Serina Therapeutics Appoints Joshua Thomas as VP of Chemistry to Advance POZ Platform
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 11 2025
0mins
Should l Buy SER?
Source: Globenewswire
- Leadership Expansion: Serina Therapeutics has appointed Dr. Joshua Thomas as Vice President of Chemistry, tasked with optimizing POZ platform-based drug candidates, aiming to enhance efficiency from discovery to development and strengthen the company's competitive edge in neurological disease treatments.
- Experienced Leadership: Dr. Thomas brings 13 years of scientific leadership experience from Mersana Therapeutics, where he contributed to the development of antibody-drug conjugate (ADC) technologies, which is expected to introduce innovative ideas and technical support to Serina's drug development efforts.
- Strategic Platform Advancement: His appointment will drive Serina's expansion of the POZ platform into two new therapeutic modalities, further enhancing market opportunities in small molecule drugs to meet the growing patient demand.
- Deepening Scientific Collaboration: Over the past two years, Dr. Thomas has positively influenced the evolution of the POZ chemistry platform while working closely with Serina as a consultant, and he will continue to promote the integration of scientific research with clinical applications moving forward.
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Analyst Views on SER
Wall Street analysts forecast SER stock price to rise
1 Analyst Rating
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 1.700
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11.00
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Current: 1.700
Low
11.00
Averages
11.00
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11.00
About SER
Serina Therapeutics Inc. is a clinical-stage biotechnology company developing a pipeline of wholly owned drug product candidates to treat neurological diseases and other indications. The Company's POZ Platform provides the potential to improve the integrated efficacy and safety profile of multiple modalities including small molecules, RNA-based therapeutics and antibody-based drug conjugates (ADCs). Its proprietary POZ technology is based on a synthetic, water soluble, low viscosity polymer called poly(2-oxazoline). Its POZ technology is engineered to provide greater control in drug loading and more precision in the rate of release of attached drugs delivered via subcutaneous injection. SER-252 is the Company’s lead candidate for advanced Parkinson’s disease. SER-252 is an investigational apomorphine therapy developed with its POZ platform and designed to provide continuous dopaminergic stimulation.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Technology Platform Overview: Serina's POZ Platform™ aims to optimize the efficacy and safety of drug candidates across various modalities, including small molecules, RNA therapeutics, and antibody-drug conjugates, showcasing its potential in treating neurological diseases.
- Industry Impact Analysis: The event will provide attendees with the opportunity to directly question management, reflecting investor concerns regarding FDA policy changes that could influence investment decisions in the biotechnology sector.
- Company Background Information: Serina Therapeutics is a clinical-stage biotechnology company headquartered in Huntsville, Alabama, focused on developing drug candidates for neurological diseases, demonstrating its innovative capabilities in the life sciences field.
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- CEO Presentation Event: Steven Ledger, CEO of Serina Therapeutics, will present at Tribe Public's webinar on February 4, 2026, discussing FDA initiatives that may impact drug development timelines and review processes, potentially altering investor expectations.
- Technology Platform Overview: Serina's POZ Platform™ aims to optimize the efficacy and safety of drug candidates across various modalities, including small molecules, RNA therapeutics, and antibody-drug conjugates, showcasing its potential in treating neurological diseases.
- Industry Impact Analysis: The event will provide attendees with the opportunity to directly question management, reflecting investor concerns regarding FDA policy changes that could influence investment decisions in the biotechnology sector.
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- Disappointing Delivery Numbers: Xpeng Inc reported delivering 20,011 vehicles in January 2026, a figure that, while substantial, fell short of market expectations, leading to a decline in investor confidence.
- Stock Price Reaction: Following the disappointing delivery results, Xpeng's stock dropped 5.6% in pre-market trading to $16.97, reflecting concerns about the company's future performance among investors.
- Overall Market Trend: U.S. stock futures were lower, with Dow futures falling around 100 points, indicating a cautious market sentiment that could further impact investor attitudes towards Xpeng.
- Industry Impact: The delivery figures from Xpeng may negatively affect overall confidence in the electric vehicle market, especially in an increasingly competitive landscape, prompting investors to reassess their strategies.
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- Significant Revenue Growth: DarkIris Inc reported a year-over-year revenue increase of 27.3% for FY25, reaching $10.08 million compared to $7.92 million in FY24, indicating strong market performance and growth potential.
- Stock Price Surge: Following the positive earnings report, DarkIris shares jumped 104.2% in pre-market trading to $0.68, reflecting investor optimism about the company's future prospects.
- Positive Market Reaction: The release of this earnings report has significantly increased market attention on DarkIris, enhancing investor confidence in its continued growth and potentially attracting more capital inflow.
- Optimistic Industry Outlook: The robust performance of DarkIris not only strengthens its market position but may also provide more opportunities for future financing and expansion plans, further solidifying its competitive edge in the industry.
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Serina Therapeutics Receives FDA Clearance for IND Application
- FDA IND Clearance: Serina Therapeutics announced that its IND application for SER-252 has been cleared by the FDA, allowing the company to proceed with preparations for a planned Phase 1b registrational study, which is expected to significantly advance treatment options for Parkinson's disease patients.
- Stock Surge: Following the FDA clearance announcement, Serina's shares surged over 70% in pre-market trading, reflecting strong market optimism for the therapy, particularly after experiencing a setback in November 2025 when the FDA placed a clinical hold on its trials.
- Trial Design Support: The FDA had previously provided written feedback supporting Serina's proposed registrational trial design under the 505(b)(2) NDA pathway, indicating a clear path forward for the therapy to address significant unmet medical needs.
- Market Sentiment Shift: Following the announcement, investor sentiment on Stocktwits shifted from 'bearish' to 'extremely bullish', accompanied by a surge in message volume, indicating strong market interest and potential investment opportunities for SER-252.
See More
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- Strong Financial Results: Meta reported fourth-quarter revenue of $59.89 billion, exceeding analyst expectations of $58.30 billion, indicating robust performance in the recovering advertising market, which is likely to drive further stock price increases.
- Earnings Growth: The company posted adjusted earnings of $8.88 per share, surpassing the forecast of $8.16 per share, reflecting significant improvements in cost control and operational efficiency, thereby boosting investor confidence.
- Stock Price Surge: Following the earnings report, Meta's shares jumped 8.2% in pre-market trading to $723.70, indicating a positive market sentiment towards the company's growth prospects, which may attract more investor interest.
- Optimistic Sales Guidance: Meta's first-quarter sales guidance exceeded market expectations, further solidifying its leadership position in the digital advertising space and suggesting continued benefits from the recovery in advertising spending.
See More
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- Earnings Impact: Meta's strong sales forecast and $100 billion AI investment plan drove its stock up in after-hours trading, while Microsoft fell due to slowing cloud growth and soft margin guidance, indicating a divergence in market sentiment towards tech stocks.
- Commodity Market Fluctuations: Gold prices nearing $5600 and silver surpassing $120 reflect investors' demand for safe-haven assets amid economic uncertainty, simultaneously boosting trading volumes in related ETFs like GLD and SLV.
- Market Sentiment: Despite Nasdaq and S&P 500 futures rising by 0.4% and 0.3% respectively, retail sentiment towards SPY and QQQ remains extremely bearish, suggesting ongoing investor concerns about market outlook.
- Upcoming Earnings Reports: Investors are keenly awaiting Apple's earnings report, particularly for insights on iPhone demand and AI roadmap updates, while Western Digital and SanDisk are also set to report today, potentially impacting the data storage sector.
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