab will continue to enhance the accessibility and affordability of its medicines, enabling more patients to benefit from innovative therapies as early as possible, thereby solidifying its leadership position in China's biopharmaceutical market.
<Research>UBS Identifies Chinese Stocks with Greatest Potential for FY26 Earnings Growth (Table)
UBS China Market Strategy Report: UBS has released a report highlighting Buy-rated Chinese stocks with significant potential for earnings growth by FY26, focusing on Hong Kong-listed and ADR-listed companies.
Highlighted Stocks: The report includes stocks such as INNOCARE, CARSGEN-B, ZAI LAB, AKESO, and CANSINOBIO, along with their recent performance and short selling data.
Short Selling Data: The report provides short selling figures for the listed stocks, indicating varying levels of short interest, with ZAI LAB and AKESO showing higher short selling ratios.
Related Market Insights: Additional context is provided by Soochow Securities, which lists the top 10 Hong Kong stocks with the highest net buys and sells by southbound funds in the previous week.
M Stanley Predicts WUXI BIO (02269.HK) Share Price Increase in Next 45 Days, Raises Target Price to $50
Morgan Stanley's Prediction: Morgan Stanley forecasts a 70-80% probability that WUXI BIO's share price will rise in the next 45 days, following a positive profit alert and management guidance indicating accelerated growth in FY2026.
Earnings Forecast Adjustment: The broker has raised its earnings forecasts for WUXI BIO from 2026 to 2030 by 4-10% and increased the target price from $45 to $50, maintaining an Overweight rating.
Recent Stock Performance: WUXI BIO's stock opened 2.71% higher and reached a peak of $44, marking a two-year high, with a trading volume of approximately 24.89 million shares.
Research Services Momentum: The company is experiencing strong momentum in research services, which is expected to enhance profitability through IP-related revenue and recent out-licensing deals with Vertex and ZAI LAB.
Zai Lab to Participate in 44th Annual J.P. Morgan Healthcare Conference on January 13, 2026
- Conference Participation: Zai Lab will participate in the 44th Annual J.P. Morgan Healthcare Conference on January 13, 2026, at 3:00 p.m. PST, showcasing its innovative research in oncology, immunology, and other fields, aiming to enhance its visibility in the biopharmaceutical industry.
- Live Webcast: The event will be streamed live on Zai Lab's Investor Relations page, allowing global investors to stay updated on the company's latest developments, which is expected to bolster investor confidence.
- Replay Availability: An archived replay of the presentation will be available for up to 30 days post-event, ensuring that investors who cannot attend live can still access critical information, thereby enhancing transparency.
- Company Background: Zai Lab is an innovative biopharmaceutical company based in China and the U.S., focused on developing products that address significant unmet medical needs, and this conference will further emphasize its strategic positioning in the global biopharmaceutical market.
Zai Lab Receives NMPA Approval for COBENFY to Treat Schizophrenia
- Innovative Therapy Approval: Zai Lab's COBENFY (xanomeline and trospium chloride) has received approval from China's NMPA, becoming the first new mechanism schizophrenia treatment in over 70 years, marking a significant breakthrough in schizophrenia care.
- Addressing Patient Needs: With approximately 8 million adults in China suffering from schizophrenia and existing treatments offering limited efficacy, COBENFY selectively activates M1 and M4 receptors to provide broader symptom improvement, which is expected to significantly enhance patients' quality of life.
- Clinical Research Support: The NMPA approval is backed by results from a Phase 1 pharmacokinetics study and Phase 3 clinical trials in China, demonstrating COBENFY's effectiveness in improving positive, negative, and cognitive symptoms while avoiding the side effects commonly associated with traditional antipsychotics.
- Enhanced Industry Influence: The inclusion of COBENFY in the China Schizophrenia Prevention and Treatment Guidelines (2025 Edition) not only elevates Zai Lab's standing in the mental health sector but also lays a foundation for future market expansion.
UBS Maintains Buy Rating on ZAI LAB, Lowers Target Price to HKD 20.1
ZAI LAB's Current Performance: ZAI LAB is experiencing challenges that have impacted its recent performance, with a stock price decline of approximately 27% since November 6.
Long-term Growth Potential: Despite current headwinds, UBS remains optimistic about ZAI LAB's long-term growth potential, particularly regarding its key assets like Zoci and ZL-1503.
Attractive Risk-Reward Ratio: UBS believes that the development and expansion potential of ZAI LAB's products are not yet reflected in its stock price, making the risk-reward ratio attractive.
Rating and Target Price Adjustment: UBS has reiterated a Buy rating for ZAI LAB while lowering its target price from HKD33.5 to HKD20.1.
Zai Lab Updates Three Medicines in China's National Reimbursement Drug List
- Drug Renewals: Zai Lab's VYVGART, NUZYRA, and ZEJULA have been successfully renewed in the 2025 National Reimbursement Drug List by China's NHSA, reflecting their strong clinical value and expected to significantly reduce the disease burden on patients.
- Expanded Market Access: With this update, Zai Lab now has six products included in the NRDL, enhancing patient access to high-quality novel medicines and demonstrating the company's ongoing commitment to innovation in pharmaceuticals.
- Addressing Treatment Needs: VYVGART targets anti-AChR antibody-positive patients with generalized myasthenia gravis, NUZYRA is indicated for community-acquired pneumonia and acute bacterial skin infections, while ZEJULA offers maintenance therapy for platinum-sensitive ovarian cancer patients, fulfilling urgent market demands for new therapies in China.
- Strategic Implications: Zai Lab will continue to enhance the accessibility and affordability of its medicines, enabling more patients to benefit from innovative therapies as early as possible, thereby solidifying its leadership position in China's biopharmaceutical market.
<Research>UBS Identifies Chinese Stocks with Greatest Potential for FY26 Earnings Growth (Table)
UBS China Market Strategy Report: UBS has released a report highlighting Buy-rated Chinese stocks with significant potential for earnings growth by FY26, focusing on Hong Kong-listed and ADR-listed companies.
Highlighted Stocks: The report includes stocks such as INNOCARE, CARSGEN-B, ZAI LAB, AKESO, and CANSINOBIO, along with their recent performance and short selling data.
Short Selling Data: The report provides short selling figures for the listed stocks, indicating varying levels of short interest, with ZAI LAB and AKESO showing higher short selling ratios.
Related Market Insights: Additional context is provided by Soochow Securities, which lists the top 10 Hong Kong stocks with the highest net buys and sells by southbound funds in the previous week.
