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Access earnings results, analyst expectations, report, slides, earnings call, and transcript.
The earnings call presents mixed signals. While strategic partnerships and other revenue increased significantly, core areas like PYLARIFY and Precision Diagnostics remained flat. The company faces competitive challenges and has reduced its EPS guidance, indicating potential short-term struggles. However, optimistic long-term growth potential in the Alzheimer's diagnostic market and strategic transactions could offset these concerns. The market reaction is likely to be neutral, reflecting the balance between short-term challenges and long-term optimism.
Consolidated Net Revenue $372.8 million, an increase of 0.8% year-over-year.
Radiopharmaceutical Oncology Revenue (PYLARIFY) $257.7 million, flat year-over-year.
Precision Diagnostics Revenue $104.4 million, flat year-over-year.
DEFINITY Sales $79.2 million, an increase of 3.5% year-over-year.
TechneLite Revenue $19.7 million, a decrease of 9.2% year-over-year due to a brief supply issue.
Strategic Partnerships and Other Revenue $10.7 million, an increase of 65.1% year-over-year due to contributions from MK-6240 and a sale milestone.
Gross Profit Margin 67%, a decrease of 180 basis points year-over-year due to strategic partnership contracting initiatives and unfavorable dose volume mix.
Operating Expenses 28.3% of net revenue, an increase of 147 basis points year-over-year due to investments in growth and efficiency initiatives.
Operating Profit $144.3 million, a decrease of 7.1% year-over-year.
GAAP Net Income $72.9 million, a decrease of 7.5% year-over-year.
Adjusted Net Income $109.5 million, a decrease of 7.5% year-over-year.
GAAP EPS $1.02, a decrease of 9.5% year-over-year.
Adjusted EPS $1.53, a decrease of 9.5% year-over-year.
Operating Cash Flow $107.6 million, down $19.7 million year-over-year.
Capital Expenditures $8.7 million, $400,000 lower year-over-year.
Free Cash Flow $98.8 million, down $20.1 million year-over-year.
Cash and Cash Equivalents $938.5 million at the end of Q1.
Effective Tax Rate 26.5%.
New Product Launches: Lantheus announced the acquisition of Life Molecular Imaging (LMI), which includes NEURACEQ, a PET imaging agent for Alzheimer’s disease. Evergreen Theragnostics acquisition includes OCTEVY, a PET imaging agent targeting neuroendocrine tumors.
Sales Performance: PYLARIFY sales for Q1 2025 were $258 million, with a year-over-year volume growth. DEFINITY achieved approximately $79 million in sales in Q1 2025.
Market Expansion: The U.S. Alzheimer’s radiodiagnostics market is projected to grow to over $1.5 billion by the end of the decade. The PSMA PET addressable market is anticipated to exceed $3.5 billion by 2030.
Operational Efficiency: The acquisition of Evergreen enhances manufacturing infrastructure and development timelines. Lantheus plans to invest further in the Evergreen facility to improve radiodiagnostic expertise.
Strategic Shift: Lantheus announced the divestment of its SPECT business to SHINE Technologies to focus on PET radiodiagnostics. The company is integrating the Evergreen and LMI businesses to streamline operations and enhance growth.
Earnings Expectations: Lantheus Holdings, Inc. missed earnings expectations with a reported EPS of $1.53 compared to the expected $1.68, indicating potential financial performance risks.
Competitive Pressures: The company anticipates competitive disruption among smaller, non-contracted sites due to the expiry of PYLARIFY pass-through status and the implementation of mean unit cost payment for Medicare, which may affect revenue.
Regulatory Issues: The company is actively monitoring recent tariff activity that could impact their business, although currently, the direct impact is considered minimal.
Supply Chain Challenges: There was a brief supply issue with TechneLite, which affected revenue, although it has since been resolved.
Acquisition Risks: The integration of acquired companies (Evergreen and LMI) poses risks related to operational efficiency and the realization of projected synergies.
Market Growth Uncertainty: While the Alzheimer’s radiodiagnostic market is expected to grow significantly, the actual realization of this growth is contingent on the approval of numerous therapeutics currently in development.
R&D Investment Risks: Increased R&D expenses (up to 7.5% of revenue) may impact short-term profitability, especially if anticipated projects do not yield expected returns.
Patent Litigation: The launch of PNT2003 is pending positive resolution to ongoing patent litigation, which poses a risk to its market entry.
Divestiture of SPECT Business: Lantheus announced plans to divest its SPECT business to SHINE Technologies, focusing on PET radiodiagnostics, microbubbles, and radiotherapeutic agents.
Acquisitions of Evergreen and LMI: The acquisitions are aimed at enhancing radiopharmaceutical leadership, diversifying revenue, and adding capabilities for novel programs.
Revenue Growth Drivers: The acquisitions are expected to add immediate revenue growth drivers and enhance the company's long-term growth potential.
R&D Investments: R&D investments are projected to be approximately 7.5% of revenue, reflecting a focus on late- and early-stage development programs.
2025 Revenue Guidance: Revenue is now expected to be between $1.55 billion to $1.585 billion, with PYLARIFY performance adjusted to flat-to-low single-digit percent growth.
Adjusted EPS Guidance: Adjusted EPS is projected in the range of $6.60 to $6.70, down from the prior guidance of $7 to $7.20.
Impact of Acquisitions on EPS: The acquisitions of Evergreen and LMI are expected to reduce adjusted EPS by approximately $0.25.
Future Growth Potential: The divestiture of the SPECT business is expected to unlock consolidated revenue growth and gross margin expansion in the future.
Shareholder Return Plan: The company is focused on returning value to shareholders through disciplined capital allocation strategies and investments in capabilities. They expect the divestiture of the SPECT business to unlock consolidated revenue growth and gross margin expansion in the future.
Free Cash Flow: Free cash flow for Q1 2025 was $98.8 million.
Cash Position: Cash and cash equivalents, net of restricted cash, were $938.5 million at the end of Q1.
EPS Guidance: Adjusted EPS is now expected to be in the range of $6.60 to $6.70 for the full year 2025.
The earnings call reveals several negative indicators: reduced revenue guidance, declining gross profit margins, and increased operating expenses. The Q&A section shows management's reluctance to provide specific guidance for 2026, adding uncertainty. Despite some positives like new product launches and a stock repurchase program, the overall sentiment is negative due to financial declines and management changes. These factors, combined with competitive pressures and lack of clear future direction, suggest a likely negative stock price movement.
The earnings call presents a mixed outlook. While there are positive elements such as expected revenue growth from acquisitions and market expansion opportunities, there are concerns regarding declining EPS guidance and pricing pressures on PYLARIFY. The Q&A highlighted uncertainties in contract dynamics and market competition. Despite potential growth in Alzheimer's diagnostics, the flat PYLARIFY growth and the impact of acquisitions on EPS dilute the overall sentiment. The absence of clear guidance on certain aspects further adds to the neutral stance.
The earnings call presents mixed signals. While strategic partnerships and other revenue increased significantly, core areas like PYLARIFY and Precision Diagnostics remained flat. The company faces competitive challenges and has reduced its EPS guidance, indicating potential short-term struggles. However, optimistic long-term growth potential in the Alzheimer's diagnostic market and strategic transactions could offset these concerns. The market reaction is likely to be neutral, reflecting the balance between short-term challenges and long-term optimism.
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