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VSTM Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
5.380
Open
4.920
VWAP
5.20
Vol
3.58M
Mkt Cap
465.53M
Low
4.920
Amount
18.61M
EV/EBITDA(TTM)
--
Total Shares
87.84M
EV
307.64M
EV/OCF(TTM)
--
P/S(TTM)
10.87
Verastem, Inc. is a late-stage development biopharmaceutical company, which focuses on the development and commercialization of new medicines to improve the lives of patients diagnosed with ras sarcoma (RAS)/ mitogen-activated pathway kinase (MAPK) pathway-driven cancers. Its product candidates include avutometinib and defactinib. Avutometinib is an oral RAF/MEK clamp that inhibits MEK1/2 kinase activities and induces inactive complexes of MEK with A-Raf proto-oncogene, potentially serine/threonine kinase (ARAF), B-Raf proto-oncogene serine/threonine kinase (BRAF) and C-raf proto-oncogene serine/threonine kinase, creating antitumor response through maximal RAS/MAPK pathway inhibition. Defactinib is an oral, selective inhibitor of FAK and proline-rich tyrosine kinase (PYK2), the two members of the focal adhesion kinase family of non-receptor protein tyrosine kinases. FAK and PYK2 integrate signals from integrin and growth factor receptors to regulate cell proliferation.
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Events Timeline

(ET)
2026-03-04
16:10:00
Verastem Oncology Reports Q4 Revenue of $17.535M
select
2026-03-04
16:10:00
Expected Early Data Report from VS-7375-101 Trial in 1H 2026
select
2026-02-04 (ET)
2026-02-04
08:00:00
Verastem Oncology Launches First KRAS-Mutated Ovarian Cancer Treatment
select

News

Newsfilter
9.0
03-17Newsfilter
VS-7375 Demonstrates Strong Efficacy in Cancer Models
  • Significant Tumor Regression: In KRAS G12D pancreatic cancer models, the combination of VS-7375 with PRMT5 inhibitors demonstrated strong durable tumor regressions, indicating its potential as a new treatment option for patients with this cancer type.
  • Preclinical Research Findings: Compared to ON-only G12D inhibitors, VS-7375 showed deeper and more sustained tumor regression in pancreatic, lung, and colorectal cancer models, highlighting its advantages in clinical applications and the potential to change existing treatment protocols.
  • AACR Conference Presentation: Verastem Oncology will present multiple studies on VS-7375 at the 2026 American Association for Cancer Research Annual Meeting, enhancing its visibility in the oncology field and attracting investor interest.
  • FDA Fast Track Designation: The FDA granted Fast Track Designation to VS-7375 for treating KRAS G12D-mutated patients, indicating its therapeutic potential and possibly accelerating its market entry, thereby strengthening the company's competitive position in the biopharmaceutical market.
Newsfilter
9.0
03-17Newsfilter
Verastem Presents New Data from LGSOC Clinical Trial at SGO 2026
  • Clinical Trial Data Presentation: Verastem Oncology will present long-term data from the RAMP 201 clinical trial at the 2026 Annual Meeting on Women's Cancers, further validating the efficacy and safety of the combination therapy of avutometinib and defactinib for recurrent low-grade serous ovarian cancer, which is expected to enhance the clinical evidence base.
  • Exhibition Details: Verastem will have a booth (#608) at the meeting to showcase its approved therapies and ongoing cancer research, aiming to increase the company's visibility and influence in the oncology treatment space while attracting potential investors and partners.
  • Study Background: The RAMP 201 trial is a multicenter, randomized, open-label Phase 2 registration-directed trial evaluating the efficacy and safety of the combination of avutometinib and defactinib, with results providing critical insights for future treatment strategies, particularly in patients with KRAS mutations.
  • Patient Demographics: Low-grade serous ovarian cancer affects approximately 6,000 to 8,000 women in the U.S., with about 70% of patients exhibiting RAS pathway-associated mutations, highlighting the urgent need for developing new therapies targeting this specific cancer type to improve patient survival and treatment outcomes.
stocktwits
9.5
03-05stocktwits
Verastem Reports Q4 Earnings Beat, Stock Rises
  • Earnings Highlights: Verastem reported a Q4 adjusted loss of $0.48 per share, slightly above analysts' expectations of a $0.50 loss, while revenue of $17.5 million exceeded the consensus estimate of $16.84 million, indicating strong market performance post-drug launch.
  • Sales Growth: The Avmapki Fakzynja co-pack generated $17.5 million in Q4 revenue, with projections of $30.9 million for 2025, marking the company's first commercial success in the KRAS-mutated recurrent ovarian cancer market, enhancing its competitive position.
  • Clinical Trial Progress: The VS-7375 cancer drug cleared multiple dose levels in early trials without safety issues, with plans to pursue Phase 2 registration-directed studies across several cancer indications, showcasing its potential in oncology treatment.
  • Positive Investor Sentiment: Despite a 25% decline in VSTM stock year-to-date, shares rose nearly 3% in after-hours trading, reflecting investor optimism regarding the new therapy's early traction and upcoming clinical milestones.
seekingalpha
9.5
03-05seekingalpha
Verastem Q4 2025 Earnings Call Highlights
  • Financial Performance: Verastem reported $17.5 million in net product revenue for Q4 2025 and $30.9 million for the full year, indicating strong market acceptance and early commercial success, with expectations for the LGSOC franchise to become self-sustaining in H2 2026.
  • Clinical Progress: The company made advancements in the RAMP 205 trial, achieving a 57% overall response rate in KRAS mutant patients, suggesting that VS-7375 has significant potential in treating KRAS G12D-driven cancers, thereby reinforcing its strategic position in oncology.
  • Market Adoption: By February, nearly 300 prescribers had adopted CO-PACK, with over 75% of target institutions implementing the therapy, demonstrating effective outreach to healthcare providers and robust patient support strategies.
  • Future Outlook: Management reiterated a focus on maximizing CO-PACK adoption and plans to share updates on the RAMP 205 expansion cohort in Q2 2026, further driving clinical data generation and market penetration.
seekingalpha
9.5
03-04seekingalpha
Verastem Q4 Earnings Beat Expectations
  • Earnings Highlights: Verastem reported a Q4 GAAP EPS of -$0.50, beating expectations by $0.02, indicating a slight improvement in financial performance despite remaining in a loss position.
  • Revenue Growth: The company achieved Q4 revenue of $17.54 million, exceeding market expectations by $0.7 million, suggesting an increase in product acceptance in the market, which could lay the groundwork for future growth.
  • Clinical Developments: Verastem plans clinical updates in 2026, and despite setbacks with RAMP-203 targeting KRAS G12C NSCLC, the commitment to ongoing R&D may influence investor confidence positively.
  • Rating Adjustment: Following the RAMP-203 setback, Verastem's rating has been downgraded to “Buy,” which may impact short-term stock performance but could also present an entry opportunity for long-term investors.
seekingalpha
9.5
03-03seekingalpha
Verastem to Announce Q4 Earnings on March 4
  • Earnings Announcement: Verastem is set to release its Q4 2023 earnings on March 4 after market close, with a consensus EPS estimate of -$0.50, reflecting a 16.7% year-over-year improvement, indicating potential financial performance recovery.
  • Revenue Expectations: Analysts project Verastem's Q4 revenue to reach $16.84 million, suggesting a degree of stability and growth potential in the market despite ongoing challenges.
  • Historical Performance Review: Over the past two years, Verastem has beaten EPS estimates 63% of the time and revenue estimates 25% of the time, indicating a relatively reliable performance in financial forecasting that may influence investor confidence.
  • Clinical Trial Updates: Following setbacks with the RAMP-203 project, Verastem has downgraded its rating to Buy and plans to provide clinical updates in 2026, demonstrating the company's proactive approach to seeking future growth opportunities despite current challenges.
Wall Street analysts forecast VSTM stock price to rise
6 Analyst Rating
Wall Street analysts forecast VSTM stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
14.00
Averages
15.60
High
20.00
Current: 0.000
sliders
Low
14.00
Averages
15.60
High
20.00
Jefferies
Faisal Khurshid
initiated
$19 -> $15
AI Analysis
2026-03-30
New
Reason
Jefferies
Faisal Khurshid
Price Target
$19 -> $15
AI Analysis
2026-03-30
New
initiated
Reason
Jefferies analyst Faisal Khurshid assumed coverage of Verastem with a Buy rating and a price target of $15, down from $19. The firm sees \"a two-pillar story\" with drug CO-PACK providing \"a valuation floor,\" while G12D is \"the upside lever\" if the company can translate strong China data into \"a differentiated, combinable asset.\"
BTIG
Buy
initiated
$19
2026-03-11
Reason
BTIG
Price Target
$19
2026-03-11
initiated
Buy
Reason
BTIG assumed coverage of Verastem with a Buy rating and $19 price target. The firm views Verastem as an "undervalued oncology story." The shares are trading at an attractive entry point supported by its two main pipeline programs, the analyst tells investors in a research note. BTIG believes Verastem has commercial launch momentum in low-grade serous ovarian cancer.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for VSTM
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Valuation Metrics

The current forward P/E ratio for Verastem Inc (VSTM.O) is -3.46, compared to its 5-year average forward P/E of -5.15. For a more detailed relative valuation and DCF analysis to assess Verastem Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.15
Current PE
-3.46
Overvalued PE
2.51
Undervalued PE
-12.82

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.17
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.42
Undervalued EV/EBITDA
-0.77

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
663.71
Current PS
6.71
Overvalued PS
2487.62
Undervalued PS
-1160.20

Financials

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Whales Holding VSTM

V
Vivo Capital, LLC
Holding
VSTM
+14.23%
3M Return
T
Tang Capital Management, LLC
Holding
VSTM
+1.48%
3M Return
L
Logos Global Management, L.P.
Holding
VSTM
-3.05%
3M Return
R
RTW Investments, LP
Holding
VSTM
-3.28%
3M Return
D
Deep Track Capital, LP
Holding
VSTM
-5.60%
3M Return
A
Armistice Capital LLC
Holding
VSTM
-5.93%
3M Return

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Frequently Asked Questions

What is Verastem Inc (VSTM) stock price today?

The current price of VSTM is 5.3 USD — it has increased 9.28

What is Verastem Inc (VSTM)'s business?

Verastem, Inc. is a late-stage development biopharmaceutical company, which focuses on the development and commercialization of new medicines to improve the lives of patients diagnosed with ras sarcoma (RAS)/ mitogen-activated pathway kinase (MAPK) pathway-driven cancers. Its product candidates include avutometinib and defactinib. Avutometinib is an oral RAF/MEK clamp that inhibits MEK1/2 kinase activities and induces inactive complexes of MEK with A-Raf proto-oncogene, potentially serine/threonine kinase (ARAF), B-Raf proto-oncogene serine/threonine kinase (BRAF) and C-raf proto-oncogene serine/threonine kinase, creating antitumor response through maximal RAS/MAPK pathway inhibition. Defactinib is an oral, selective inhibitor of FAK and proline-rich tyrosine kinase (PYK2), the two members of the focal adhesion kinase family of non-receptor protein tyrosine kinases. FAK and PYK2 integrate signals from integrin and growth factor receptors to regulate cell proliferation.

What is the price predicton of VSTM Stock?

Wall Street analysts forecast VSTM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for VSTM is15.60 USD with a low forecast of 14.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Verastem Inc (VSTM)'s revenue for the last quarter?

Verastem Inc revenue for the last quarter amounts to 17.54M USD, decreased

What is Verastem Inc (VSTM)'s earnings per share (EPS) for the last quarter?

Verastem Inc. EPS for the last quarter amounts to -0.39 USD, decreased -70.45

How many employees does Verastem Inc (VSTM). have?

Verastem Inc (VSTM) has 102 emplpoyees as of April 01 2026.

What is Verastem Inc (VSTM) market cap?

Today VSTM has the market capitalization of 465.53M USD.