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APGE Overview

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$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

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High
76.490
Open
74.900
VWAP
74.86
Vol
714.36K
Mkt Cap
5.24B
Low
73.400
Amount
53.48M
EV/EBITDA(TTM)
--
Total Shares
69.49M
EV
4.51B
EV/OCF(TTM)
--
P/S(TTM)
--
Apogee Therapeutics, Inc. is a clinical-stage biotechnology company. The Company is advancing novel biologics with the potential for differentiated efficacy and dosing in the inflammatory and immunology (I&I) markets, including for the treatment of atopic dermatitis (AD), asthma, eosinophilic esophagitis (EoE), chronic obstructive pulmonary disease (COPD), and other I&I indications. APG777, the Company’s most advanced program, is being initially developed for the treatment of AD. With four validated targets in its portfolio, it is seeking to achieve efficacy and dosing through monotherapies and combinations of its novel antibodies. Its most advanced programs are APG777, APG990, APG333, and APG808. APG990 is an SQ extended half-life mAb that utilizes advanced antibody engineering to target OX40L. APG333 is a fully human mAb against thymic stromal lymphopoietin (TSLP). APG808 is an SQ extended half-life mAb targeting IL-4Rα. APG279 is for the dual inhibition of OX40L and IL-13.
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Events Timeline

(ET)
2026-03-02
07:11:00
Apogee Therapeutics Advances zumilokibart Development
select
2026-03-02
07:10:00
Apogee Cash and Cash Equivalents Reach $902.9 Million
select
2026-01-23 (ET)
2026-01-23
12:10:00
Apogee Therapeutics Shares Down 13.0% to $69.44
select

News

NASDAQ.COM
9.5
03-03NASDAQ.COM
Apogee Therapeutics Reports 2025 Financial Results and Pipeline Progress
  • Widening Financial Loss: Apogee Therapeutics reported a net loss of $255.8 million for 2025, up from $182.1 million in 2024, indicating ongoing pressure from R&D investments that may affect future financing capabilities.
  • Pipeline Strategy Focus: The company employs a 'pipeline-in-a-product' strategy centered on Zumilokibart, with multiple pivotal data readouts expected in 2026, which will significantly impact its market positioning and investor confidence.
  • Clinical Trial Progress: The APEX Phase 2 trial for Zumilokibart is set to release 52-week Part A data this month, while 16-week Part B data is anticipated in Q2 2026, with successful results paving the way for Phase 3 initiation.
  • Strong Cash Position: Apogee ended 2025 with a robust cash reserve of $902.9 million, providing a runway into the second half of 2028, thereby supporting the advancement toward the launch of Zumilokibart in 2029.
seekingalpha
9.5
03-02seekingalpha
Apogee Therapeutics Reports FY Net Loss of $255.8M
  • Financial Performance: Apogee Therapeutics reported a net loss of $255.8 million for FY 2023, indicating high expenditures in R&D and marketing that could negatively impact future financing capabilities and shareholder confidence.
  • Clinical Progress: The company has made advancements in the interim Phase Ib results of Zumilokibart for mild-to-moderate asthma, although specific data was not disclosed; this progress may lay the groundwork for future product launches and enhance market competitiveness.
  • Strategic Outlook: Apogee Therapeutics is viewed as reaching a critical inflection point in immunology by 2026, and successful new therapy launches could improve financial health and attract more investor interest.
  • Industry Engagement: The company presented at the 2025 Citi Annual Global Healthcare Conference, and while detailed outcomes were not provided, such events help raise brand awareness and may facilitate future collaboration opportunities.
Fool
8.5
02-25Fool
Great Point Partners Increases Stake in Apogee Therapeutics
  • Share Acquisition: On February 17, 2026, Great Point Partners purchased 70,000 shares of Apogee Therapeutics (APGE) for an estimated $4.41 million, indicating strong confidence in the company's future prospects.
  • Asset Value Increase: This transaction boosted the fund's quarter-end position value by $16.15 million, reflecting the dual impact of new share acquisitions and stock price appreciation, demonstrating the effectiveness of its biotechnology investment strategy.
  • Increased Ownership Stake: Apogee Therapeutics now represents 9.15% of the fund's reportable assets, making it the largest holding, which underscores the fund's trust in its biologic platform, particularly in the concentrated investment in immunology.
  • Strong Financial Position: As of February 17, 2026, APGE shares were priced at $69.64, up 100% over the past year, showcasing robust market performance and potential growth opportunities, which are likely to continue attracting investor interest.
NASDAQ.COM
6.5
02-25NASDAQ.COM
Great Point Partners Increases Apogee Holdings by 70,000 Shares
  • Share Increase: Great Point Partners increased its position in Apogee Therapeutics by 70,000 shares in Q4 2026, with an estimated transaction value of $4.41 million, reflecting confidence in the company's future prospects.
  • Market Value Growth: The fund's quarter-end position value rose by $16.15 million, demonstrating the dual impact of new share acquisitions and stock price appreciation, further solidifying its investment stance in the biotech sector.
  • Investment Concentration: Apogee has become the fund's largest holding, now accounting for approximately 9.15% of reportable assets, indicating its significance in the portfolio and a strong focus on the biopharmaceutical field.
  • Strong Financial Position: With $913 million in cash, Apogee's financial health appears robust, providing a runway into the second half of 2028, which mitigates financial risk and supports future R&D and market expansion.
Newsfilter
1.0
02-24Newsfilter
Apogee Therapeutics Announces Upcoming Conference Participation
  • Management Conference Schedule: Apogee Therapeutics will participate in a fireside chat at the TD Cowen 46th Annual Health Care Conference on March 3, 2026, showcasing its latest advancements in biotechnology, which is expected to attract investor interest.
  • Multiple Conference Participation: The management team will also attend the UBS Biotech Summit on March 9, 2026, and the Jefferies Biotech on the Beach Summit on March 10, 2026, further enhancing the company's visibility and investor relations in the biotech sector.
  • Product Development Outlook: Apogee is advancing its antibody programs, particularly Zumilokibart (APG777) for Atopic Dermatitis (AD) and asthma, aiming to fill gaps in existing therapies and meet market demand.
  • Market Positioning and Goals: The company is committed to achieving best-in-class efficacy through monotherapies and combinations targeting four validated indications, striving to lead in the immunology and inflammation market and enhance patient treatment experiences.
Fool
6.5
02-22Fool
Perceptive Advisors Increases Stake in Apogee Therapeutics
  • Share Increase: On February 17, 2026, Perceptive Advisors disclosed a purchase of 978,662 shares of Apogee Therapeutics, with an estimated transaction value of $61.64 million, indicating strong confidence in the company.
  • Stake Proportion Rise: Following this acquisition, Perceptive Advisors' total holdings in Apogee reached 2,330,651 shares, representing 3.14% of its 13F AUM, reflecting ongoing interest in the biotech sector.
  • Outstanding Stock Performance: As of February 17, 2026, Apogee's shares were priced at $69.64, up 99.4% over the past year, significantly outperforming the S&P 500 by 78.67 percentage points, showcasing market optimism for its future growth.
  • Positive Financial Outlook: Apogee anticipates fiscal 2026 sales of approximately $1.39 billion, with adjusted EPS between $3.40 and $3.50, indicating potential in clinical development and commercialization, attracting long-term investor interest.
Wall Street analysts forecast APGE stock price to rise
15 Analyst Rating
Wall Street analysts forecast APGE stock price to rise
13 Buy
2 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
83.00
Averages
105.67
High
137.00
Current: 0.000
sliders
Low
83.00
Averages
105.67
High
137.00
Citi
Buy
maintain
$95
AI Analysis
2026-03-05
Reason
Citi
Price Target
$95
AI Analysis
2026-03-05
maintain
Buy
Reason
Citi added an "upside 30-day catalyst watch" on shares of Apogee Therapeutics while keeping a Buy rating on the name with a $95 price target. The firm sees a positive risk/reward profile into Apogee's Phase 2a maintenance study data for zumilokibart in atopic dermatitis.
Wedbush
Outperform
maintain
$90 -> $95
2026-03-03
Reason
Wedbush
Price Target
$90 -> $95
2026-03-03
maintain
Outperform
Reason
Wedbush raised the firm's price target on Apogee Therapeutics to $95 from $90 and keeps an Outperform rating on the shares. The firm notes the company reported earnings and reiterated guidance to March data for 52-week maintenance data from the Phase 2 APEX study of zumilokibart in atopic dermatitis. Induction data will follow in Q2 2026 for the dose-ranging portion of the trial, which should build on earlier results showing an exposure-response relationship. Wedbush expects Apogee will proceed to Phase 3 trials in the second half of 2026. Additional upside is possible from APG279 in the second half of 2026, the firm adds.
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Valuation Metrics

The current forward P/E ratio for Apogee Therapeutics Inc (APGE.O) is -17.23, compared to its 5-year average forward P/E of -12.33. For a more detailed relative valuation and DCF analysis to assess Apogee Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-12.33
Current PE
-17.23
Overvalued PE
-7.93
Undervalued PE
-16.74

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-6.73
Current EV/EBITDA
-13.68
Overvalued EV/EBITDA
-2.10
Undervalued EV/EBITDA
-11.36

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

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Whales Holding APGE

P
Paradigm Biocapital Advisors LP
Holding
APGE
+9.28%
3M Return
D
Driehaus Capital Management LLC
Holding
APGE
+8.18%
3M Return
V
Vestal Point Capital, LP
Holding
APGE
+6.94%
3M Return
P
Perceptive Advisors LLC
Holding
APGE
+6.14%
3M Return
V
VR Management, LLC
Holding
APGE
+6.00%
3M Return
F
Fairmount Funds Management LLC
Holding
APGE
+5.89%
3M Return

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Frequently Asked Questions

What is Apogee Therapeutics Inc (APGE) stock price today?

The current price of APGE is 74.68 USD — it has decreased -0.92

What is Apogee Therapeutics Inc (APGE)'s business?

Apogee Therapeutics, Inc. is a clinical-stage biotechnology company. The Company is advancing novel biologics with the potential for differentiated efficacy and dosing in the inflammatory and immunology (I&I) markets, including for the treatment of atopic dermatitis (AD), asthma, eosinophilic esophagitis (EoE), chronic obstructive pulmonary disease (COPD), and other I&I indications. APG777, the Company’s most advanced program, is being initially developed for the treatment of AD. With four validated targets in its portfolio, it is seeking to achieve efficacy and dosing through monotherapies and combinations of its novel antibodies. Its most advanced programs are APG777, APG990, APG333, and APG808. APG990 is an SQ extended half-life mAb that utilizes advanced antibody engineering to target OX40L. APG333 is a fully human mAb against thymic stromal lymphopoietin (TSLP). APG808 is an SQ extended half-life mAb targeting IL-4Rα. APG279 is for the dual inhibition of OX40L and IL-13.

What is the price predicton of APGE Stock?

Wall Street analysts forecast APGE stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for APGE is105.67 USD with a low forecast of 83.00 USD and a high forecast of 137.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Apogee Therapeutics Inc (APGE)'s revenue for the last quarter?

Apogee Therapeutics Inc revenue for the last quarter amounts to -78.06M USD, increased 2.87

What is Apogee Therapeutics Inc (APGE)'s earnings per share (EPS) for the last quarter?

Apogee Therapeutics Inc. EPS for the last quarter amounts to -62751000.00 USD, decreased

How many employees does Apogee Therapeutics Inc (APGE). have?

Apogee Therapeutics Inc (APGE) has 261000 emplpoyees as of March 11 2026.

What is Apogee Therapeutics Inc (APGE) market cap?

Today APGE has the market capitalization of 5.24B USD.