Oragenics Q2 2025 Shareholder Update
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Aug 11 2025
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Source: Newsfilter
Advancements in Neurotrauma Treatment: Oragenics, Inc. is progressing towards becoming the first company to receive FDA approval for a pharmacological treatment for concussion with its lead candidate ONP-002, utilizing proprietary intranasal delivery technology aimed at transforming neurotrauma care.
Strategic Growth and Market Potential: The company has secured key partnerships and funding to support clinical trials and manufacturing capabilities, positioning itself within a rapidly growing nasal drug delivery market projected to exceed $40 billion by 2030, while addressing the significant unmet medical need for effective concussion therapies.
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About OGEN
Oragenics, Inc. is a development-stage company. It is engaged in the research and development of nasal delivery pharmaceutical medications in neurology and fighting infectious diseases. It focuses on nasal delivery of pharmaceutical medications in neurology and fighting infectious diseases, including drug candidates for treating mild traumatic brain injury (mTBI or Concussion), and for treating Niemann Pick Disease Type C (NPC), and proprietary powder formulation and an intranasal delivery device. Its lead product, ONP-002, is a fully synthetic, non-naturally occurring neurosteroid, is lipophilic, and can cross the blood-brain barrier to rapidly reduce swelling, oxidative stress and inflammation while restoring proper blood flow through gene amplification. It is also focused on developing medical products that treat brain related illnesses and diseases (the Neurology Assets). Its other product candidate, ONP-001, is in its early stage and clinical trials.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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