The earnings call summary reveals several negative indicators: significant net loss increase, operational delays in trial enrollment, and high R&D and G&A expenses. Despite a strong cash position, financial strain is evident due to increased share-based compensation. Additionally, management's unclear responses on SG&A expenses and operational timelines raise concerns. The market cap suggests moderate volatility, leading to a predicted stock price movement in the negative range of -2% to -8% over the next two weeks.