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VSTM Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

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High
4.570
Open
4.100
VWAP
4.38
Vol
2.97M
Mkt Cap
395.43M
Low
4.070
Amount
13.00M
EV/EBITDA(TTM)
--
Total Shares
87.87M
EV
296.42M
EV/OCF(TTM)
--
P/S(TTM)
--
Verastem, Inc. is a late-stage development biopharmaceutical company, which focuses on the development and commercialization of new medicines to improve the lives of patients diagnosed with ras sarcoma (RAS)/ mitogen-activated pathway kinase (MAPK) pathway-driven cancers. Its product candidates include avutometinib and defactinib. Avutometinib is an oral RAF/MEK clamp that inhibits MEK1/2 kinase activities and induces inactive complexes of MEK with A-Raf proto-oncogene, potentially serine/threonine kinase (ARAF), B-Raf proto-oncogene serine/threonine kinase (BRAF) and C-raf proto-oncogene serine/threonine kinase, creating antitumor response through maximal RAS/MAPK pathway inhibition. Defactinib is an oral, selective inhibitor of FAK and proline-rich tyrosine kinase (PYK2), the two members of the focal adhesion kinase family of non-receptor protein tyrosine kinases. FAK and PYK2 integrate signals from integrin and growth factor receptors to regulate cell proliferation.
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Events Timeline

(ET)
2026-06-23
16:30:00
Verastem Oncology Reports Positive Preliminary Data for VS-7375 Clinical Trial
select
2026-06-17 (ET)
2026-06-17
08:00:00
Verastem Oncology Updates RAMP 205 Trial Results
select
2026-06-16 (ET)
2026-06-16
16:30:00
Verastem Oncology Begins TARGET-D 201 Trial
select
2026-06-03 (ET)
2026-06-03
16:30:00
Verastem Stock Up 11% to $4.00 After FDA Fast Track Designation for VS-7375
select
2026-06-03
16:10:00
Verastem Receives FDA Fast Track Designation for VS-7375
select
2026-05-26 (ET)
2026-05-26
07:40:00
Verastem Oncology Appoints Michael Bailey to Board of Directors
select

News

Newsfilter
2.0
06-17Newsfilter
Verastem Oncology Reports Positive RAMP 205 Trial Results
  • Clinical Trial Results: In the RAMP 205 trial, 29 patients received a combination of avutometinib and defactinib with chemotherapy, achieving an 86% overall survival rate at six months, indicating the potential of this combination as a new treatment option for metastatic pancreatic cancer.
  • Tumor Shrinkage Rate: Among patients at the recommended dose, 83% experienced tumor shrinkage, demonstrating the effectiveness of the treatment combination in inhibiting tumor growth, which may improve patient prognosis and quality of life.
  • Research Support: Verastem received a $3.8 million grant from PanCAN to accelerate the development of this treatment combination, underscoring the commitment to pancreatic cancer research and laying the groundwork for future clinical applications.
  • Future Development Directions: Verastem plans to continue evaluating the potential role of this treatment combination in metastatic pancreatic cancer and explore opportunities for strategic collaborations to advance the development and application of new therapies.
stocktwits
9.0
06-04stocktwits
Verastem's VS-7375 Receives FDA Fast Track Designation for Lung Cancer Treatment
  • FDA Fast Track Approval: Verastem's oral drug VS-7375 has received Fast Track designation from the FDA, aimed at expediting its development as a treatment for advanced non-small cell lung cancer driven by specific genetic mutations, which is expected to significantly reduce patient wait times.
  • Significant Market Potential: The KRAS G12D mutation occurs in about 5% of non-small cell lung cancer cases, translating to over 8,000 patients diagnosed annually in the U.S. who currently face poor treatment responses, indicating that the success of VS-7375 could transform their treatment landscape.
  • Clinical Trial Progress: Verastem is conducting multiple clinical trials, including a mid-stage registration-directed trial focused on advanced lung cancer patients who have received one or two prior lines of treatment, with early safety and activity data expected in the first half of 2026.
  • Investor Sentiment Shift: Following the FDA approval, retail investor sentiment around VSTM stock has shifted from 'bearish' to 'bullish', with message volume on Stocktwits significantly increasing, reflecting market optimism regarding the drug's future potential.
Newsfilter
9.0
06-03Newsfilter
Verastem Receives FDA Fast Track Designation for VS-7375
  • Clinical Trial Progress: Verastem is conducting the TARGET-D 101 clinical trial to evaluate the safety and efficacy of VS-7375 in patients with advanced KRAS G12D-mutated tumors, with early data updates expected in the first half of 2026, indicating the drug's potential in treatment.
  • FDA Fast Track Designation: The FDA has granted Fast Track Designation to VS-7375 for KRAS G12D-mutated non-small cell lung cancer, highlighting the drug's significant potential to address unmet medical needs and improve patient outcomes.
  • Strong Market Demand: Non-small cell lung cancer is the most prevalent type of lung cancer in the U.S., with over 8,000 patients diagnosed with KRAS G12D mutations annually, showcasing the market potential of VS-7375 and its significant impact on patients.
  • Multi-Center Study Initiation: The TARGET-D 202 clinical trial has been initiated to evaluate a 900mg once-daily dose of VS-7375, further validating its efficacy in advanced non-small cell lung cancer patients who have received one to two prior lines of therapy, advancing the development of new therapies.
Newsfilter
5.0
05-26Newsfilter
Verastem Oncology Appoints New Board Member
  • New Board Member: Verastem Oncology has appointed Michael P. Bailey to its Board of Directors, bringing over three decades of experience in global pharmaceuticals and biotechnology, which is expected to significantly support the company's future growth.
  • Strategic Development Focus: Bailey's appointment comes as Verastem enters a new phase with AVMAPKI® FAKZYNJA® CO-PACK and VS-7375, a potential best-in-class oral KRAS G12D inhibitor aimed at improving the quality of life for patients with rare cancers lacking effective treatments.
  • Rich Leadership Experience: Currently the CEO of AVEO Pharmaceuticals, Bailey has held executive roles in several pharmaceutical companies, notably launching ERBITUX® during his tenure at ImClone Systems, providing valuable insights for Verastem's innovative pipeline.
  • Acknowledgment of Former Director: The company expressed gratitude for Robert Gagnon's contributions during his tenure on the board, highlighting the importance of board member transitions in maintaining competitiveness in the rapidly evolving biopharmaceutical industry.
Newsfilter
1.0
05-12Newsfilter
Verastem Oncology Announces Investor Conference Schedule
  • Investor Conference Schedule: Verastem Oncology is set to participate in the HCW 4th Annual BioConnect Investor Conference on May 19, 2026, and the RBC Global Healthcare Conference on May 20, 2026, showcasing advancements in RAS/MAPK pathway-driven cancers, which is expected to attract investor interest and enhance company visibility.
  • Webcast Availability: The company will provide live webcasts of the presentations on its website under the 'Events & Presentations' section, with replays available for approximately 90 days post-event, ensuring that investors unable to attend live can still access critical information.
  • Product Market Positioning: Verastem Oncology focuses on developing and commercializing new medicines, particularly for patients with RAS/MAPK pathway-driven cancers, with existing products like AVMAPKI® and FAKZYNJA® CO-PACK in the market, indicating the company's potential in the biopharmaceutical sector.
  • R&D Pipeline Focus: The company's pipeline emphasizes novel small molecule drugs that inhibit critical signaling pathways promoting cancer cell survival and tumor growth, including RAF/MEK inhibition, FAK inhibition, and KRAS G12D inhibition, showcasing its innovative capabilities in cancer treatment.
Newsfilter
8.5
05-08Newsfilter
Launch of LGSOC Resource Guide to Support Patients
  • Resource Integration: The STAAR Low-Grade Serous Ovarian Cancer Foundation and Verastem Oncology have launched the LGSOC Resource Guide, designed to provide comprehensive educational materials and community resources for patients and caregivers dealing with this rare form of ovarian cancer, thereby addressing significant informational gaps.
  • Patient Engagement: The guide's release coincides with World Ovarian Cancer Day, emphasizing the critical role of patients in treatment decision-making, which helps them transition from feeling powerless to becoming active participants in their care, ultimately enhancing their quality of life and treatment confidence.
  • FDA Interaction: In 2023, STAAR held its first-ever Externally-led Patient-Focused Drug Development meeting with the FDA, advancing recognition of LGSOC as a distinct disease requiring dedicated treatment approaches, which facilitated the development of the first FDA-approved treatment for KRAS-mutated recurrent LGSOC.
  • Mental Health Focus: LGSOC patients face significant mental and physical health challenges, and the resource guide offers support information regarding emotional well-being and fertility, aiming to assist patients and their families in obtaining necessary support and information when confronting the disease.
Wall Street analysts forecast VSTM stock price to rise
6 Analyst Rating
Wall Street analysts forecast VSTM stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
14.00
Averages
15.60
High
20.00
Current: 0.000
sliders
Low
14.00
Averages
15.60
High
20.00
Jefferies
Buy
to
Buy
downgrade
$15 -> $8
AI Analysis
2026-06-23
Reason
Jefferies
Price Target
$15 -> $8
AI Analysis
2026-06-23
downgrade
Buy
to
Buy
Reason
Jefferies lowered the firm's price target on Verastem to $8 from $15 and keeps a Buy rating on the shares. The long pitch on Verastem is "growing less attractive" as the space is getting crowded, raising the bar for differentiation, the analyst tells investors.
Mizuho
Graig Suvannavejh
Outperform
to
Outperform
downgrade
$16 -> $14
2026-05-14
Reason
Mizuho
Graig Suvannavejh
Price Target
$16 -> $14
2026-05-14
downgrade
Outperform
to
Outperform
Reason
Mizuho analyst Graig Suvannavejh lowered the firm's price target on Verastem to $14 from $16 and keeps an Outperform rating on the shares. The firm updated the company's model post the Q1 report.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for VSTM
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Valuation Metrics

The current forward P/E ratio for Verastem Inc (VSTM.O) is 0.00, compared to its 5-year average forward P/E of -4.85. For a more detailed relative valuation and DCF analysis to assess Verastem Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.85
Current PE
0.00
Overvalued PE
2.91
Undervalued PE
-12.62

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.22
Current EV/EBITDA
-0.74
Overvalued EV/EBITDA
0.38
Undervalued EV/EBITDA
-0.81

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
412.73
Current PS
2.21
Overvalued PS
1960.14
Undervalued PS
-1134.68

Financials

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Quarterly

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Whales Holding VSTM

L
Logos Global Management, L.P.
Holding
VSTM
+24.20%
3M Return
D
Deep Track Capital, LP
Holding
VSTM
+22.94%
3M Return
A
Armistice Capital LLC
Holding
VSTM
+16.42%
3M Return
N
Nantahala Capital Management, LLC
Holding
VSTM
+16.04%
3M Return
T
Tang Capital Management, LLC
Holding
VSTM
+10.35%
3M Return
R
RTW Investments, LP
Holding
VSTM
+8.92%
3M Return

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Frequently Asked Questions

What is Verastem Inc (VSTM) stock price today?

The current price of VSTM is 4.5 USD — it has increased 9.76

What is Verastem Inc (VSTM)'s business?

Verastem, Inc. is a late-stage development biopharmaceutical company, which focuses on the development and commercialization of new medicines to improve the lives of patients diagnosed with ras sarcoma (RAS)/ mitogen-activated pathway kinase (MAPK) pathway-driven cancers. Its product candidates include avutometinib and defactinib. Avutometinib is an oral RAF/MEK clamp that inhibits MEK1/2 kinase activities and induces inactive complexes of MEK with A-Raf proto-oncogene, potentially serine/threonine kinase (ARAF), B-Raf proto-oncogene serine/threonine kinase (BRAF) and C-raf proto-oncogene serine/threonine kinase, creating antitumor response through maximal RAS/MAPK pathway inhibition. Defactinib is an oral, selective inhibitor of FAK and proline-rich tyrosine kinase (PYK2), the two members of the focal adhesion kinase family of non-receptor protein tyrosine kinases. FAK and PYK2 integrate signals from integrin and growth factor receptors to regulate cell proliferation.

What is the price predicton of VSTM Stock?

Wall Street analysts forecast VSTM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for VSTM is15.60 USD with a low forecast of 14.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Verastem Inc (VSTM)'s revenue for the last quarter?

Verastem Inc revenue for the last quarter amounts to 18.67M USD, decreased

What is Verastem Inc (VSTM)'s earnings per share (EPS) for the last quarter?

Verastem Inc. EPS for the last quarter amounts to -0.37 USD, decreased -61.46

How many employees does Verastem Inc (VSTM). have?

Verastem Inc (VSTM) has 102 emplpoyees as of July 05 2026.

What is Verastem Inc (VSTM) market cap?

Today VSTM has the market capitalization of 395.43M USD.