The chart below shows how KYMR performed 10 days before and after its earnings report, based on data from the past quarters. Typically, KYMR sees a -1.35% change in stock price 10 days leading up to the earnings, and a +5.07% change 10 days following the report. On the earnings day itself, the stock moves by +1.17%. This data can give you a slight idea of what to expect for the next quarter's release.
Positive
Phase 1 Study Initiation: We have started the Phase 1 study of KT-621, our first-in-class oral STAT6 degrader, accelerating the path to the clinic given our recent increased focus of resources and capital that we're redirecting towards our growing immunology pipeline.
STAT6 Degrader Efficacy: We have shown in preclinical species that a STAT6 degrader like KT-621 can block IL-4 and 13 similarly or even more potently than an upstream biologics like dupilumab in both cellular and in vivo models.
Strong Cash Position: We ended the quarter with $911 million of cash on our balance sheet, providing a cash runway to mid-2027 and through several inflection points across our pipeline.
Funding Milestone Achieved: We raised a total of approximately $600 million in just 2024, enabling us to have cash into mid-2027 and through several inflection points across our pipeline.
Clinical Activity and Advancement: We have demonstrated a robust clinical activity across different tumor types, completing Phase 1 enrollment, and we have made the decision that we will only advance KT-333, our STAT3 degrader, and KT-253, our MDM2 degrader, beyond Phase 1 with a partner.
Negative
Revenue Decline Reported: In the third quarter of 2024, Kymera reported a revenue of only $3.7 million, which is significantly lower than expected, indicating a decline in financial performance.
R&D and SG&A Spending: Combined spending on R&D and SG&A was $61 million in the quarter, down about 2% sequentially from the previous quarter, reflecting tighter cost management amid declining revenues.
Cash Reserves Reliance: The company ended the quarter with $911 million in cash, which, while substantial, indicates a reliance on existing cash reserves due to low revenue generation.
Clinical Advancement Concerns: Kymera's focus on the KT-621 program has not yet translated into significant clinical advancements, raising concerns about the effectiveness of their product pipeline.
Phase 1 Study Challenges: The ongoing Phase 1 study for KT-621 has not yet yielded any promising results, which could hinder future investment and development opportunities.
Kymera Therapeutics, Inc. (KYMR) Q3 2024 Earnings Call Transcript
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