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MNOV Overview

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Intellectia

Loading chart...

High
1.370
Open
1.370
VWAP
1.36
Vol
35.22K
Mkt Cap
66.94M
Low
1.340
Amount
47.78K
EV/EBITDA(TTM)
--
Total Shares
49.22M
EV
39.61M
EV/OCF(TTM)
--
P/S(TTM)
--
MediciNova, Inc. is a biopharmaceutical company that is developing therapeutics with a primary focus on neurology, respiratory and liver diseases. The Company's development activities are focused on MN-166 (ibudilast) for neurological and other disorders such as progressive multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), chemotherapy-induced peripheral neuropathy, degenerative cervical myelopathy, glioblastoma, substance dependence and addiction (methamphetamine dependence, opioid dependence and alcohol dependence), prevention of acute respiratory distress syndrome, and Long COVID, and MN-001 (tipelukast) for fibrotic and other metabolic disorders such as nonalcoholic fatty liver disease and hypertriglyceridemia. Its MN-166 (ibudilast) is a first-in-class, oral, anti-inflammatory and neuroprotective agent. The FDA has granted Fast Track designations to MN-166 (ibudilast) for three separate indications: progressive MS, ALS, and methamphetamine dependence.
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Events Timeline

(ET)
2026-04-27
19:20:00
MediciNova Collaborates with Tokyo Stock Exchange on Brain Metastasis Research
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2026-01-29 (ET)
2026-01-29
18:10:00
MediciNova Enrolls 100 Patients in ALS Study
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2026-01-06 (ET)
2026-01-06
09:20:00
MediciNova CEO Updates Shareholders, Looks Ahead to 2026
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2025-12-18 (ET)
2025-12-18
06:10:00
MediciNova Completes Patient Enrollment in OXTOX Study
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News

NASDAQ.COM
9.0
05-27NASDAQ.COM
MediciNova Completes Last Patient Visit in Phase 2 Trial of MN-001
  • Clinical Trial Progress: MediciNova announced the completion of the last patient visit in its Phase 2 trial of MN-001 for treating hypertriglyceridemia and non-alcoholic fatty liver disease in type-2 diabetes patients, marking a significant milestone in the drug's development.
  • Trial Design and Objectives: The trial is a multicenter, randomized, double-blind, placebo-controlled study lasting 24 weeks, primarily assessing the impact of MN-001 on liver fat content and serum triglycerides, with topline results expected in Q3 2026, potentially influencing treatment strategies for diabetes-related conditions.
  • Drug Mechanism and Potential: MN-001 is a novel small molecule compound exhibiting anti-inflammatory and anti-fibrotic activity by inhibiting fibrosis pathways and down-regulating pro-inflammatory genes, showing promising results in preclinical models, which could provide new treatment options for diabetic patients if successful.
  • Other R&D Updates: In addition to MN-001, MediciNova is advancing Phase 2 trials for idiopathic pulmonary fibrosis and non-alcoholic fatty liver disease, while its lead candidate MN-166 is undergoing Phase 3 studies for amyotrophic lateral sclerosis and other conditions, demonstrating the company's diversified strategy in the biopharmaceutical sector.
Newsfilter
9.0
05-26Newsfilter
MediciNova Completes Last Patient Visit in MN-001 Clinical Trial
  • Clinical Trial Progress: MediciNova announced the completion of the last patient visit in its Phase 2 clinical trial MN-001-NATG-202 for MN-001 (tipelukast) targeting hypertriglyceridemia and nonalcoholic fatty liver disease associated with type 2 diabetes, marking a significant milestone as the study moves into critical data analysis, with top-line results expected in Q3 2026, potentially impacting the company's future market performance positively.
  • Trial Design Details: The study is a multicenter, randomized, double-blind, placebo-controlled trial where patients are randomized 1:1 to receive either 500 mg/day of MN-001 or placebo for 24 weeks, primarily assessing changes in liver fat content and fasting serum triglycerides, which will provide crucial evidence for the efficacy of MN-001.
  • Drug Mechanism Exploration: MN-001 is believed to exert anti-inflammatory and antifibrotic effects through various mechanisms, including leukotriene receptor antagonism and phosphodiesterase inhibition, with research indicating its ability to down-regulate genes promoting fibrosis and inflammation; positive clinical outcomes could offer new treatment options and enhance the company's competitive edge in the biopharmaceutical sector.
  • Market Potential Analysis: Given the high prevalence of hypertriglyceridemia and NAFLD among type 2 diabetes patients, successful development of MN-001 could not only improve patient quality of life but also open new revenue streams for MediciNova, further solidifying its position in the biopharmaceutical industry.
Newsfilter
2.0
04-27Newsfilter
MediciNova Study Reveals New Target for Brain Metastasis
  • New Target Discovery: Research from the Spanish National Cancer Research Centre identifies macrophage migration inhibitory factor (MIF)-mediated reprogramming of CD74-positive microglia and macrophages as a central vulnerability in brain metastasis, highlighting the therapeutic potential of pharmacological modulation of the MIF-CD74 signaling pathway.
  • Efficacy of Ibudilast: The study demonstrates that ibudilast effectively blocks MIF-CD74 signaling, reverses pro-metastatic immune reprogramming, and suppresses brain metastasis growth in preclinical systems, potentially offering new strategies for neuro-oncology treatments.
  • Biomarker Potential: The research also identifies secreted MIF as a candidate liquid biopsy biomarker detectable in cerebrospinal fluid, supporting biomarker-guided clinical strategies that could enhance treatment outcomes for patients with brain metastases.
  • Future Clinical Collaboration: MediciNova plans to collaborate with Dr. Valiente and CNIO on clinical research targeting patients with brain metastases, aiming to address significant unmet medical needs, particularly for common metastatic cancers such as lung and breast cancer.
NASDAQ.COM
9.0
01-30NASDAQ.COM
MediciNova's SEANOBI Study Reaches 50% Enrollment Milestone
  • Study Progress: MediciNova's SEANOBI study has enrolled 50% of its target 200 participants, indicating significant clinical research advancement in ALS, which may provide new treatment options for patients.
  • Funding Support: The study is backed by a $22 million NIH grant aimed at accelerating access to therapies for ALS patients, reflecting government commitment to this research area and confidence in MediciNova.
  • Clinical Trials: The ongoing COMBAT ALS trial for MN-166 has enrolled 234 patients, with top-line results expected by the end of 2026, which will provide critical efficacy data that could influence future market performance.
  • Drug Development: In addition to ALS, MN-166 is being developed for glioblastoma, Long COVID, chemotherapy-induced peripheral neuropathy, and substance use disorder, showcasing its broad potential indications that could diversify the company's revenue streams.
Newsfilter
2.0
01-29Newsfilter
MediciNova Activates SEANOBI Study with 100 Patient Enrollments
  • Patient Enrollment Progress: As of the end of January 2026, MediciNova has successfully enrolled 100 ALS patients across 12 sites in the U.S., achieving 50% of the planned 200 enrollments, marking significant progress in the clinical development of MN-166 and potentially accelerating the drug approval process.
  • Funding Support: The SEANOBI Expanded Access Program is backed by a $22 million NINDS grant, designed to provide MN-166 treatment access to ALS patients not eligible for ongoing randomized trials while collecting crucial clinical and biomarker data, enhancing the drug's market competitiveness.
  • Clinical Trial Design: MN-166 is also undergoing the COMBAT-ALS Phase 2b/3 randomized controlled trial, with 234 patients enrolled in the U.S. and Canada, and top-line results expected by the end of 2026, which will provide essential evidence for the drug's future approval.
  • Strategic Implications: MediciNova's MN-166 has received Orphan Drug Designation from the FDA and EMA, along with Fast Track Designation from the FDA, and the combined clinical data from SEANOBI and COMBAT-ALS will offer more treatment options for ALS patients, addressing the urgent market demand for new therapies.
NASDAQ.COM
2.0
2025-12-19NASDAQ.COM
Biotech Surge Post-Market: Inspira, MediciNova, and DiaMedica Therapeutics Among Top Performers
  • Biotech Stocks Performance: Several small-cap biotech and healthcare companies saw notable gains in after-hours trading, driven by recent corporate updates and clinical milestones.

  • Inspira Technologies Update: Inspira Technologies Oxy B.H.N. Ltd. rose 5.88% following a recent agreement for a registered direct offering and a Standby Equity Purchase Agreement, despite no new news on the day.

  • MediciNova's Clinical Trial Success: MediciNova, Inc. advanced 4.83% after successfully completing patient enrollment in its Phase 2 OXTOX study, which evaluates MN-166 for preventing chemotherapy-induced peripheral neuropathy.

  • DiaMedica's FDA Meeting: DiaMedica Therapeutics Inc. gained 2.89% after a productive pre-IND meeting with the FDA regarding its study of DM199 in preeclampsia, with an additional non-clinical study requested.

Wall Street analysts forecast MNOV stock price to rise
1 Analyst Rating
Wall Street analysts forecast MNOV stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
11.00
Averages
11.00
High
11.00
Current: 0.000
sliders
Low
11.00
Averages
11.00
High
11.00
Maxim
Michael Okunewitch
Buy
initiated
$6
AI Analysis
2026-03-23
Reason
Maxim
Michael Okunewitch
Price Target
$6
AI Analysis
2026-03-23
initiated
Buy
Reason
Maxim analyst Michael Okunewitch resumed coverage of MediciNova with a Buy rating and $6 price target. The firm is positive on the company's potential value-driving data events in 2026, including a Phase 2b/3 study in Amyotrophic Lateral Sclerosis that could be used to support NDA filing and a Phase 2 in the metabolic diseases space, which has been one of the most active and high-value spaces across biotech in recent year, the analyst tells investors in a research note. MediciNova also has pipeline programs related to its two lead assets that could potentially find partners, which could bring in non-dilutive capital and extend the runway, the firm added.
Maxim
NULL -> Buy
initiated
$6
2026-03-23
Reason
Maxim
Price Target
$6
2026-03-23
initiated
NULL -> Buy
Reason
Maxim resumed coverage of MediciNova with a Buy rating and $6 price target.
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Valuation Metrics

The current forward P/E ratio for MediciNova Inc (MNOV.O) is 8.53, compared to its 5-year average forward P/E of -5.24. For a more detailed relative valuation and DCF analysis to assess MediciNova Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.24
Current PE
8.53
Overvalued PE
-0.46
Undervalued PE
-10.02

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
50.40
Current EV/EBITDA
4511.45
Overvalued EV/EBITDA
590.51
Undervalued EV/EBITDA
-489.72

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
54.22
Current PS
163.66
Overvalued PS
165.06
Undervalued PS
-56.61

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Whales Holding MNOV

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3D Investment Partners Pte. Ltd
Holding
MNOV
-3.55%
3M Return

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Frequently Asked Questions

What is MediciNova Inc (MNOV) stock price today?

The current price of MNOV is 1.36 USD — it has decreased -0.73

What is MediciNova Inc (MNOV)'s business?

MediciNova, Inc. is a biopharmaceutical company that is developing therapeutics with a primary focus on neurology, respiratory and liver diseases. The Company's development activities are focused on MN-166 (ibudilast) for neurological and other disorders such as progressive multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), chemotherapy-induced peripheral neuropathy, degenerative cervical myelopathy, glioblastoma, substance dependence and addiction (methamphetamine dependence, opioid dependence and alcohol dependence), prevention of acute respiratory distress syndrome, and Long COVID, and MN-001 (tipelukast) for fibrotic and other metabolic disorders such as nonalcoholic fatty liver disease and hypertriglyceridemia. Its MN-166 (ibudilast) is a first-in-class, oral, anti-inflammatory and neuroprotective agent. The FDA has granted Fast Track designations to MN-166 (ibudilast) for three separate indications: progressive MS, ALS, and methamphetamine dependence.

What is the price predicton of MNOV Stock?

Wall Street analysts forecast MNOV stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MNOV is11.00 USD with a low forecast of 11.00 USD and a high forecast of 11.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is MediciNova Inc (MNOV)'s revenue for the last quarter?

MediciNova Inc revenue for the last quarter amounts to 186.98K USD, decreased

What is MediciNova Inc (MNOV)'s earnings per share (EPS) for the last quarter?

MediciNova Inc. EPS for the last quarter amounts to -0.05 USD, decreased -16.67

How many employees does MediciNova Inc (MNOV). have?

MediciNova Inc (MNOV) has 6 emplpoyees as of May 31 2026.

What is MediciNova Inc (MNOV) market cap?

Today MNOV has the market capitalization of 66.94M USD.