Fractyl Health Appoints Lara Smith Weber as CFO Effective January 12, 2026
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 06 2026
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Source: NASDAQ.COM
- Executive Change: Fractyl Health announced the appointment of Lara Smith Weber as Chief Financial Officer, effective January 12, 2026, succeeding Lisa Davidson who stepped down on December 31, 2025, aiming to provide financial support during a critical development phase.
- Financial Background: Most recently, Weber served as CFO of Inari, where she successfully completed multiple financings and strengthened the company's capital structure, establishing financial systems and processes that will lay the groundwork for Fractyl's commercial execution and scaling efforts.
- CEO Commentary: CEO Harith Rajagopalan noted that Weber's experience in building financial and operational discipline in growth-stage healthcare companies makes her well-suited to support Fractyl as it navigates pivotal development stages.
- Market Reaction: Fractyl's stock closed at $2.06, down 8.44% on Nasdaq, reflecting a negative market response to the executive change, which may impact investor confidence.
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Analyst Views on GUTS
Wall Street analysts forecast GUTS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for GUTS is 7.25 USD with a low forecast of 5.00 USD and a high forecast of 8.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
4 Analyst Rating
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 1.830
Low
5.00
Averages
7.25
High
8.00
Current: 1.830
Low
5.00
Averages
7.25
High
8.00
About GUTS
Fractyl Health, Inc. is a metabolic therapeutics company. The Company is focused on developing new approaches to the treatment of metabolic diseases, including obesity and type 2 diabetes (T2D). The Company’s lead product candidate, Revita, is designed to remodel the duodenal lining via hydrothermal ablation (i.e. duodenal mucosal resurfacing) to reverse damage to intestinal nutrient sensing and signaling mechanisms caused by chronic high-fat and high-sugar diets that are a root cause of metabolic disease. The Revita clinical program is focused on patients living with obesity who want to maintain their weight loss after GLP-1 drug discontinuation. The Company’s Rejuva platform focuses on developing adeno-associated virus (AAV)-based, locally delivered gene therapies for the treatment of obesity and T2D. The Rejuva platform leverages advanced delivery systems and proprietary screening methods to identify and develop metabolically active gene therapy candidates targeting the pancreas.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Fractyl Health Shares Plunge 64% After Disappointing Data Release
- Efficacy Data Release: Fractyl Health reported six-month data on its Revita endoscopic procedure, revealing a 4.5% weight regain in Revita patients compared to 7.5% in the placebo group, indicating the therapy's effectiveness in maintaining weight loss is below expectations.
- Exploratory Analysis Results: Among patients who achieved above-average weight loss on GLP-1 drugs, those receiving Revita experienced a 4.2% weight regain versus 13.3% in the placebo group, suggesting potential advantages for Revita in specific patient populations, although overall efficacy remains to be validated.
- Study Design Limitations: Fractyl noted that the midpoint cohort was not designed to be sufficiently powered for efficacy analysis, which may undermine the reliability of the results and lead to decreased market confidence in the company's future prospects.
- Future Outlook: The company plans to release one-year midpoint cohort results in Q3 and aims for an application submission in H2, presenting an opportunity to potentially restore market confidence despite the current disappointing data.
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DJS Law Group Investigates Claims for Fractyl Health Investors
- Investigation Background: DJS Law Group is investigating Fractyl Health (NASDAQ: GUTS) for potential violations of securities laws, focusing on whether the company issued misleading statements or failed to disclose material information to investors.
- FDA Feedback Request: On January 29, 2026, Fractyl Health requested FDA feedback on potentially reclassifying Revita under the De Novo pathway instead of seeking Premarket Approval (PMA), drawing significant market attention.
- Stock Price Plunge: Following this news, shares of Fractyl Health fell by 67.48% in intraday trading on the same day, indicating substantial investor concern regarding the company's future prospects.
- Commitment to Legal Services: DJS Law Group is dedicated to enhancing investor returns through balanced counseling and aggressive advocacy, specializing in securities class actions and corporate governance litigation.
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