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PLSE Should I Buy

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Intellectia

Should You Buy Pulse Biosciences Inc (PLSE) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
20.830
1 Day change
-1.61%
52 Week Range
26.300
Analysis Updated At
2026/04/24
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Pulse Biosciences Inc (PLSE) is not a strong buy at this moment for a beginner investor with a long-term strategy. While the stock has positive technical indicators and bullish analyst ratings, the company's financial performance is weak, with declining net income and EPS. Additionally, insider selling activity has significantly increased, which raises concerns about confidence in the stock. The lack of recent news catalysts and no significant trading signals further supports a hold recommendation.

Technical Analysis

The technical indicators show a bullish trend with MACD positively expanding, RSI in the neutral zone, and moving averages indicating upward momentum (SMA_5 > SMA_20 > SMA_200). The pre-market price is near the R1 resistance level of 24.16, suggesting limited immediate upside potential.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
8
Buy
4

Positive Catalysts

  • Bullish analyst ratings with increased price targets from Oppenheimer and Mizuho, citing strong product potential and FDA approval for pivotal IDE study.

  • Encouraging feasibility study data for the nPulse Cardiac Catheter.

Neutral/Negative Catalysts

  • Significant insider selling activity, with a 3340.02% increase in the last month.

  • Weak financial performance in Q4 2025, with declining net income (-10.07% YoY) and EPS (-16.13% YoY).

  • No recent news or significant trading trends to drive short-term momentum.

Financial Performance

In Q4 2025, revenue remained flat at $264,000 YoY. Net income dropped to -$17.43M (-10.07% YoY), and EPS declined to -0.26 (-16.13% YoY). Gross margin remained unchanged at 1.52%. The financials indicate weak growth and profitability trends.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are bullish on PLSE, with Oppenheimer and Mizuho raising price targets to $30 and maintaining Outperform ratings. The positive outlook is driven by strong product potential and FDA approval for a pivotal IDE study.

Wall Street analysts forecast PLSE stock price to rise
1 Analyst Rating
Wall Street analysts forecast PLSE stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 21.170
sliders
Low
22
Averages
22
High
22
Current: 21.170
sliders
Low
22
Averages
22
High
22
Oppenheimer
Suraj Kalia
Outperform
maintain
$22 -> $30
AI Analysis
2026-02-20
Reason
Oppenheimer
Suraj Kalia
Price Target
$22 -> $30
AI Analysis
2026-02-20
maintain
Outperform
Reason
Oppenheimer analyst Suraj Kalia raised the firm's price target on Pulse Biosciences to $30 from $22 and keeps an Outperform rating on the shares. The firm notes the company reported Q4 revenues of $0.3M vs. its $0.3M estimate, following soft-tissue ablation platform launch in Q3 2025. Pulse received FDA approval to commence pivotal IDE study of nPulse Cardiac Catheter for paroxysmal-AF, to begin enrollment in next few months, completing Q4 2026. This follows feasibility study data, and while encouraging to say the least, results require confirmation in larger trials, Oppenheimer adds.
Mizuho
Outperform
maintain
$25 -> $30
2026-02-06
Reason
Mizuho
Price Target
$25 -> $30
2026-02-06
maintain
Outperform
Reason
Mizuho raised the firm's price target on Pulse Biosciences to $30 from $25 and keeps an Outperform rating on the shares. The firm cites the company's "strong showing" 2026 AF Symposium for the target boost.
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