The chart below shows how KPTI performed 10 days before and after its earnings report, based on data from the past quarters. Typically, KPTI sees a +9.53% change in stock price 10 days leading up to the earnings, and a +0.42% change 10 days following the report. On the earnings day itself, the stock moves by -5.47%. This data can give you a slight idea of what to expect for the next quarter's release.
Positive
XPOVIO Revenue Increase: XPOVIO one product revenue was $29.5 million, up 5% compared to our results in the second quarter.
Quarterly Revenue Growth: We are very pleased with our third consecutive quarter-over-quarter growth of XPOVIO U.S. revenues amid a highly competitive market place and are well on track to deliver in the upper half of the guidance outlined at the start of the year.
Market Launch Potential: Our established commercial organization is well set up to potentially drive successful and rapid launches in myelofibrosis and endometrial cancer.
Strong Demand Growth: We achieved strong demand growth quarter over quarter in the community where XPOVIO tends to be used as a convenient or manageable option for patients as an earlier line of therapy or if the patients are unable to access a T-cell therapy.
Cost-Saving Initiatives Impact: We expect our 2025 operating expenses to be lower than 2024 as we recognize the full-year benefits of our ongoing cost-saving initiatives.
Negative
Quarterly Revenue Comparison: Total revenue for the third quarter of 2024 was $38.8 million, compared to $36 million for the third quarter of 2023, indicating a modest growth but not meeting expectations.
Revenue Decline Analysis: Net U.S. XPOVIO revenue for the third quarter of 2024 was $29.5 million, compared to $30.2 million for the third quarter of 2023, showing a decline in revenue.
Gross-to-Net Discount Increase: The gross-to-net discount for XPOVIO in the third quarter of 2024 was 31%, compared to 21% in the third quarter of 2023, indicating increased pricing pressure.
R&D Expense Increase: R&D expenses for the third quarter of 2024 were $36.1 million compared to $35.6 million for the third quarter of 2023, reflecting rising costs in clinical trials.
SG&A Expense Management: SG&A expenses for the third quarter of 2024 were $27.6 million, compared to $30.8 million for the third quarter of 2023, indicating ongoing cost management efforts but still higher than expected.
Karyopharm Therapeutics Inc. (KPTI) Q3 2024 Earnings Call Transcript
KPTI.O
3.6%