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OKUR

Onkure Therapeutics Inc
$
1.920
-0.080(-4.000%)
  • Overview
  • Forecast
  • Valuation
Line
Line
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Candle
Candle
1D
5D
1M
3M
6M
YTD
1Y
5Y
High
2.050
Open
1.990
VWAP
1.92
Vol
185.91K
Mkt Cap
25.94M
Low
1.830
Amount
357.08K
EV/EBITDA(TTM)
--
Total Shares
13.51M
EV
-70.72M
EV/OCF(TTM)
--
P/S(TTM)
--
OnKure Therapeutics, Inc., formerly Reneo Pharmaceuticals, Inc., is a clinical-stage biopharmaceutical company focused on the discovery and development of precision medicines that target biologically validated drivers of cancers that are underserved by available therapies. Using a structure-based drug design platform, the Company is building a robust pipeline of tumor-agnostic candidates. The Company is developing OKI-219, a selective PI3KαH1047R inhibitor, as its lead program. OKI-219 is being evaluated in a Phase I clinical trial in solid tumor patients with PI3KαH1047R mutations, including breast cancer. The Company is also focused on targeting oncogenic PI3Kα and has multiple programs designed to enable targeting of this key oncogene.
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5 Analyst Rating
up Image
1553.65% Upside
Wall Street analysts forecast OKUR stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for OKUR is 31.75 USD with a low forecast of 30.00 USD and a high forecast of 34.00  USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
5 Buy
0 Hold
0 Sell
Strong Buy
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1553.65% Upside
Current: 1.920
sliders
Low
30.00
Averages
31.75
High
34.00
HC Wainwright & Co.
Robert Burns
Strong Buy
Maintains
$40 → $34
2025-03-18
Reason
Oppenheimer
Matt Biegler
Buy
Maintains
$35 → $30
2025-03-11
Reason
Oppenheimer lowered the firm's price target on OnKure Therapeutics to $30 from $35 but keeps an Outperform rating on the shares after its Q4 results. The firm's post-earnings discussion with the company revealed that an important update from PIKture-01 is slated for the second half of 2025 and should provide enough data to make a determination on OKI-219's competitive profile relative to RLY-2608 and STX-478, the analyst tells investors in a research note. While OKI-219 is ultra-selective for common H1047R mutant, the company is also being more vocal about its pan-mutant inhibitor pipeline, the firm adds.
Jones Trading
Soumit Roy
Strong Buy
Initiates
$32
2025-01-28
Reason
JonesResearch initiated coverage of OnKure Therapeutics (OKUR) with a Buy rating and $32 price target. The clinical stage precision oncology company is developing targeted PI3Kalpha inhibitors for the treatment of breast cancer and other solid tumors with mutations in the PIK3CA gene, notes the analyst, who points out that this space has come under spotlight recently following the acquisition of Scorpion Therapeutics by Eli Lilly (LLY) in January for up to $2.5B. OnKure's lead asset, OKI-219, is a small molecule point-mutation specific inhibitor that targets PI3Kalpha harboring a H1047R mutation, notes the analyst, who adds that OKI-219 has "the potential to be the first approved mutation-specific PI3Kalpha inhibitor."
Leerink Partners
Andrew Berens
Buy
Initiates
$33
2024-12-05
Reason
HC Wainwright & Co.
Robert Burns
Strong Buy
Reiterates
$40
2024-11-08
Reason
HC Wainwright & Co.
Robert Burns
Strong Buy
Initiates
$40
2024-10-17
Reason

Valuation Metrics

The current forward P/E ratio for Onkure Therapeutics Inc (OKUR.O) is -0.44, compared to its 5-year average forward P/E of -2.42. For a more detailed relative valuation and DCF analysis to assess Onkure Therapeutics Inc 's fair value, click here.

Forward PE

StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.42
Current PE
-0.44
Overvalued PE
-0.22
Undervalued PE
-4.62

Forward EV/EBITDA

StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
45.21
Current PS
161.20
Overvalued PS
112.16
Undervalued PS
-21.75

Financials

Annual
Quarterly
FY2025Q1
YoY :
+72.92%
-17.00M
Operating Profit
FY2025Q1
YoY :
+67.00%
-15.93M
Net Income after Tax
FY2025Q1
YoY :
-96.08%
-1.19
EPS - Diluted
FY2025Q1
YoY :
+31.82%
-14.02M
Free Cash Flow

Trading Trends

Insider
Insiders are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
11.8K
USD
4
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Hedge Fund
Hedge Funds are Neutral. There are no significant trading trends over the last quarter.
Sold
0-3
Months
0.0
Volume
0
3-6
Months
8.2M
Volume
1
6-9
Months
0.0
Volume
0
0-12
Months
0.0
Volume
0
Bought
0-3
0
0.0
Volume
Months
3-6
5
4.5M
Volume
Months
6-9
0
0.0
Volume
Months
0-12
0
0.0
Volume
Months
Congress Trading
Congress are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months

OKUR News & Events

Events Timeline

2025-05-06 (ET)
2025-05-06
07:32:55
OnKure Therapeutics sees cash runway into 4Q26
select
2025-05-06
07:32:00
OnKure Therapeutics reports Q1 EPS ($1.19), consensus ($1.38)
select
2025-03-10 (ET)
2025-03-10
20:49:22
OnKure Therapeutics reports Q4 EPS ($1.37), consensus (86c)
select
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News

9.5
05-06Newsfilter
OnKure Therapeutics Reports First Quarter 2025 Financial Results and Business Highlights
6.0
03-11Benzinga
Gilead Sciences To Rally Around 11%? Here Are 10 Top Analyst Forecasts For Tuesday
4.0
03-10Business Insider
Analysts Offer Insights on Healthcare Companies: OnKure Therapeutics (OKUR) and EyePoint Pharmaceuticals (EYPT)
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FAQ

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What is Onkure Therapeutics Inc (OKUR) stock price today?

The current price of OKUR is 1.92 USD — it has decreased -4 % in the last trading day.

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