VolitionRx Releases Manuscript Showcasing New Cancer Biomarkers for Liquid Biopsy
VolitionRx announces preprint availability of a new manuscript entitled "Direct analysis of transcription factor protected cfDNA in plasma by ChIP-seq: Measurement of altered CTCF binding in cancer is a novel biomarker for liquid biopsy." This paper showcases both a new method, Capture-Seq, and new biomarkers for the detection of cancer. Volition has achieved 180-fold enrichment through its focus on chromosome fragments. Dr Jake Micallef, Chief Scientific Officer, Volition commented: "This is, I believe, a world-first breakthrough - it is the first time that transcription factor-bound DNA has been physically separated from the massive amounts of background DNA in the blood, and could, in my opinion, represent the biggest scientific breakthrough in cancer testing in recent years."
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- Voluntary Delisting Decision: Venus Concept has decided to voluntarily delist from NASDAQ, with the last trading day expected on February 6, 2026, aiming to reduce compliance costs to support the company's turnaround plan.
- Compliance Cost Consideration: The Board of Directors concluded that the resources required to continue SEC reporting obligations outweigh the benefits of NASDAQ listing, making this strategic decision to utilize resources more effectively.
- Next Steps Arrangement: The company plans to file Form 25 with the SEC on January 30, 2026, followed by Form 15 on February 9, 2026, which will immediately suspend its periodic reporting obligations, further streamlining operational processes.
- Commitment to Long-Term Financial Success: CEO Rajiv De Silva stated that this move will assist the company in collaborating with Madryn Asset Management to drive sustained long-term financial success.
- Significant Market Opportunity: VolitionRx's Nu.Q® Vet cancer detection tool has a total addressable market of approximately $100 million in the U.S., Europe, and Japan, which could rise to nearly $150 million with the inclusion of China, indicating vast potential in the global pet health sector.
- Detection Technology Promotion: By partnering with new centralized laboratories, VolitionRx integrates the Nu.Q® Canine Cancer Test into annual checkups and senior wellness exams, enabling veterinarians to detect cancer earlier, thus assisting pet owners in making timely treatment decisions and enhancing the quality of veterinary care.
- International Expansion: This expansion not only strengthens Volition's market presence in the U.S. and Asia but also enhances its competitiveness in the global early cancer detection market for pets through collaborations with established laboratories, further solidifying its industry leadership.
- Strategic Development Direction: VolitionRx is committed to improving the quality of life for humans and animals through early detection and disease monitoring, and this technology rollout aligns with its overall strategy aimed at driving long-term growth through innovation.
- Significant Market Opportunity: VolitionRx's Nu.Q® Vet cancer test presents a total addressable market of approximately $100 million in the U.S. and Europe, potentially rising to nearly $150 million with the inclusion of China, highlighting the company's growth potential in pet health.
- Laboratory Partnership Expansion: Starting February 2026, Midwest Veterinary Laboratory will offer the Nu.Q® Vet cancer test across all 50 states in the U.S., while Bioguard will provide the test through its Animal Health Diagnostic Center in Taiwan and China, significantly enhancing product accessibility.
- Early Detection Benefits: By incorporating the Nu.Q® canine cancer test into annual check-ups, veterinarians can detect cancer earlier, enabling pet owners to make timely, informed decisions about cancer care, thereby improving survival rates and quality of life for pets.
- Commitment to Technological Innovation: VolitionRx is dedicated to advancing health outcomes through its innovative blood testing technology, emphasizing its strategic importance in early disease detection and monitoring, which further solidifies its leadership position in the biotechnology sector.
- Industry Symposium Sponsorship: VolitionRx sponsors the Veterinary Meeting and Expo (VMX 2026) in Orlando, Florida, expected to attract around 20,000 veterinary professionals, enhancing brand visibility and facilitating engagement with industry experts.
- Cancer Detection Promotion: Dr. Sue Ettinger will present the Nu.Q® Vet Cancer Test at the conference, emphasizing its application in early cancer detection, enabling veterinarians to identify cancer sooner during annual check-ups, thus improving pet owners' decision-making capabilities.
- Market Opportunity Capture: By showcasing the Nu.Q® Test, VolitionRx not only demonstrates its innovative capabilities in veterinary diagnostics but also potentially drives future revenue growth by increasing market acceptance, further solidifying its market position.
- R&D Strategic Layout: VolitionRx is committed to enhancing early detection capabilities for cancer and other diseases through simple, cost-effective blood testing technologies, aiming to improve the quality of life for both animals and humans, showcasing its long-term development potential in the life sciences sector.
- Industry Symposium Sponsorship: VolitionRx sponsors the VMX 2026 veterinary conference in Orlando, Florida, expected to attract around 20,000 veterinary professionals, showcasing the potential of its Nu.Q® Vet Cancer Test and enhancing brand visibility.
- Expert Presentation: Renowned veterinary oncologist Dr. Sue Ettinger will present on January 19 how to utilize the Nu.Q® Vet Cancer Test in practice, aiding veterinarians in earlier cancer detection, thereby improving treatment decisions and outcomes for pets.
- Market Opportunity: By incorporating the Nu.Q® Canine Cancer Test into annual checkups and senior wellness exams, VolitionRx aims to enhance veterinarians' cancer detection capabilities, driving growth in the veterinary diagnostics market.
- Booth Showcase: The Volition Veterinary Diagnostics Development team will showcase its innovative products at booth 2243, leveraging this opportunity to engage with industry partners, further expanding market share and enhancing customer relationships.

- Financing Agreement Update: VolitionRx has entered into an amended securities purchase agreement with Lind Global Asset Management to secure $2 million in funding in exchange for a $2.4 million convertible promissory note, enhancing the company's liquidity.
- Equity Purchase Rights: The agreement includes a five-year warrant allowing the investor to purchase up to 7,000,350 shares at $0.5714 each, potentially increasing the investor's returns significantly.
- Repayment Structure: The 2026 Note will be repaid in 18 monthly installments of $133,333, with the option to pay in cash or stock, providing flexibility that may alleviate financial pressure on the company.
- Registration Statement Requirement: Under the agreement, VolitionRx must file a registration statement within 30 days covering all shares issued upon conversion of the Note or exercise of the Warrant, ensuring investor rights are protected.






