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CGEN Should I Buy

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Intellectia

Should You Buy Compugen Ltd (CGEN) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
3.100
1 Day change
6.16%
52 Week Range
3.230
Analysis Updated At
2026/04/24
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Compugen Ltd (CGEN) does not present a strong buy opportunity for a beginner investor with a long-term horizon and $50,000-$100,000 available for investment. While the stock has shown a bullish technical setup and has a promising analyst rating with a $6 price target, the lack of recent news, insider selling trends, and mixed financial performance (revenue growth but significant net income and EPS declines) suggest caution. Additionally, no strong trading signals or congress trading data are available to support a buy decision.

Technical Analysis

The technical indicators suggest a bullish trend with SMA_5 > SMA_20 > SMA_200 and a MACD histogram above 0. However, RSI is in the neutral zone, and the stock is trading near its resistance level (R1: 2.965). The stock's recent price movements indicate limited upside in the short term.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
5
Buy
9

Positive Catalysts

  • Analyst Chad Messer initiated coverage with a Buy rating and a $6 price target, citing Compugen's unique TIGIT design and partnership with AstraZeneca.

  • Revenue increased significantly (4477.29% YoY) in Q4 2025, showing potential for growth.

Neutral/Negative Catalysts

  • Insiders have been selling shares, with a 177.02% increase in selling activity over the last month.

  • Net income and EPS have declined sharply (-1029.30% and -942.86% YoY, respectively).

  • No recent news or congress trading data to act as a catalyst.

Financial Performance

In Q4 2025, revenue increased significantly by 4477.29% YoY, and gross margin improved to 94.75%. However, net income dropped by -1029.30%, and EPS fell by -942.86%, indicating profitability challenges.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Lake Street analyst Chad Messer initiated coverage with a Buy rating and a $6 price target, highlighting the company's innovative TIGIT design and collaboration with AstraZeneca. However, no other recent analyst updates or price target changes are available.

Wall Street analysts forecast CGEN stock price to rise
2 Analyst Rating
Wall Street analysts forecast CGEN stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 2.920
sliders
Low
4
Averages
4
High
4
Current: 2.920
sliders
Low
4
Averages
4
High
4
Lake Street
Chad Messer
Buy
initiated
$6
AI Analysis
2026-04-07
Reason
Lake Street
Chad Messer
Price Target
$6
AI Analysis
2026-04-07
initiated
Buy
Reason
Lake Street analyst Chad Messer initiated coverage of Compugen (CGEN) with a Buy rating and $6 price target. After high-profile Phase 3 failures from Roche (RHHBY), Merck (MRK), Gilead (GILD), and GSK (GSK), Compugen and AstraZeneca (AZN) now remain the only players with a TIGIT design that addresses the class's historical flaws, the analyst tells investors. Compugen's TIGIT component utilizes a unique Fc-reduced architecture engineered to maintain high affinity while preventing the depletion of effector T-cells, "the very killers needed to fight the tumor," the analyst added.
H.C. Wainwright
NULL -> Buy
initiated
$4
2026-01-07
Reason
H.C. Wainwright
Price Target
$4
2026-01-07
initiated
NULL -> Buy
Reason
H.C. Wainwright initiated coverage of Compugen with a Buy rating and $4 price target. The firm says the company's immuno-oncology pipeline "offers multiple shots on goal." Compugen holds mid-single-digit royalty rights and AstraZeneca estimates peak sales potential of more than $5B, implying a peak royalty stream of over $200M, the analyst tells investors in a research note.
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