Neurogene Announces Financial Results for Q3 2025 and Shares Recent Developments
Positive Clinical Data: Neurogene reported promising interim results from the NGN-401 Phase 1/2 gene therapy trial for Rett syndrome, showing durable gains in developmental milestones across eight pediatric participants.
Embolden Trial Initiation: The first participant has been dosed in the Embolden™ registrational trial for NGN-401, with full enrollment anticipated within three to six months.
Financial Position: Neurogene has a strong cash position of $265.4 million, expected to fund operations through the first quarter of 2028, despite a net loss of $21 million for the third quarter of 2025.
Innovative Gene Therapy Approach: NGN-401 utilizes Neurogene's proprietary EXACT™ transgene regulation technology to deliver the MECP2 gene, aiming to optimize therapeutic levels while minimizing toxicity, and has received multiple designations from regulatory agencies.
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Neurogene Announces Financial Results for Q3 2025 and Shares Recent Developments
Positive Clinical Data: Neurogene reported promising interim results from the NGN-401 Phase 1/2 gene therapy trial for Rett syndrome, showing durable gains in developmental milestones across eight pediatric participants.
Embolden Trial Initiation: The first participant has been dosed in the Embolden™ registrational trial for NGN-401, with full enrollment anticipated within three to six months.
Financial Position: Neurogene has a strong cash position of $265.4 million, expected to fund operations through the first quarter of 2028, despite a net loss of $21 million for the third quarter of 2025.
Innovative Gene Therapy Approach: NGN-401 utilizes Neurogene's proprietary EXACT™ transgene regulation technology to deliver the MECP2 gene, aiming to optimize therapeutic levels while minimizing toxicity, and has received multiple designations from regulatory agencies.
