RNAZ News & Events

TransCode Therapeutics announced the initiation of its Phase 2a clinical trial. The study is to evaluate TransCode's lead therapeutic candidate, TTX-MC138, in patients with circulating tumor DNA positive colorectal cancer following curative-intent therapy. The trial is being conducted in collaboration with Quantum Leap Healthcare Collaborative, sponsor of the PRE-I-SPY clinical trial platform. The trial builds on growing clinical and scientific momentum supporting ctDNA-guided strategies targeting minimal residual disease in colorectal cancer. The Phase 2a clinical trial is expected to enroll up to 45 patients with colorectal cancer who have completed standard curative-intent therapy and have no radiographic evidence of disease, but remain or become ctDNA-positive, indicating the presence of minimal residual disease.

Transcode Therapeutics files to sell 15.96M shares of common stock for holders

TransCode announced the execution of a sponsored research agreement with Michigan State University. The agreement is designed to accelerate development of TransCode's pipeline candidates from the laboratory into clinical development. Research conducted at MSU will also focus on evaluation of TransCode's lead therapeutic candidate, TTX-MC138, in combination withSeviprotimut-L for potential synergies and in combination with standard-of-care therapies. TransCode acquired Seviprotimut-L through its acquisition of the parent company of Polynoma.