
ALXO
ALX Oncology Holdings Inc
- Overview
- Forecast
- Valuation
- Earnings

Line
|

Candle
1D
5D
1M
3M
6M
YTD
1Y
5Y
High
0.540
Open
0.540
VWAP
0.51
Vol
221.19K
Mkt Cap
28.12M
Low
0.5081
Amount
113.49K
EV/EBITDA(TTM)
--
Total Shares
52.10M
EV
-56.57M
EV/OCF(TTM)
--
P/S(TTM)
--
ALX Oncology Holdings Inc. is a clinical-stage immuno-oncology company focused on helping patients fight cancer by developing therapies that block the CD47 immune checkpoint inhibitor and bridge the innate and adaptive immune system. Its product candidate, evorpacept, is a CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated, proprietary Fc domain. It is engaged in focusing on combining evorpacept with anti-cancer antibodies, ADCs, and PD-1/PD-L1 immune checkpoint inhibitors. Cancer cells leverage CD47, a cell surface protein, as a don’t eat me signal to evade macrophage phagocytosis or as a don't activate T-cells signal that prevents activation of T-cells by dendritic cells. It focuses on combining evorpacept with anti-cancer antibodies, ADCs, and PD-1/PD-L1 immune checkpoint inhibitors. It also has a preclinical program focused on developing ALTA-002, a SIRPa TRAAC that offers ways to engage the innate and adaptive immune response to cancer.
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5 Analyst Rating

327.59% Upside
Wall Street analysts forecast ALXO stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ALXO is 2.25 USD with a low forecast of 1.00 USD and a high forecast of 3.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
4 Buy
1 Hold
0 Sell
Strong Buy

327.59% Upside
Current: 0.526

Low
1.00
Averages
2.25
High
3.00

327.59% Upside
Current: 0.526

Low
1.00
Averages
2.25
High
3.00
UBS
Buy
downgrade
$1
2025-05-21
Reason
UBS
Price Target
$1
2025-05-21
downgrade
Buy
Reason
UBS lowered the firm's price target on ALX Oncology to $1 from $1.20 and keeps a Buy rating on the shares.
H.C. Wainwright
Buy
downgrade
$5 -> $2
2025-05-09
Reason
H.C. Wainwright
Price Target
$5 -> $2
2025-05-09
downgrade
Buy
Reason
H.C. Wainwright lowered the firm's price target on ALX Oncology to $2 from $5 and keeps a Buy rating on the shares. The company announced its decision to discontinue the development of evorpacept in gastric and gastroesophageal cancers based on the FDA's feedback, the analyst tells investors in a research note.
HC Wainwright & Co.
Swayampakula Ramakanth
Strong Buy
Reiterates
$5
2025-03-07
Reason
HC Wainwright & Co.
Swayampakula Ramakanth
Price Target
$5
2025-03-07
Reiterates
Strong Buy
Reason
Stifel
Bradley Canino
Hold
Maintains
$3 → $1.5
2025-03-07
Reason
Stifel
Bradley Canino
Price Target
$3 → $1.5
2025-03-07
Maintains
Hold
Reason
Stifel lowered the firm's price target on ALX Oncology to $1.50 from $3 and keeps a Hold rating on the shares. Following a R&D day and the company's Q4 report, the firm updated its model for the quarter, restructuring, and updated cash guidance, but has reduced its odds of success and confidence in gastric cancer and awaits proof of concept data in additional tumor type regimens.
Jefferies
Michael Yee
Hold
to
Strong Buy
Upgrades
$2 → $3
2025-03-06
Reason
Jefferies
Michael Yee
Price Target
$2 → $3
2025-03-06
Upgrades
Hold
to
Strong Buy
Reason
Piper Sandler
Christopher Raymond
Buy
Maintains
$8 → $9
2025-03-06
Reason
Piper Sandler
Christopher Raymond
Price Target
$8 → $9
2025-03-06
Maintains
Buy
Reason
Piper Sandler raised the firm's price target on ALX Oncology to $9 from $8 and keeps an Overweight rating on the shares following the company's R&D Day, where management detailed a more focused evorpacept development and commercialization path. In the short term, the firm is awaiting ASPEN-03/04 data in HNSCC and engagement with the FDA to determine the path forward in gastric/GEJ cancer, which could potentiate two accelerated approval filings. New was the announcement of two expansions into HER2+ breast cancer and EGFR+ CRC, where based on previous signals of efficacy and assuming ALX carefully controls the trial enrollment and design, Piper feels positively about these opportunities. Combined with a novel ADC and trimmed expenses, the firm likes the setup here.
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Valuation Metrics
The current forward P/E ratio for ALX Oncology Holdings Inc (ALXO.O) is -0.32, compared to its 5-year average forward P/E of -10.42. For a more detailed relative valuation and DCF analysis to assess ALX Oncology Holdings Inc 's fair value, click here.
Forward PE
The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.

N/A
5Y Average PE
-10.42
Current PE
-0.32
Overvalued PE
3.15
Undervalued PE
-24.00
Forward EV/EBITDA
The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.

N/A
5Y Average EV/EBITDA
-8.18
Current EV/EBITDA
0.73
Overvalued EV/EBITDA
4.44
Undervalued EV/EBITDA
-20.80
Forward PS
The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.

N/A
5Y Average PS
-2183.05
Current PS
0.00
Overvalued PS
13334.68
Undervalued PS
-17700.77
Financials
Annual
Quarterly
FY2025Q1
N/A
Total Revenue
FY2025Q1
YoY :
-15.74%
-31.82M
Operating Profit
FY2025Q1
YoY :
-13.57%
-30.75M
Net Income after Tax
FY2025Q1
YoY :
-18.31%
-0.58
EPS - Diluted
FY2025Q1
YoY :
-35.06%
-24.72M
Free Cash Flow
FY2025Q1
N/A
Gross Profit Margin - %
FY2025Q1
N/A
FCF Margin - %
FY2025Q1
N/A
Net Margin - %
Trading Trends
Insider
Insiders are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
1.6K
USD
2
3-6
Months
4.6K
USD
3
6-9
Months
23.3K
USD
3
0-12
Months
10.0K
USD
3
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Hedge Fund
Hedge Funds are Neutral. There are no significant trading trends over the last quarter.
Sold
0-3
Months
0.0
Volume
0
3-6
Months
48.8K
Volume
1
6-9
Months
147.0K
Volume
1
0-12
Months
0.0
Volume
0
Bought
0-3
0
0.0
Volume
Months
3-6
0
0.0
Volume
Months
6-9
0
0.0
Volume
Months
0-12
0
0.0
Volume
Months
Congress Trading
Congress are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Insider
Insiders are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
1.6K
USD
2
3-6
Months
4.6K
USD
3
6-9
Months
23.3K
USD
3
0-12
Months
10.0K
USD
3
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
ALXO News & Events
Events Timeline
2025-05-20 (ET)
2025-05-20
08:10:29
ALX Oncology highlights preclinical data, development plans for ALX2004

2025-05-08 (ET)
2025-05-08
08:33:20
ALX Oncology reports Q1 EPS (58c) vs (71c) last year

2025-04-25 (ET)
2025-04-25
13:13:04
ALX Oncology reports 'encouraging' final results from Phase 1 evorpacept trial

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News
1.0
05-30NewsfilterALX Oncology to Present at the Jefferies 2025 Global Healthcare Conference
6.0
05-21BenzingaUBS Maintains Buy on ALX Oncology Holdings, Lowers Price Target to $1
9.0
05-20NewsfilterALX Oncology Highlights Differentiated Design, Preclinical Data and Development Plans for EGFR-Targeted ADC, ALX2004, in R&D Webcast Event
Sign Up For More News
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FAQ

What is ALX Oncology Holdings Inc (ALXO) stock price today?
The current price of ALXO is 0.5262 USD — it has decreased -2.59 % in the last trading day.

What is ALX Oncology Holdings Inc (ALXO)'s business?

What is the price predicton of ALXO Stock?

What is ALX Oncology Holdings Inc (ALXO)'s revenue for the last quarter?

What is ALX Oncology Holdings Inc (ALXO)'s earnings per share (EPS) for the last quarter?

What changes have occurred in the market's expectations for ALX Oncology Holdings Inc (ALXO)'s fundamentals?

How many employees does ALX Oncology Holdings Inc (ALXO). have?
