FibroBiologics Files IND for CYPS317 Clinical Trials Targeting Psoriasis
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 31 2025
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Source: Newsfilter
- Major Advancement: FibroBiologics has filed an IND application for CYPS317, a Phase 1/2 clinical trial, marking a significant step forward in its chronic inflammatory disease pipeline and expected to drive innovation in skin disease treatment.
- Efficacy Validation: Preclinical studies indicate that a single dose of CYPS317 matches the efficacy of multiple doses of anti-IL-23 monoclonal antibodies, significantly reducing disease recurrence, highlighting its potential in psoriasis treatment.
- Market Demand: Psoriasis affects over 8 million adults in the U.S., and despite advances in biologic treatments, unmet needs persist; CYPS317 aims to provide more durable efficacy and favorable safety profiles.
- Strategic Goals: FibroBiologics aims to achieve IND clearance for all four product candidates by 2026, with this filing representing a pivotal transition to clinical development, underscoring the company's commitment to innovation and clinical rigor.
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Analyst Views on FBLG
Wall Street analysts forecast FBLG stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for FBLG is 3.25 USD with a low forecast of 1.50 USD and a high forecast of 5.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
2 Analyst Rating
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.341
Low
1.50
Averages
3.25
High
5.00
Current: 0.341
Low
1.50
Averages
3.25
High
5.00
About FBLG
FibroBiologics, Inc. is a clinical-stage biotechnology company. The Company is focused on developing and commercializing fibroblast-based therapies for patients suffering from chronic diseases with significant unmet medical needs, including wound healing, multiple sclerosis, degenerative disc disease, psoriasis and certain cancers, and potential human longevity applications including thymic involution reversal. Its product candidates include CybroCell, CYMS101 and CYWC628. CybroCell is an allogeneic fibroblast cell-based therapy for degenerative disc disease. This technology is being designed as an alternative method for repairing the cartilage of the intervertebral disc (or any other articular cartilage). It is developing CYMS101 as an allogeneic fibroblast cell-based therapy to treat multiple sclerosis (MS) and has completed the Phase I study. It is developing CYWC628 as an allogeneic fibroblast cell-based therapy for wound healing. Its CYPS317 is used for the treatment of Psoriasis.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
FibroBiologics CEO Pete O'Heeron to Present at DealFlow Discovery Conference on January 29, 2026
- Conference Presentation: FibroBiologics' Founder and CEO Pete O'Heeron will present at the DealFlow Discovery Conference on January 29, 2026, showcasing the company's latest advancements in chronic disease therapeutics.
- Investor Meetings: Throughout the event, FibroBiologics will offer one-on-one investor meetings aimed at attracting potential investors and demonstrating its innovative capabilities in cell therapy and tissue regeneration.
- Patent Portfolio: The company holds over 270 issued and pending patents across various clinical pathways, including wound healing, cancer, and human longevity, highlighting its strong R&D capabilities in the biotechnology sector.
- Industry Outlook: As a clinical-stage biotechnology firm, FibroBiologics is driving the next generation of medical advancements in cell therapy, aiming to provide potential cures for chronic diseases, which presents significant market potential and strategic importance.
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