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VSTM Overview

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0.000(0.000%)Aft-market
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0.000
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
4.340
Open
4.090
VWAP
4.20
Vol
2.94M
Mkt Cap
362.92M
Low
4.000
Amount
12.37M
EV/EBITDA(TTM)
--
Total Shares
87.87M
EV
265.66M
EV/OCF(TTM)
--
P/S(TTM)
--
Verastem, Inc. is a late-stage development biopharmaceutical company, which focuses on the development and commercialization of new medicines to improve the lives of patients diagnosed with ras sarcoma (RAS)/ mitogen-activated pathway kinase (MAPK) pathway-driven cancers. Its product candidates include avutometinib and defactinib. Avutometinib is an oral RAF/MEK clamp that inhibits MEK1/2 kinase activities and induces inactive complexes of MEK with A-Raf proto-oncogene, potentially serine/threonine kinase (ARAF), B-Raf proto-oncogene serine/threonine kinase (BRAF) and C-raf proto-oncogene serine/threonine kinase, creating antitumor response through maximal RAS/MAPK pathway inhibition. Defactinib is an oral, selective inhibitor of FAK and proline-rich tyrosine kinase (PYK2), the two members of the focal adhesion kinase family of non-receptor protein tyrosine kinases. FAK and PYK2 integrate signals from integrin and growth factor receptors to regulate cell proliferation.
Show More

Events Timeline

(ET)
2026-05-07
16:10:00
Verastem Reports Q1 Revenue of $18.67M
select
2026-04-30 (ET)
2026-04-30
07:50:00
Verastem Oncology Launches Avmapki Fakzynja Co-Pack Treatment Campaign
select
2026-04-10 (ET)
2026-04-10
07:10:00
Verastem Oncology Presents Two-Year Follow-Up Data on AVMAPKI Combination Therapy
select

News

Newsfilter
1.0
05-12Newsfilter
Verastem Oncology Announces Investor Conference Schedule
  • Investor Conference Schedule: Verastem Oncology is set to participate in the HCW 4th Annual BioConnect Investor Conference on May 19, 2026, and the RBC Global Healthcare Conference on May 20, 2026, showcasing advancements in RAS/MAPK pathway-driven cancers, which is expected to attract investor interest and enhance company visibility.
  • Webcast Availability: The company will provide live webcasts of the presentations on its website under the 'Events & Presentations' section, with replays available for approximately 90 days post-event, ensuring that investors unable to attend live can still access critical information.
  • Product Market Positioning: Verastem Oncology focuses on developing and commercializing new medicines, particularly for patients with RAS/MAPK pathway-driven cancers, with existing products like AVMAPKI® and FAKZYNJA® CO-PACK in the market, indicating the company's potential in the biopharmaceutical sector.
  • R&D Pipeline Focus: The company's pipeline emphasizes novel small molecule drugs that inhibit critical signaling pathways promoting cancer cell survival and tumor growth, including RAF/MEK inhibition, FAK inhibition, and KRAS G12D inhibition, showcasing its innovative capabilities in cancer treatment.
Newsfilter
8.5
05-08Newsfilter
Launch of LGSOC Resource Guide to Support Patients
  • Resource Integration: The STAAR Low-Grade Serous Ovarian Cancer Foundation and Verastem Oncology have launched the LGSOC Resource Guide, designed to provide comprehensive educational materials and community resources for patients and caregivers dealing with this rare form of ovarian cancer, thereby addressing significant informational gaps.
  • Patient Engagement: The guide's release coincides with World Ovarian Cancer Day, emphasizing the critical role of patients in treatment decision-making, which helps them transition from feeling powerless to becoming active participants in their care, ultimately enhancing their quality of life and treatment confidence.
  • FDA Interaction: In 2023, STAAR held its first-ever Externally-led Patient-Focused Drug Development meeting with the FDA, advancing recognition of LGSOC as a distinct disease requiring dedicated treatment approaches, which facilitated the development of the first FDA-approved treatment for KRAS-mutated recurrent LGSOC.
  • Mental Health Focus: LGSOC patients face significant mental and physical health challenges, and the resource guide offers support information regarding emotional well-being and fertility, aiming to assist patients and their families in obtaining necessary support and information when confronting the disease.
seekingalpha
9.5
05-08seekingalpha
Verastem Q1 2026 Earnings Call Insights
  • Revenue Growth: Verastem achieved $18.7 million in net product revenue for Q1 2026, reflecting steady quarter-over-quarter growth and bringing total net revenue close to $50 million, indicating a stable market presence and potential for future expansion.
  • Leadership Change: The appointment of Dan Lyons as the new Chief Commercial Officer aims to enhance commercial execution, expected to drive effective transformations in marketing and sales strategies, thereby improving overall performance.
  • R&D Expenses: The company reported $38.2 million in R&D expenses for Q1, and despite facing seasonal challenges, it remains on track to achieve self-sustainability for the LGSOC franchise in the second half of 2026, demonstrating confidence in future profitability.
  • Clinical Advancements: Verastem anticipates initiating three registration-directed Phase II clinical trials for pancreatic cancer, non-small cell lung cancer, and colorectal cancer by mid-2026, further unlocking the market potential of VS-7375 and boosting investor confidence.
seekingalpha
9.5
05-07seekingalpha
Verastem Q1 2026 Earnings Beat Expectations
  • Earnings Highlights: Verastem's Q1 non-GAAP EPS of -$0.43 beats expectations by $0.04, although revenue of $18.67M misses by $2.72M, indicating improvements in cost management despite revenue challenges.
  • Clinical Trial Progress: Early data from the TARGET-D 101 trial is expected to be reported in 1H 2026, with an update on the trial's progress in 2H 2026, reflecting the company's ongoing commitment to R&D.
  • New Trial Initiation: The first patient in the TARGET-D 201, TARGET-D 202, and TARGET-D 203 clinical trials is expected to be initiated in mid-2026, showcasing the company's proactive approach in drug development.
  • Future Milestones: The RAMP 205 trial is set to report updates on safety and efficacy of the expansion cohort in Q2 2026, which is anticipated to provide critical data for metastatic pancreatic cancer treatment, further advancing the company's strategic development in oncology.
Newsfilter
8.5
04-30Newsfilter
Verastem Launches New Treatment for LGSOC
  • FDA Approval: Verastem Oncology's AVMAPKI®FAKZYNJA®CO-PACK received accelerated FDA approval on May 8, 2025, specifically designed for adult patients with KRAS-mutated recurrent low-grade serous ovarian cancer who have undergone prior systemic therapy, marking a significant advancement in treatment options.
  • Patient Support Initiative: The newly launched 'Reimagine Recurrent LGSOC' campaign aims to provide emotional resonance and practical information for both patients and healthcare professionals, helping patients better manage their condition and set treatment expectations, thereby enhancing their quality of life.
  • Market Demand Response: LGSOC is a rare cancer with a high recurrence rate, with approximately 30% of patients harboring KRAS mutations; Verastem's treatment not only fills a critical gap in this therapeutic area but also offers renewed hope for patients, potentially driving the company's growth in the biopharmaceutical market.
  • Clinical Trial Plans: Verastem is conducting the international Phase 3 confirmatory trial RAMP 301 to evaluate the combination of AVMAPKI and FAKZYNJA against standard chemotherapy, further validating its clinical benefits to ensure continued FDA approval.
Newsfilter
2.0
04-10Newsfilter
RAMP 201 Clinical Trial Data Released
  • Sustained Efficacy: In the RAMP 201 clinical trial, after a median follow-up of two years, 52% of patients with KRAS mutations and 30% of KRAS wild-type patients remained on therapy for over one year, indicating the durability and effectiveness of the treatment, potentially offering long-term options for patients.
  • Good Safety Profile: The combination therapy demonstrated no new safety signals during the two-year follow-up, with only a 12% discontinuation rate due to adverse events, suggesting that the treatment regimen is well-tolerated over extended periods, thereby enhancing patient confidence in the therapy.
  • Optimal Efficacy Analysis: Recent exposure-response analysis indicates that the best therapeutic effect of the combination therapy with avutometinib and defactinib is achieved at the approved doses, emphasizing the importance of dosing and scheduling, which provides guidance for clinical practice.
  • Clinical Significance: The findings reveal that approximately one-third of patients without KRAS mutations continued treatment after one year, highlighting the importance of this combination therapy in a patient population with limited treatment options, potentially paving the way for new therapeutic strategies in the future.
Wall Street analysts forecast VSTM stock price to rise
6 Analyst Rating
Wall Street analysts forecast VSTM stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
14.00
Averages
15.60
High
20.00
Current: 0.000
sliders
Low
14.00
Averages
15.60
High
20.00
Mizuho
Graig Suvannavejh
Outperform
to
Outperform
downgrade
$16 -> $14
AI Analysis
2026-05-14
Reason
Mizuho
Graig Suvannavejh
Price Target
$16 -> $14
AI Analysis
2026-05-14
downgrade
Outperform
to
Outperform
Reason
Mizuho analyst Graig Suvannavejh lowered the firm's price target on Verastem to $14 from $16 and keeps an Outperform rating on the shares. The firm updated the company's model post the Q1 report.
BTIG
Buy
maintain
$19 -> $18
2026-05-08
Reason
BTIG
Price Target
$19 -> $18
2026-05-08
maintain
Buy
Reason
BTIG lowered the firm's price target on Verastem to $18 from $19 and keeps a Buy rating on the shares after its Q1 results. The revamped commercial efforts should get the company back on track with long-term peak sales potential in LGSOC - Low-Grade Serous Ovarian Cancer - remaining intact, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for VSTM
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Valuation Metrics

The current forward P/E ratio for Verastem Inc (VSTM.O) is 0.00, compared to its 5-year average forward P/E of -5.05. For a more detailed relative valuation and DCF analysis to assess Verastem Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.05
Current PE
0.00
Overvalued PE
2.71
Undervalued PE
-12.81

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.20
Current EV/EBITDA
-0.64
Overvalued EV/EBITDA
0.39
Undervalued EV/EBITDA
-0.79

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
540.26
Current PS
1.97
Overvalued PS
2270.29
Undervalued PS
-1189.78

Financials

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Whales Holding VSTM

A
Armistice Capital LLC
Holding
VSTM
+6.99%
3M Return
R
RTW Investments, LP
Holding
VSTM
+0.39%
3M Return
D
Deep Track Capital, LP
Holding
VSTM
-5.73%
3M Return

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Frequently Asked Questions

What is Verastem Inc (VSTM) stock price today?

The current price of VSTM is 4.27 USD — it has increased 3.39

What is Verastem Inc (VSTM)'s business?

Verastem, Inc. is a late-stage development biopharmaceutical company, which focuses on the development and commercialization of new medicines to improve the lives of patients diagnosed with ras sarcoma (RAS)/ mitogen-activated pathway kinase (MAPK) pathway-driven cancers. Its product candidates include avutometinib and defactinib. Avutometinib is an oral RAF/MEK clamp that inhibits MEK1/2 kinase activities and induces inactive complexes of MEK with A-Raf proto-oncogene, potentially serine/threonine kinase (ARAF), B-Raf proto-oncogene serine/threonine kinase (BRAF) and C-raf proto-oncogene serine/threonine kinase, creating antitumor response through maximal RAS/MAPK pathway inhibition. Defactinib is an oral, selective inhibitor of FAK and proline-rich tyrosine kinase (PYK2), the two members of the focal adhesion kinase family of non-receptor protein tyrosine kinases. FAK and PYK2 integrate signals from integrin and growth factor receptors to regulate cell proliferation.

What is the price predicton of VSTM Stock?

Wall Street analysts forecast VSTM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for VSTM is15.60 USD with a low forecast of 14.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Verastem Inc (VSTM)'s revenue for the last quarter?

Verastem Inc revenue for the last quarter amounts to 18.67M USD, decreased

What is Verastem Inc (VSTM)'s earnings per share (EPS) for the last quarter?

Verastem Inc. EPS for the last quarter amounts to -0.37 USD, decreased -61.46

How many employees does Verastem Inc (VSTM). have?

Verastem Inc (VSTM) has 102 emplpoyees as of May 22 2026.

What is Verastem Inc (VSTM) market cap?

Today VSTM has the market capitalization of 362.92M USD.