BriaCell Selected for MSK's 2025 Therapeutics Accelerator Program for Bria-OTS+™ for Cancer
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Aug 13 2025
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Should l Buy BCTX?
Source: Newsfilter
BriaCell's Collaboration with MSK: BriaCell Therapeutics Corp. has been accepted into the Memorial Sloan Kettering Cancer Center's Therapeutics Accelerator 2025 Cohort program to expedite the clinical development of its personalized immunotherapy, Bria-OTS+, for various cancers.
Expertise and Resources Utilization: The partnership will allow BriaCell to leverage MSK's expertise in cancer therapy development and access essential resources, including GMP manufacturing and regulatory support, to enhance the efficacy and safety of their treatment options.
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Analyst Views on BCTX
About BCTX
BriaCell Therapeutics Corp. is a clinical-stage biotechnology company that develops novel immunotherapies to transform cancer care. Bria-IMT, its Phase 3 lead candidate, is a patented, off-the-shelf, cell-based, targeted immunotherapy that activates the patient’s immune system to specifically kill cancer cells without harming other cells. The Company is advancing its Bria-IMT targeted immunotherapy in combination with an immune check point inhibitor (Retifanlimab) in a pivotal Phase 3 study in metastatic breast cancer. It is also developing personalized off-the-shelf immunotherapies, Bria-OTS and Bria-OTS+, which provides a platform technology to develop personalized off-the-shelf immunotherapies for numerous types of cancer, and a soluble CD80 protein therapeutic which act both as a stimulator of the immune system, as well as an immune checkpoint inhibitor. Its pipeline also includes Bria-IMT + CPI, Bria-BRES/BRES+, Bria-PROS+, Bria-LUNG+ and Bria-MEL+.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Clinical Trial Progress: The Bria-IMT regimen continues under Fast Track Designation from the US FDA, expected to offer more effective treatment options for late-stage breast cancer patients, addressing the urgent market need for new therapies.
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- Significant Clinical Efficacy: The Bria-IMT treatment achieved complete resolution of right temporal lobe metastasis in a 66-year-old female patient, who survived 27 months post-enrollment, demonstrating the therapy's potential in heavily pre-treated patients.
- Evidence of Immune Activation: CD8 ImmunoPET imaging revealed a significant increase in CD8+ T cells in the cervical lymph nodes post-Bria-IMT treatment, indicating immune system activation that may contribute to long-term survival.
- Study Scale and Results: Among 54 heavily pre-treated metastatic breast cancer patients, 37 received the Bria-IMT regimen, with no reported treatment discontinuations related to Bria-IMT to date, indicating good safety and tolerability of the therapy.
- Future Research Prospects: The ongoing Phase 3 clinical trial (NCT06072612) by BriaCell will further validate the efficacy of Bria-IMT, potentially bringing new hope to cancer treatment.
See More
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- Impressive Survival Data: As of the latest assessment, nine patients treated with Bria-IMT since 2022 have survived over 18 months, significantly exceeding benchmarks for standard therapies, indicating the potential efficacy of this treatment.
- Strong Treatment Continuity: No Bria-IMT-related discontinuations have been reported to date, suggesting good tolerability of the regimen among patients, which may provide new treatment options for heavily pre-treated individuals.
- Clinical Trial Progress: The Bria-IMT regimen continues under Fast Track Designation from the US FDA, expected to offer more effective treatment options for late-stage breast cancer patients, addressing the urgent market need for new therapies.
- Future Research Directions: BriaCell's ongoing pivotal Phase 3 study will focus on overall survival as its primary endpoint, aiming to further validate the efficacy of Bria-IMT and promote its broader acceptance in clinical applications.
See More
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- Tech Stock Decline: Information technology stocks fell by 1.3% on Wednesday, reflecting market concerns over the tech sector, which may affect investor confidence and lead to capital outflows.
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- Market Dynamics: While U.S. stocks traded lower overall, with the Nasdaq Composite falling over 100 points, energy stocks rose by 0.9%, indicating a divergence in market performance that may present investors with opportunities to reassess their portfolios.
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- Trip.com Investigation Impact: Trip.com Group confirmed it is under investigation by China's SAMR for potential anti-monopoly violations, resulting in a 9.3% decline in its pre-market stock price, which may adversely affect its market performance and investor confidence.
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- Public Offering Details: BriaCell Therapeutics announced a public offering of 5.367 million units priced at $5.59 each, aiming for gross proceeds of approximately $30 million, which will fund working capital and general corporate purposes.
- Warrant Information: Each unit consists of one common share and one warrant, the latter allowing purchase of common shares at an exercise price of $6.93, expiring five years post-issuance, enhancing potential returns for investors.
- Stock Price Impact: Following the announcement, BCTX's stock plummeted 54.12% to $5.01, reflecting a highly negative market reaction despite a previous surge to $12.10 due to positive results in treating breast cancer patients.
- Future Trading Arrangements: The warrants have been approved for listing on the Nasdaq Capital Market, expected to begin trading under the symbol
See More
