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PLSE Should I Buy

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Intellectia

Should You Buy Pulse Biosciences Inc (PLSE) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
22.100
1 Day change
-1.34%
52 Week Range
26.300
Analysis Updated At
2026/03/20
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Pulse Biosciences Inc (PLSE) is not a strong buy for a beginner investor with a long-term strategy at this time. While the company has potential catalysts in its pipeline, such as the nPulse Cardiac Catheter program and positive feasibility study results, the financial performance remains weak with declining net income and EPS. Insider selling and lack of significant hedge fund activity further weaken the case for immediate investment. A hold position is recommended until more concrete financial improvements or broader adoption of its technology are observed.

Technical Analysis

The technical indicators are mixed. The MACD is positive and expanding, suggesting bullish momentum. Moving averages are bullish (SMA_5 > SMA_20 > SMA_200), and the pre-market price is near the R1 resistance level of 22.643. However, the RSI of 77.685 is in the neutral zone, not providing a clear signal. The stock's historical trend suggests limited short-term upside potential.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
6
Buy
8

Positive Catalysts

  • Positive feasibility study results for the nPulse Cardiac Catheter program, showing high efficacy in treating Atrial Fibrillation.

  • FDA approval to commence pivotal IDE study for paroxysmal-AF.

  • Plans to present new clinical data at the 2026 Heart Rhythm Conference.

Neutral/Negative Catalysts

  • Insiders are selling heavily, with a 3340.02% increase in selling activity over the last month.

  • Weak financial performance in Q4 2025, with declining net income (-10.07% YoY) and EPS (-16.13% YoY).

  • Lack of significant hedge fund activity and no recent congress trading data.

Financial Performance

In Q4 2025, revenue remained flat at $264,000, while net income dropped to -$17.43M (-10.07% YoY) and EPS fell to -$0.26 (-16.13% YoY). Gross margin remained unchanged at 1.52%. The financials indicate weak profitability and growth.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are optimistic about PLSE, with Oppenheimer and Mizuho raising their price targets to $30 and maintaining Outperform ratings. Analysts highlight strong technology adoption potential and positive feasibility study results. However, they caution that larger trials are needed to confirm efficacy.

Wall Street analysts forecast PLSE stock price to fall
1 Analyst Rating
Wall Street analysts forecast PLSE stock price to fall
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 22.400
sliders
Low
22
Averages
22
High
22
Current: 22.400
sliders
Low
22
Averages
22
High
22
Oppenheimer
Suraj Kalia
Outperform
maintain
$22 -> $30
AI Analysis
2026-02-20
Reason
Oppenheimer
Suraj Kalia
Price Target
$22 -> $30
AI Analysis
2026-02-20
maintain
Outperform
Reason
Oppenheimer analyst Suraj Kalia raised the firm's price target on Pulse Biosciences to $30 from $22 and keeps an Outperform rating on the shares. The firm notes the company reported Q4 revenues of $0.3M vs. its $0.3M estimate, following soft-tissue ablation platform launch in Q3 2025. Pulse received FDA approval to commence pivotal IDE study of nPulse Cardiac Catheter for paroxysmal-AF, to begin enrollment in next few months, completing Q4 2026. This follows feasibility study data, and while encouraging to say the least, results require confirmation in larger trials, Oppenheimer adds.
Mizuho
Outperform
maintain
$25 -> $30
2026-02-06
Reason
Mizuho
Price Target
$25 -> $30
2026-02-06
maintain
Outperform
Reason
Mizuho raised the firm's price target on Pulse Biosciences to $30 from $25 and keeps an Outperform rating on the shares. The firm cites the company's "strong showing" 2026 AF Symposium for the target boost.
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