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NGNE Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

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High
31.840
Open
30.470
VWAP
30.75
Vol
168.84K
Mkt Cap
480.65M
Low
29.630
Amount
5.19M
EV/EBITDA(TTM)
--
Total Shares
15.62M
EV
211.66M
EV/OCF(TTM)
--
P/S(TTM)
--
Neurogene Inc. is a clinical-stage biotechnology company. The Company, through its proprietary transgene regulation technology, Expression Attenuation via Construct Tuning (EXACT), is building a product portfolio of genetic medicines for rare neurological diseases with high unmet needs not otherwise addressable by conventional gene therapy. Its clinical-stage program, NGN-401, utilize the EXACT platform, which is in development for the treatment of Rett syndrome, a disease with a patient population that has a significant unmet need, and that ultimately progresses to substantial neurological and physical impairment and premature death. NGN-401 is being evaluated in female patients with Rett syndrome in a Phase 1/2 open-label, multi-center clinical trial that assesses the safety, tolerability, and efficacy of two doses of NGN-401 delivered using a one-time intracerebral ventricular (ICV) procedure. It is also developing NGN-101 for the treatment of CLN5 Batten disease.
Show More

Events Timeline

(ET)
2026-04-20
07:40:00
Neurogene Appoints Christy Shafer as Chief Commercial Officer
select
2026-03-24 (ET)
2026-03-24
16:20:00
Major Averages Close Lower as Oil Surges Above $90
select
2026-03-24
12:00:00
Dow Jones Up 0.31% to 46,350.65 Points
select
2026-03-24
07:40:00
Neurogene Completes Enrollment in Embolden Trial, Advances NGN-401
select

News

Newsfilter
8.5
04-28Newsfilter
Neurogene Advances Gene Therapy for CNS Diseases
  • ICV Delivery Advantage: Neurogene will present at the ASGCT meeting the biological rationale for ICV administration as a routine neurosurgical procedure, emphasizing its broad biodistribution in gene therapy for Rett syndrome, indicating significant implications for treating CNS diseases.
  • Clinical Safety Data: Research indicates that the clinical safety of ICV administration is primarily driven by the product itself rather than the delivery route, with ICV showing a well-tolerated profile, supporting its further clinical application.
  • Clinical Trial Results: In the ongoing Phase 1/2 trial, NGN-401 at a 1E15 vg dose demonstrated durable developmental milestone gains across multiple domains in participants, highlighting the therapy's potential in treating Rett syndrome.
  • Regulatory Recognition: NGN-401 has received multiple designations from the FDA, including Breakthrough Therapy and Regenerative Medicine Advanced Therapy, showcasing its market potential as a best-in-class gene therapy and enhancing investor and market confidence.
seekingalpha
9.5
03-24seekingalpha
Neurogene Reports FY GAAP EPS of -$4.24, Exceeding Expectations
  • Earnings Report Surprise: Neurogene's FY GAAP EPS of -$4.24 surpassed market expectations by $0.04, indicating some resilience in financial management despite the ongoing losses.
  • Strong Cash Reserves: As of December 31, 2025, Neurogene reported cash, cash equivalents, and short-term investments totaling $269 million, which is expected to fund operations through the first quarter of 2028, ensuring liquidity in the near term.
  • FDA Designation Impact: The stock surged following Neurogene's FDA designation for its Rett syndrome gene therapy, although the market remains cautious about its long-term prospects, reflecting a balance between investor optimism and risk.
  • Market Analysis Focus: Seeking Alpha's Quant Rating on Neurogene remains cautious, highlighting that while financial data shows short-term improvement, long-term profitability needs further observation, urging investors to stay vigilant against potential volatility.
Newsfilter
9.5
03-24Newsfilter
Neurogene Reports 2025 Financial Results and Updates
  • Trial Progress: Neurogene has successfully enrolled 100% of participants in the Embolden™ registrational trial, with over 50% already dosed, and is on track to complete dosing by the second quarter of 2026, laying a solid foundation for the potential launch of NGN-401.
  • Efficacy and Safety Recognition: NGN-401 has demonstrated good tolerability at the 1E15 vg dose in the Phase 1/2 trial, with no cases of hemophagocytic lymphohistiocytosis (HLH), and has received FDA Breakthrough Therapy designation, indicating strong market potential.
  • Strong Financial Position: As of December 31, 2025, Neurogene reported cash and short-term investments totaling $269 million, which is expected to fund operations through the first quarter of 2028, ensuring ongoing support for R&D and market initiatives.
  • Future Milestones Planned: The company plans to initiate the Process Performance Qualification (PPQ) campaign in mid-2026 and present updated safety and efficacy data for both pediatric and adolescent/adult cohorts in mid-2026, further enhancing market confidence.
moomoo
9.0
03-24moomoo
NEUROGENE INC - FULL ENROLLMENT ACHIEVED AND OVER 50% DOSING IN EMBOLDEN TRIAL; EXPECTED TO FINISH DOSING BY Q2 2026
  • Enrollment Statistics: Neurogene has achieved 100% enrollment in its clinical trial.

  • Dosing Progress: More than 50% of participants have received their doses in the trial.

  • Trial Completion Timeline: The trial is expected to be completed by Q2 2026.

  • Focus on Treatment: The trial is part of Neurogene's efforts to advance treatments in the field.

moomoo
9.5
03-24moomoo
NEUROGENE REPORTS FY NET INCOME OF -$90.351 MILLION
  • Company Overview: Neurogene is a biotechnology company focused on developing gene therapies for rare neurological diseases.

  • Recent Financial Update: The company reported a net income of USD 90.351 million, indicating significant financial activity or investment.

moomoo
9.5
03-24moomoo
NEUROGENE REPORTS FY OPERATING LOSS OF USD 103.328 MILLION
  • Financial Overview: Neurogene reported an operating income of USD 103.328 million.
  • Company Performance: The financial results indicate a significant milestone for Neurogene in its operational activities.
Wall Street analysts forecast NGNE stock price to rise
5 Analyst Rating
Wall Street analysts forecast NGNE stock price to rise
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
46.00
Averages
58.00
High
70.00
Current: 0.000
sliders
Low
46.00
Averages
58.00
High
70.00
Guggenheim
Buy
initiated
$69
AI Analysis
2026-04-28
Reason
Guggenheim
Price Target
$69
AI Analysis
2026-04-28
initiated
Buy
Reason
Guggenheim initiated coverage of Neurogene with a Buy rating and $69 price target.
Canaccord
Buy
downgrade
$200 -> $180
2026-04-06
Reason
Canaccord
Price Target
$200 -> $180
2026-04-06
downgrade
Buy
Reason
Canaccord lowered the firm's price target on Neurogene to $180 from $200 and keeps a Buy rating on the shares. The firm updated its model for 4Q25 results, company commentary and incorporated their newly launched Rett disease model on the back of our recent KOL call
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Valuation Metrics

The current forward P/E ratio for Neurogene Inc (NGNE.O) is 0.00, compared to its 5-year average forward P/E of -6.03. For a more detailed relative valuation and DCF analysis to assess Neurogene Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-6.03
Current PE
0.00
Overvalued PE
-3.43
Undervalued PE
-8.64

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
114.42
Current PS
0.00
Overvalued PS
430.16
Undervalued PS
-201.32

Financials

AI Analysis
Annual
Quarterly

Whales Holding NGNE

E
EcoR1 Capital, LLC
Holding
NGNE
+13.84%
3M Return
L
Logos Global Management, L.P.
Holding
NGNE
+4.10%
3M Return

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Frequently Asked Questions

What is Neurogene Inc (NGNE) stock price today?

The current price of NGNE is 30.78 USD — it has decreased -1.54

What is Neurogene Inc (NGNE)'s business?

Neurogene Inc. is a clinical-stage biotechnology company. The Company, through its proprietary transgene regulation technology, Expression Attenuation via Construct Tuning (EXACT), is building a product portfolio of genetic medicines for rare neurological diseases with high unmet needs not otherwise addressable by conventional gene therapy. Its clinical-stage program, NGN-401, utilize the EXACT platform, which is in development for the treatment of Rett syndrome, a disease with a patient population that has a significant unmet need, and that ultimately progresses to substantial neurological and physical impairment and premature death. NGN-401 is being evaluated in female patients with Rett syndrome in a Phase 1/2 open-label, multi-center clinical trial that assesses the safety, tolerability, and efficacy of two doses of NGN-401 delivered using a one-time intracerebral ventricular (ICV) procedure. It is also developing NGN-101 for the treatment of CLN5 Batten disease.

What is the price predicton of NGNE Stock?

Wall Street analysts forecast NGNE stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for NGNE is58.00 USD with a low forecast of 46.00 USD and a high forecast of 70.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Neurogene Inc (NGNE)'s revenue for the last quarter?

Neurogene Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Neurogene Inc (NGNE)'s earnings per share (EPS) for the last quarter?

Neurogene Inc. EPS for the last quarter amounts to -1.12 USD, increased 12.00

How many employees does Neurogene Inc (NGNE). have?

Neurogene Inc (NGNE) has 131 emplpoyees as of May 11 2026.

What is Neurogene Inc (NGNE) market cap?

Today NGNE has the market capitalization of 480.65M USD.