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PYPD Overview

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Intellectia

Loading chart...

High
4.420
Open
4.360
VWAP
4.38
Vol
54.26K
Mkt Cap
83.78M
Low
4.330
Amount
237.65K
EV/EBITDA(TTM)
--
Total Shares
19.08M
EV
71.83M
EV/OCF(TTM)
--
P/S(TTM)
--
Polypid Ltd is a biopharmaceutical company at the clinical stage, based in Israel . The company focuses on the development, production and commercialization of new, locally administered therapies to improve surgical results. The main product is PLEX technology, which is located in the place of surgery and ensures controlled and continuous delivery of medicines.
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Events Timeline

(ET)
2026-03-17
08:50:00
PolyPid Granted FDA Waiver of $4.3M PDUFA Fee
select
2026-02-11 (ET)
2026-02-11
07:40:00
PolyPid CEO: 2026 Will Be a Transformative Year
select
2025-12-16 (ET)
2025-12-16
08:41:00
PolyPid Appoints Brooke Story as Chairman of the Board
select
2025-12-03 (ET)
2025-12-03
08:40:00
PolyPid Receives FDA Meeting Minutes Supporting NDA for D-PLEX100
select
2025-11-12 (ET)
2025-11-12
07:35:25
PolyPid anticipates sufficient cash reserves extending through 2026
select
2025-11-12
07:34:53
PolyPid Announces Q3 Earnings Per Share of 37 Cents, Below Consensus Estimate of 52 Cents
select
2025-09-16 (ET)
2025-09-16
08:41:43
PolyPid Finishes GMP Inspection by Israeli Ministry of Health
select

News

Newsfilter
8.5
03-31Newsfilter
PolyPid Submits NDA for D-PLEX₁₀₀ to Prevent Surgical Infections
  • NDA Submission: PolyPid has submitted a New Drug Application for D-PLEX₁₀₀ to the FDA, aimed at preventing surgical site infections in colorectal surgery patients, marking a pivotal step into the regulatory approval phase with further submissions expected in Q2 2026.
  • Successful Clinical Trials: D-PLEX₁₀₀ demonstrated a significant 60% relative risk reduction (p=0.0013) in surgical site infections in the Phase 3 SHIELD II trial, providing robust clinical data that enhances its market competitiveness.
  • Fast Track Designation: The drug has received FDA's Fast Track designation, allowing for rolling review, which enables PolyPid to expedite its product launch to meet urgent market needs for effective infection prevention therapies.
  • Commercial Partnership Negotiations: PolyPid is actively pursuing negotiations for a U.S. commercialization partnership, aiming to accelerate the market introduction of D-PLEX₁₀₀ through strategic collaborations, thereby enhancing the company's influence in the biopharmaceutical sector.
Newsfilter
1.0
02-25Newsfilter
PolyPid to Participate in Upcoming Investor Conferences
  • Investor Conference Schedule: PolyPid will participate in the Citizens Life Sciences Conference on March 10, 2026, in Miami, which is expected to attract significant investor interest and enhance the company's visibility in the biopharmaceutical sector.
  • Event Details: Additionally, PolyPid will attend the 38th Annual ROTH Conference on March 23, 2026, at the Ritz-Carlton in Dana Point, California, showcasing the market potential of its innovative drugs.
  • Product Development Progress: PolyPid's lead product, D-PLEX₁₀₀, successfully met all primary and key secondary endpoints in the SHIELD II trial, demonstrating its effectiveness in preventing surgical site infections and solidifying the company's competitive position in the industry.
  • Company Vision and Mission: As a biopharmaceutical company dedicated to enhancing treatment effectiveness, PolyPid aims to address critical medical needs in surgical care and metabolic diseases through the development of long-acting controlled-release drugs, thereby raising the standard of patient care.
seekingalpha
9.5
02-11seekingalpha
PolyPid Ltd. Q4 2025 Earnings Call Insights
  • Key Trial Success: PolyPid completed the SHIELD II Phase III trial in 2025, with D-PLEX100 demonstrating a significant reduction in surgical site infections, achieving all primary and key secondary endpoints, marking a major advancement in the medical technology sector.
  • Regulatory Progress: Recent positive feedback from the FDA supports PolyPid's plan to initiate a rolling NDA submission for D-PLEX100 by the end of Q1 2026, indicating that the existing clinical data package is adequate for NDA submission and review, boosting market confidence.
  • Improved Financials: R&D expenses for Q4 2025 were $6.2 million, down from $7 million in the same period last year, while net loss remained at $8.5 million, with loss per share decreasing from $1.13 to $0.41, reflecting the company's efforts in cost control.
  • Strategic Partnership Advancement: Management noted that discussions with U.S. partners have reached advanced stages, with 2026 expected to be a transformative year for the company, emphasizing the clinical value and market potential of D-PLEX100.
seekingalpha
9.5
02-11seekingalpha
PolyPid Q4 Earnings Miss Expectations with GAAP EPS of -$0.41
  • Earnings Report Shortfall: PolyPid's Q4 GAAP EPS of -$0.41 misses expectations by $0.08, indicating challenges in profitability that may affect investor confidence and market perception.
  • Cash Flow Status: As of December 31, 2025, the company reported cash, cash equivalents, and short-term deposits of $12.9 million, down from $15.6 million in the previous year, reflecting pressure on financial management and liquidity.
  • Operational Funding Outlook: The company believes its current cash balance will be sufficient to fund operations into the second half of 2026, despite the risk of declining funds, indicating a strategic approach to navigating upcoming milestones.
  • Future Development Potential: PolyPid is actively advancing the D-PLEX100 project aimed at tackling surgical site infections, which, if successful, could significantly enhance the company's market competitiveness and profitability in the healthcare sector.
Newsfilter
8.5
02-11Newsfilter
PolyPid Advances D-PLEX100 Commercialization Efforts
  • Partnership Progress: PolyPid is advancing discussions with potential U.S. partners for D-PLEX₁₀₀, having moved into advanced stages, indicating strong market recognition and demand, which is expected to accelerate revenue growth for the company.
  • Positive Regulatory Feedback: The company received favorable feedback from the FDA during the pre-NDA meeting, with plans to initiate a rolling NDA submission by the end of Q1 2026, paving the way for market access and enhancing competitiveness in the surgical site infection prevention sector.
  • Improved Financial Performance: R&D expenses for Q4 2025 decreased to $6.2 million from $7.0 million in Q4 2024, reflecting the completion of the SHIELD II Phase 3 trial, which is expected to improve the company's financial health and bolster investor confidence.
  • Leadership Change: The appointment of Brooke Story as Chair of the Board brings extensive experience in medical technology and surgical solutions, which is anticipated to enhance the company's governance structure and strategic execution capabilities.
NASDAQ.COM
5.0
2025-12-16NASDAQ.COM
PolyPid Names Brooke Story as Board Chairman
  • Appointment Announcement: PolyPid Ltd. has appointed Brooke Story as Chairman of the Board of Directors, effective December 11, 2025.

  • Expertise and Experience: Brooke Story brings over 25 years of leadership experience in the MedTech industry, having held senior roles at BD and Medtronic, and is expected to leverage her expertise in surgical infection prevention.

  • CEO's Statement: CEO Dikla Czaczkes Akselbrad highlighted Story's appointment as a pivotal moment for PolyPid, emphasizing her role in transforming clinical success into commercial reality.

  • Current Roles: In addition to her new position at PolyPid, Ms. Story serves as a non-executive director on the Board of LivaNova PLC.

Wall Street analysts forecast PYPD stock price to rise
3 Analyst Rating
Wall Street analysts forecast PYPD stock price to rise
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
9.00
Averages
11.00
High
13.00
Current: 0.000
sliders
Low
9.00
Averages
11.00
High
13.00
Roth Capital
Buy
downgrade
$10 -> $9
AI Analysis
2025-11-13
Reason
Roth Capital
Price Target
$10 -> $9
AI Analysis
2025-11-13
downgrade
Buy
Reason
Roth Capital lowered the firm's price target on PolyPid to $9 from $10 and keeps a Buy rating on the shares following the Q3 report. The firm expects a positive pre-new drug application meeting and a potential filing submission in the first half of 2026 for PolyPid. Given that D-PLEX100 "enjoys multiple designations" from the FDA, it should get a six-month review, the analyst tells investors in a research note.
Roth Capital
Buy
maintain
$9 -> $10
2025-08-14
Reason
Roth Capital
Price Target
$9 -> $10
2025-08-14
maintain
Buy
Reason
Roth Capital raised the firm's price target on PolyPid to $10 from $9 and keeps a Buy rating on the shares after meeting with its management following the company's Q2 results. The firm expects a fairly uneventful pre-NDA meeting given solid D-PLEX100 clinical data, which Roth believes is poised to transform the treatment paradigm in SSI associated with colorectal cancer surgery, providing benefits to patients and healthcare systems, the analyst tells investors in a research note.
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Valuation Metrics

The current forward P/E ratio for PolyPid Ltd (PYPD.O) is 0.00, compared to its 5-year average forward P/E of -1.78. For a more detailed relative valuation and DCF analysis to assess PolyPid Ltd's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.78
Current PE
0.00
Overvalued PE
-0.61
Undervalued PE
-2.94

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.62
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.29
Undervalued EV/EBITDA
-1.52

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
47.15
Current PS
3.58
Overvalued PS
244.58
Undervalued PS
-150.28

Financials

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Frequently Asked Questions

What is PolyPid Ltd (PYPD) stock price today?

The current price of PYPD is 4.39 USD — it has increased 0

What is PolyPid Ltd (PYPD)'s business?

Polypid Ltd is a biopharmaceutical company at the clinical stage, based in Israel . The company focuses on the development, production and commercialization of new, locally administered therapies to improve surgical results. The main product is PLEX technology, which is located in the place of surgery and ensures controlled and continuous delivery of medicines.

What is the price predicton of PYPD Stock?

Wall Street analysts forecast PYPD stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PYPD is11.00 USD with a low forecast of 9.00 USD and a high forecast of 13.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is PolyPid Ltd (PYPD)'s revenue for the last quarter?

PolyPid Ltd revenue for the last quarter amounts to -8.53M USD, increased 3.76

What is PolyPid Ltd (PYPD)'s earnings per share (EPS) for the last quarter?

PolyPid Ltd. EPS for the last quarter amounts to USD, decreased

How many employees does PolyPid Ltd (PYPD). have?

PolyPid Ltd (PYPD) has 69 emplpoyees as of April 04 2026.

What is PolyPid Ltd (PYPD) market cap?

Today PYPD has the market capitalization of 83.78M USD.