Amgen's Phase 3 Trial Success Leads to Viridian Stock Plunge
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Apr 06 2026
0mins
Should l Buy VRDN?
Source: stocktwits
- Amgen Trial Results: Amgen's Phase 3 trial achieved its primary goal, with 77% of patients showing significant improvement in eye bulging, indicating the effectiveness of its drug Tepezza for thyroid eye disease, which could positively impact market dynamics.
- Viridian Drug Performance: Viridian's Elegrobar reduced eye bulging by approximately 54% and 63% over four and eight weeks, respectively, although its efficacy is lower than Amgen's; however, its simpler subcutaneous injection method may provide a competitive edge in the market.
- Stock Price Volatility: Viridian's shares plummeted 23% on Monday, hitting the lowest point since June 3, 2025, reflecting market disappointment over its Phase 3 trial results, particularly due to limited inflammation improvement and reports of tinnitus.
- Market Sentiment Shift: Despite the stock's decline, retail sentiment on Stocktwits shifted from 'extremely bullish' to 'bullish', indicating some market participants expect a rebound, with predictions of the stock rising to $25 by the end of the week.
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Analyst Views on VRDN
Wall Street analysts forecast VRDN stock price to rise
17 Analyst Rating
17 Buy
0 Hold
0 Sell
Strong Buy
Current: 14.660
Low
14.20
Averages
41.71
High
61.00
Current: 14.660
Low
14.20
Averages
41.71
High
61.00
About VRDN
Viridian Therapeutics, Inc. is a biopharmaceutical company focused on engineering and developing potential medicines for patients with serious and rare diseases. The Company is advancing multiple candidates in the clinic for the treatment of patients with thyroid eye disease (TED). The Company is conducting two global Phase 3 clinical trials (THRIVE and THRIVE-2) to evaluate the safety and efficacy of veligrotug in patients with active and chronic TED. It is also conducting two global Phase 3 clinical trials, REVEAL-1 and REVEAL-2, to evaluate the efficacy and safety of VRDN-003 in patients. Its advanced program, veligrotug, is a differentiated humanized monoclonal antibody targeting IGF-1R intravenously administered for the treatment of TED. In addition to its TED portfolio, the Company is advancing a novel portfolio of neonatal Fc receptor (FcRn) inhibitors, including VRDN-006 and VRDN-008, which has the potential to be developed in multiple autoimmune diseases.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Amgen Trial Results: Amgen's Phase 3 trial achieved its primary goal, with 77% of patients showing significant improvement in eye bulging, indicating the effectiveness of its drug Tepezza for thyroid eye disease, which could positively impact market dynamics.
- Viridian Drug Performance: Viridian's Elegrobar reduced eye bulging by approximately 54% and 63% over four and eight weeks, respectively, although its efficacy is lower than Amgen's; however, its simpler subcutaneous injection method may provide a competitive edge in the market.
- Stock Price Volatility: Viridian's shares plummeted 23% on Monday, hitting the lowest point since June 3, 2025, reflecting market disappointment over its Phase 3 trial results, particularly due to limited inflammation improvement and reports of tinnitus.
- Market Sentiment Shift: Despite the stock's decline, retail sentiment on Stocktwits shifted from 'extremely bullish' to 'bullish', indicating some market participants expect a rebound, with predictions of the stock rising to $25 by the end of the week.
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- OraSure Options Volume: OraSure Technologies Inc. experienced options trading volume of 3,510 contracts, representing approximately 351,000 shares, which is about 62.6% of its average daily trading volume of 560,775 shares over the past month, indicating heightened market interest in its future performance.
- High Demand for Call Options: Notably, the $2.50 strike call option expiring on April 17, 2026, saw trading of 3,500 contracts today, representing around 350,000 shares, suggesting investor optimism regarding OraSure's prospects.
- Viridian Options Volume: Viridian Therapeutics Inc. recorded options trading volume of 14,194 contracts, equating to approximately 1.4 million shares, or about 61% of its average daily trading volume of 2.3 million shares over the past month, reflecting strong investor interest in the company.
- Active Trading of Put Options: Particularly, the $14 strike put option expiring on May 15, 2026, has seen trading of 5,002 contracts today, representing approximately 500,200 shares, indicating market concerns regarding potential risks facing Viridian in the future.
See More
Amgen's Phase 3 Trial Success Leads to Viridian Stock Plunge
- Amgen Trial Results: Amgen's Phase 3 trial achieved its primary goal, with 77% of patients showing significant improvement in eye bulging, indicating the effectiveness of its drug Tepezza for thyroid eye disease, which could positively impact market dynamics.
- Viridian Drug Performance: Viridian's Elegrobar reduced eye bulging by approximately 54% and 63% over four and eight weeks, respectively, although its efficacy is lower than Amgen's; however, its simpler subcutaneous injection method may provide a competitive edge in the market.
- Stock Price Volatility: Viridian's shares plummeted 23% on Monday, hitting the lowest point since June 3, 2025, reflecting market disappointment over its Phase 3 trial results, particularly due to limited inflammation improvement and reports of tinnitus.
- Market Sentiment Shift: Despite the stock's decline, retail sentiment on Stocktwits shifted from 'extremely bullish' to 'bullish', indicating some market participants expect a rebound, with predictions of the stock rising to $25 by the end of the week.
See More
Viridian Therapeutics Shares Plummet: The Connection to an Amgen Study Explained.
- Viridian Therapeutics Stock Reaction: Viridian Therapeutics' stock experienced a decline on Monday.
- Amgen's Phase 3 Trial Results: The drop followed Amgen's announcement of positive results from a Phase 3 trial for a new treatment targeting thyroid eye disease.
See More
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- Deadline Pressure: The optimism is linked to a looming Tuesday evening deadline concerning threatened strikes on power plants by the president.
See More
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- ARS Pharma Expands Neffy Label: ARS Pharmaceuticals received FDA approval to update the Neffy 1mg label, removing age restrictions for individuals weighing over 33 lbs, which is expected to significantly boost market demand and enhance the company's competitive edge in allergy treatment.
- Novo Nordisk Wins Approval for Awiqli: Novo Nordisk's Awiqli (insulin icodec-abae) received FDA approval as the first once-weekly basal insulin, with a U.S. launch planned for 2H 2026, strengthening the company's leadership in diabetes care.
- Biogen Acquires Apellis: Biogen has agreed to acquire Apellis for $41 per share, valuing the deal at approximately $5.6 billion, which is expected to enhance its market share in immunology and rare diseases while driving future revenue growth.
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