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RGLS

Regulus Therapeutics Inc
$
7.850
0.000(0.000%)
  • Overview
  • Forecast
  • Valuation
Line
Line
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Candle
Candle
1D
5D
1M
3M
6M
YTD
1Y
5Y
High
7.880
Open
7.830
VWAP
7.84
Vol
1.42M
Mkt Cap
543.15M
Low
7.810
Amount
11.10M
EV/EBITDA(TTM)
--
Total Shares
65.47M
EV
467.37M
EV/OCF(TTM)
--
P/S(TTM)
--
Regulus Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing drugs targeting microRNAs to treat diseases. The Company is leveraging its oligonucleotide drug discovery and development to develop a pipeline complemented by a rich intellectual property estate in the microRNA field. The Company’s lead product candidate includes RGLS8429. The Company is developing single-stranded oligonucleotides, which are chemically synthesized chains of nucleotides that are complementary to (thereby pairing with) the target microRNA. RGLS8429 is an anti-miR next-generation oligonucleotide targeting miR-17 for the treatment of autosomal dominant polycystic kidney disease (ADPKD). RGLS8429 maintains beneficial attributes, such as preferential kidney exposure and similar PK profile, miR-17 inhibition potency and duration of action in the kidney, equal potency in vitro and in vivo efficacy studies.
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Market Estimates

Earnings Estimates
Revenue
YoY Chg
EPS
YoYChg
FY2025Q3
FY2025Q2
FY2025Q1
--
--
-0.310
+47.62%
--
--
-0.310
+82.35%
--
--
-0.265
-8.62%
Estimates Revision
The market is revising No Change the revenue expectations for Regulus Therapeutics Inc. (RGLS) for FY2025, with the revenue forecasts being adjusted by % over the past three months. During the same period, the stock price has changed by 518.11%.
EPS Estimates for FY2025
Revise Downward
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-11.91%
In Past 3 Month
Stock Price
Go Up
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+518.11%
In Past 3 Month
5 Analyst Rating
up Image
62.42% Upside
Wall Street analysts forecast RGLS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for RGLS is 12.75 USD with a low forecast of 6.00 USD and a high forecast of 28.00  USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
5 Buy
0 Hold
0 Sell
Strong Buy
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62.42% Upside
Current: 7.850
sliders
Low
6.00
Averages
12.75
High
28.00
Wells Fargo
Yanan Zhu
Buy
to
Hold
Downgrades
$9
2025-05-01
New
Reason
Wells Fargo downgraded Regulus (RGLS) to Equal Weight from Overweight with a price target of $9, up from $6, after the company agreed to be acquired by Novartis (NVS) for $7 per share in cash and a $7 per share contingent value right.
Canaccord Genuity
Whitney Ijem
Strong Buy
to
Hold
Downgrades
$28 → $11
2025-04-30
Reason
Canaccord downgraded Regulus (RGLS) to Hold from Buy with a price target of $11, down from $28, after the company agreed to be acquired by Novartis (NVS) for $7 per share in cash and a $7 per share contingent value right.
Jones Trading
Catherine Novack
Strong Buy
to
Hold
Downgrades
$8 → $7
2025-04-30
Reason
JonesResearch analyst Catherine Novack downgraded Regulus (RGLS) to Hold from Buy with a price target of $7, down from $8, after the company agreed to be acquired by Novartis (NVS) for $7 per share in cash and a $7 per share contingent value right. The firm sees the valuation of the deal as "highly favorable" for Regulus, especially given financing overhang ahead of the Phase 3 trial.
Leerink Partners
Joseph Schwartz
Buy
to
Hold
Downgrades
$7
2025-04-30
Reason
Leerink downgraded Regulus (RGLS) to Market Perform from Outperform with a $7 price target after the company agreed to be acquired by Novartis (NVS) for $7 per share in cash and a $7 per share contingent value right.
Wells Fargo
Yanan Zhu
Hold
to
Buy
Upgrades
$3 → $6
2025-03-27
Reason
Wells Fargo upgraded Regulus to Overweight from Equal Weight with a price target of $6, up from $3.
Canaccord Genuity
Whitney Ijem
Strong Buy
Maintains
$28
2025-03-17
Reason

Valuation Metrics

The current forward P/E ratio for Regulus Therapeutics Inc (RGLS.O) is -5.98, compared to its 5-year average forward P/E of -1.74. For a more detailed relative valuation and DCF analysis to assess Regulus Therapeutics Inc 's fair value, click here.

Forward PE

StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.74
Current PE
-5.98
Overvalued PE
-0.69
Undervalued PE
-2.80

Forward EV/EBITDA

StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.08
Current EV/EBITDA
-6.93
Overvalued EV/EBITDA
0.71
Undervalued EV/EBITDA
-0.88

Forward PS

StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
598.34
Current PS
0.00
Overvalued PS
2251.68
Undervalued PS
-1055.00

Financials

Annual
Quarterly
FY2024Q4
N/A
Total Revenue
FY2024Q4
YoY :
+65.61%
-13.75M
Operating Profit
FY2024Q4
YoY :
+58.68%
-12.79M
Net Income after Tax
FY2024Q4
YoY :
-50.00%
-0.20
EPS - Diluted
FY2024Q4
YoY :
+91.17%
-11.85M
Free Cash Flow
FY2024Q4
N/A
Gross Profit Margin - %
FY2024Q4
N/A
FCF Margin - %
FY2024Q4
N/A
Net Margin - %

Trading Trends

Insider
Insiders areBuying! The selling amount has increased 930.87% over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
310.7K
USD
7
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
2
75.0K
USD
Months
6-9
0
0.0
USD
Months
0-12
1
7.3K
USD
Months
Hedge Fund
Hedge Funds areSelling! The selling amount has increased 5274.88% over the last quarter.
Sold
0-3
Months
0.0
Volume
0
3-6
Months
430.0K
Volume
1
6-9
Months
0.0
Volume
0
0-12
Months
8.0K
Volume
2
Bought
0-3
0
0.0
Volume
Months
3-6
0
0.0
Volume
Months
6-9
0
0.0
Volume
Months
0-12
0
0.0
Volume
Months
Congress Trading
Congress are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months

RGLS News & Events

Events Timeline

2025-05-01 (ET)
2025-05-01
08:45:01
Largest borrow rate increases among liquid names
select
2025-04-30 (ET)
2025-04-30
07:04:32
Regulus to be acquired by Novartis for $7.00 per share in cash
select
2025-03-27 (ET)
2025-03-27
07:04:17
Regulus' farabursen shows efficacy in Phase 1b kidney disease trial
select
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News

4.0
05-01Benzinga
This Parsons Analyst Is No Longer Bullish; Here Are Top 3 Downgrades For Thursday
7.0
05-01PRnewswire
SHAREHOLDER INVESTIGATION: Halper Sadeh LLC Investigates RGLS, KRON, SWTX on Behalf of Shareholders
8.5
05-01SeekingAlpha
Regulus CVR may be worth $3-$4 a share in Novartis deal - analyst
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FAQ

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The current price of RGLS is 7.85 USD — it has increased 0 % in the last trading day.

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