EyePoint Completes Enrollment of Pivotal Phase 3 Trials for DURAVYU™ in Wet Age-Related Macular Degeneration
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jul 29 2025
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Source: Newsfilter
Enrollment and Trial Progress: EyePoint Pharmaceuticals has successfully completed enrollment for its Phase 3 pivotal trials, LUGANO and LUCIA, evaluating DURAVYU for wet age-related macular degeneration (AMD), with over 800 patients enrolled across both trials, marking one of the fastest enrollment rates in this field.
Safety and Efficacy Data: Interim analysis confirmed a favorable safety profile for DURAVYU, consistent with previous trials, while topline data from the trials is expected to be released in mid-2026, aiming to provide innovative treatment options that reduce the burden of frequent injections for patients.
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Analyst Views on EYPT
Wall Street analysts forecast EYPT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for EYPT is 31.50 USD with a low forecast of 20.00 USD and a high forecast of 43.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
6 Analyst Rating
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 15.040
Low
20.00
Averages
31.50
High
43.00
Current: 15.040
Low
20.00
Averages
31.50
High
43.00
About EYPT
EyePoint, Inc., formerly EyePoint Pharmaceuticals, Inc., is a clinical-stage biopharmaceutical company. The Company is focused on developing and commercializing therapeutics to improve the lives of patients with serious retinal diseases. The Company’s lead product candidate, DURAVYU, is an investigational-sustained delivery treatment for serious retinal diseases combining vorolanib, a selective and patent-protected tyrosine kinase inhibitor, with bioerodible Durasert E technology. Vorolanib features a novel multi-mechanism of action as it targets both vascular endothelial growth factor (VEGF)-mediated vascular permeability and IL-6 mediated inflammation through inhibition of all VEGF receptors and pro-inflammatory IL-6/JAK1 signaling. DURAVYU is in Phase III pivotal trials for wet age-related macular degeneration. DURAVYU is also being advanced for the treatment of diabetic macular edema (DME) with the first patient dosing in Phase III trials.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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