Werewolf Reports No Revenue in Fiscal Q2
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Aug 14 2025
0mins
Source: NASDAQ.COM
Financial Performance: Werewolf Therapeutics reported a GAAP EPS loss of $0.468 in Q2 2025, with no revenue generated, reflecting a decline from the previous year but aligning with expectations. Research and development expenses decreased by 14.4%, and the company maintains a cash runway into Q4 2026.
Clinical Development Focus: The company is advancing its lead assets, WTX-124 and WTX-330, through clinical trials while also innovating new products like WTX-1011 for prostate cancer. Key upcoming events include interim clinical data releases and regulatory discussions with the FDA planned for late 2025.
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Analyst Views on HOWL
Wall Street analysts forecast HOWL stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for HOWL is 4.00 USD with a low forecast of 1.00 USD and a high forecast of 7.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
4 Analyst Rating
2 Buy
2 Hold
0 Sell
Moderate Buy
Current: 0.714
Low
1.00
Averages
4.00
High
7.00
Current: 0.714
Low
1.00
Averages
4.00
High
7.00
About HOWL
Werewolf Therapeutics, Inc. is a biopharmaceutical company engaged in the development of therapeutics engineered to stimulate the body’s immune system for the treatment of cancer and other immune-mediated conditions. It is leveraging its PREDATOR platform to design conditionally activated molecules that stimulate both adaptive and innate immunity with the goal of addressing the limitations of conventional proinflammatory immune therapies. Its INDUKINE molecules are intended to remain inactive in peripheral tissue yet activate selectively in the tumor microenvironment. The Company’s advanced clinical-stage product candidates, WTX-124 and WTX-330, are systemically delivered, conditionally activated Interleukin-2 (IL-2) and IL-12 INDUKINE molecules for the treatment of solid tumors. It is advancing WTX-124 in multiple tumor types as a single agent and in combination with an immune checkpoint inhibitor. It is advancing WTX-712, WTX-518, and WTX-921 through preclinical development.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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Werewolf Reports 30% Response Rate for WTX-124 Monotherapy in Melanoma Patients
- Clinical Data Highlight: WTX-124 demonstrated a 30% overall response rate as a monotherapy in post-ICI advanced melanoma patients, indicating its potential as a best-in-class tolerability drug.
- Efficacy Validation: Initial data from WTX-330 further confirmed its antitumor activity and favorable tolerability, building on the first-in-human trial, showcasing its prospects in challenging tumor types.
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- Strategic Partnership Opportunities: Werewolf is seeking strategic partners to advance the WTX-124 and WTX-330 INDUKINE programs, leveraging its unique INDUCER T cell engager platform to enhance market competitiveness.
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