Regeneron Pharmaceuticals (REGN): Analyzing Valuation Following Recent Share Price Surge
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Nov 26 2025
0mins
Should l Buy REGN?
Source: Yahoo Finance
Regeneron Pharmaceuticals Performance: Regeneron shares have gained 36% over the past month, reflecting strong revenue and net income growth, with a total shareholder return of 54% over five years.
Valuation Insights: Analysts consider Regeneron overvalued at a fair value of $753.17 compared to its current market price of $787.32, raising questions about future growth potential and investment opportunities.
Product Growth and Risks: The successful adoption of EYLEA HD and potential regulatory approvals could support revenue growth, but ongoing manufacturing delays and competition pose risks to these optimistic forecasts.
Market Positioning: Regeneron's price-to-earnings ratio of 17.6x is lower than industry averages, suggesting either cautious market pricing or potential hidden investment opportunities.
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Analyst Views on REGN
Wall Street analysts forecast REGN stock price to rise
22 Analyst Rating
16 Buy
6 Hold
0 Sell
Moderate Buy
Current: 783.650
Low
637.00
Averages
808.50
High
1057
Current: 783.650
Low
637.00
Averages
808.50
High
1057
About REGN
Regeneron Pharmaceuticals, Inc. is a fully integrated biotechnology company. The Company invents, develops, manufactures, and commercializes medicines for people with serious diseases. Its products and product candidates in development are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurological diseases, hematologic conditions, infectious diseases, and rare diseases. The Company is accelerating drug development using its proprietary technologies, such as VelociSuite, which produces optimized fully human antibodies and new classes of bispecific antibodies. VelociSuite consists of VelocImmune, VelociGene, VelociMouse, VelociMab, Veloci-Bi, VelociT, VelociHum, and other related technologies. Its marketed products include EYLEA (aflibercept); Dupixent (dupilumab); Libtayo (cemiplimab); Ordspono (odronextamab); Kevzara (sarilumab); Itepekimab; Linvoseltamab, and others.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Pipeline Advancement: The company continues to advance its in vivo liver editing programs, with CTX310 in Phase 1b trials for lipid disorders and CTX321 progressing through enabling studies, with updates expected in the second half of 2026.
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- Leadership Transition: Sanofi announced that CEO Paul Hudson will depart on February 17, with Belén Garijo succeeding him, reflecting ongoing challenges in the company's drug pipeline and market performance, which may impact investor confidence.
- Sales Performance Fluctuations: While Sanofi's top drug Dupixent saw a 32.2% sales increase in Q4 2025, totaling €4.2 billion, vaccine sales declined by 2.5% to €2 billion, highlighting vulnerabilities in its product portfolio.
- Weak Stock Performance: Sanofi shares fell 0.68% in premarket trading to $46.71, trading 1.1% below the 20-day and 4% below the 100-day simple moving averages, indicating a bearish sentiment in the short term.
- Analyst Rating Changes: Despite an average price target of $61.50 and a “Buy” rating, recent downgrades from multiple firms suggest growing concerns about the company's future growth potential.
See More
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- New Drug Development Progress: Regeneron will present Phase 3 clinical trial data for two first-in-class antibodies targeting cat and birch allergies at the 2026 AAAAI Annual Meeting, marking a significant innovation potential in allergy treatment that could change existing therapeutic paradigms.
- Dupixent® New Data Release: Newly released data on Dupixent (dupilumab) highlights its clinical and real-world impact across dermatological, respiratory, and gastrointestinal diseases, particularly in analyzing food allergy sensitization in children with atopic dermatitis, showcasing its broad indications and market potential.
- Registration Trial Plans: Based on Phase 3 trial results, Regeneron plans to initiate additional registration trials this year to further validate the efficacy of treatments for cat and birch allergies, which not only strengthens the company's R&D pipeline but also paves the way for future market launches.
- Long-term Efficacy Analysis: Long-term efficacy analyses of Dupixent show that early sustained treatment significantly reduces IgE levels in children, and in adult asthma patients, early use of Dupixent may decrease exacerbations and corticosteroid use, further solidifying its position in treatment regimens.
See More
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- Significant Revenue Growth: Regeneron achieved a 10% revenue growth in Q4 2024, reaching $3.8 billion, primarily driven by strong performances from Dupixent, Libtayo, and EYLEA, demonstrating the company's sustained competitiveness in the biopharmaceutical sector.
- Expansion of Dupixent Patient Base: Over 1 million patients are currently on Dupixent treatment globally, with significant future growth potential anticipated from new indications like COPD, further solidifying its market leadership.
- EYLEA HD Market Performance: EYLEA HD reported net sales of $305 million in Q4, and despite competitive pressures, upcoming launches of a prefilled syringe and label expansions are expected to position it as the new standard in the anti-VEGF category.
- Capital Return Strategy: Regeneron announced the initiation of a quarterly cash dividend program at $0.88 per share and an additional $3 billion share repurchase authorization, reflecting confidence in future cash flows while maintaining ongoing investments in R&D.
See More
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- Revenue Growth Highlight: Regeneron reported total revenues of $3.72 billion for Q3, reflecting an 11% year-over-year increase, primarily driven by higher collaboration revenues with Sanofi, showcasing the company's robust performance in the biopharmaceutical sector.
- Dupixent Sales Milestone: Dupixent achieved global sales of $3.8 billion, a 24% increase, with over 1 million patients currently on treatment, and is expected to continue driving revenue growth, particularly with new indications like COPD.
- EYLEA HD Market Performance: Combined net sales for EYLEA HD and EYLEA reached $1.54 billion, up 3% year-over-year, maintaining a 44% market share despite competitive pressures, indicating strong trust from physicians and patients.
- Pipeline Outlook: Regeneron has approximately 40 programs in clinical development, with several pivotal data readouts anticipated in the next 12 to 18 months, further enhancing the company's potential for medium- to long-term shareholder value growth.
See More
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- Positive Financial Performance: The company’s recent adjustments indicate strong financial performance and confidence in future growth.
See More
