Molecular Partners Presents Initial MP0533 Trial Data, 8 Patients Achieve Response
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 07 2025
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Source: Globenewswire
- Clinical Trial Progress: As of September 1, 2025, 54 patients have been treated with MP0533, with 8 achieving a response, including 5 reaching composite complete responses, indicating the drug's potential in acute myeloid leukemia (AML) patients.
- Dosing Optimization Effects: The accelerated dosing and higher frequency of MP0533 have proven feasible, with preliminary data showing significantly improved serum exposure in treatment cycle 1, potentially offering better treatment options for patients.
- Patient Selection Advantage: Among the 8 responders, 6 had baseline bone marrow blast counts below 20%, suggesting that patients with lower disease burdens are more likely to benefit from MP0533, supporting further clinical investigation.
- Future Research Directions: Molecular Partners is actively engaging with potential partners to explore the application of MP0533 in front-line AML treatment, demonstrating the company's confidence in the drug's future development.
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Analyst Views on MOLN
Wall Street analysts forecast MOLN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MOLN is 10.00 USD with a low forecast of 8.00 USD and a high forecast of 12.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
2 Analyst Rating
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 4.150
Low
8.00
Averages
10.00
High
12.00
Current: 4.150
Low
8.00
Averages
10.00
High
12.00
About MOLN
Molecular Partners AG is a Switzerland-based clinical-stage biotech company developing DARPin (Designed Ankyrin Repeat Proteins) a new class of custom-built protein therapeutics based on natural binding proteins that open a new dimension of multi-functionality and multi-target specificity in drug design. The Company has formed partnerships with leading pharmaceutical companies to advance DARPin therapeutics , and has compounds in various stages of clinical and preclinical development across multiple therapeutic areas.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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Molecular Partners Initiates MP0712 Clinical Trial, First Patient Dosing Expected Q1 2026
- Clinical Trial Launch: Molecular Partners has initiated a Phase 1/2a clinical trial for MP0712 in the US, with first patient dosing expected in Q1 2026, aiming to assess safety and determine the recommended dose, thereby enhancing the company's leadership in targeted radiotherapy.
- Strong Cash Position: As of December 31, 2025, the company reported cash and cash equivalents of CHF 93.1 million, which is projected to fund operating expenses and capital expenditures until 2028, ensuring the company's capacity for R&D and market expansion in the coming years.
- New Drug Development Progress: The Phase 2 trial for MP0317 is now open, targeting 75 patients to evaluate the clinical benefits of its combination with standard care, thereby strengthening the company's competitive position in cholangiocarcinoma treatment.
- Multi-Target Therapy: The Phase 1/2a trial for MP0533 is ongoing, with preliminary data indicating good tolerability and antitumor activity in acute myeloid leukemia patients, with an update on the clinical development path expected in H1 2026, further solidifying the company's product pipeline.
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