Novo Nordisk vs. Eli Lilly: A Competitive Analysis
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1h ago
0mins
Source: Fool
- Market Competition Dynamics: Novo Nordisk's GLP-1 drugs Ozempic and Wegovy attracted significant investor interest upon launch, but as Eli Lilly's Mounjaro and Zepbound outperformed in the market, Novo Nordisk's stock price fell, highlighting market sensitivity to short-term performance.
- Significant Valuation Differences: Eli Lilly's price-to-earnings ratio stands at 50, while Novo Nordisk's is only 18; although Lilly's P/E is below its five-year average of 55, Novo Nordisk's valuation remains attractive relative to its historical levels, indicating long-term investment potential.
- Dividend Yield Comparison: Novo Nordisk offers a 2.8% dividend yield, significantly higher than Eli Lilly's 0.6%, making Novo Nordisk more appealing to investors seeking stable income, reflecting its robust cash flow generation capabilities.
- Core Business Stability: Despite facing competition in the GLP-1 space, Novo Nordisk's historical strength in insulin production and sales ensures ongoing customer demand, supporting the company's long-term growth and dividend payout capacity.
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Analyst Views on NVO
Wall Street analysts forecast NVO stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for NVO is 54.67 USD with a low forecast of 42.00 USD and a high forecast of 70.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
8 Analyst Rating
4 Buy
3 Hold
1 Sell
Moderate Buy
Current: 59.430
Low
42.00
Averages
54.67
High
70.00
Current: 59.430
Low
42.00
Averages
54.67
High
70.00
About NVO
Novo Nordisk A/S is a global healthcare company engaged in diabetes care. The Company is also engaged in the discovery, development, manufacturing and marketing of pharmaceutical products. The Company operates through two business segments: diabetes and obesity care, and biopharmaceuticals. The Company's diabetes and obesity care segment covers insulin, GLP-1, other protein-related products, such as glucagon, protein-related delivery systems and needles, and oral anti-diabetic drugs. The Company's biopharmaceuticals segment covers the therapy areas of hemophilia care, growth hormone therapy and hormone replacement therapy. The Company also offers Saxenda product to treat obesity. It offers a range of products, including NovoLog/NovoRapid; NovoLog Mix/NovoMix; Prandin/NovoNorm; NovoSeven; Norditropin, and Vagifem. As of December 31, 2016, it marketed its products in over 180 countries. Its regional structure consists of two commercial units: North America and International Operations.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Novo Nordisk Reveals REIMAGINE 2 Trial Results for CagriSema
- Clinical Trial Results: Novo Nordisk's REIMAGINE 2 trial results indicate that CagriSema achieved a HbA1c reduction of 1.91%-points over 68 weeks, significantly outperforming semaglutide's 1.76%-points, highlighting its potential in diabetes management.
- Weight Management Efficacy: The CagriSema 2.4 mg/2.4 mg group experienced a weight loss of 14.2% over 68 weeks compared to 10.2% for semaglutide, which not only enhances patient quality of life but also helps reduce the risk of diabetes-related complications.
- Weight Loss Success Rates: Among participants treated with CagriSema 2.4 mg/2.4 mg, 43% achieved ≥15% weight loss and 24% achieved ≥20%, demonstrating significant advantages in weight management that may attract more patients to this treatment option.
- Safety Profile Assessment: The trial results indicate that CagriSema has a favorable safety profile, with the most common adverse events being mild to moderate gastrointestinal issues that diminish over time, laying a solid foundation for its future market promotion.

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CagriSema Outperforms Wegovy in Weight Loss
- Weight Loss Comparison: CagriSema achieved a 14.2% weight loss over 68 weeks, significantly surpassing Wegovy's 10.2%, indicating CagriSema's greater potential in obesity treatment, which may attract more patients.
- Improved Glycemic Control: In the REIMAGINE 2 trial, CagriSema showed a reduction in HbA1C levels by 1.91 points compared to Wegovy's 1.76 points, highlighting its advantages in diabetes management and potentially enhancing Novo Nordisk's competitive position in the market.
- Innovative Administration: CagriSema is administered via subcutaneous injection once weekly, simplifying the medication process for patients, which may improve adherence and promote market acceptance of the drug.
- FDA Application Progress: Novo Nordisk submitted an application for CagriSema to the US FDA in December, and if approved, it will further solidify its leadership in obesity treatment and could lead to significant revenue growth.

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