TAGRISSO® (osimertinib) combined with chemotherapy shows nearly four years of median overall survival, marking the longest benefit recorded in a global Phase III trial for advanced lung cancer with EGFR mutations.
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Sep 07 2025
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Source: Yahoo Finance
FLAURA2 Trial Results: The final overall survival analysis from the FLAURA2 Phase III trial indicates that AstraZeneca's TAGRISSO (osimertinib) combined with chemotherapy significantly improves overall survival in patients with EGFR-mutated non-small cell lung cancer compared to TAGRISSO alone, with a median survival of 47.5 months versus 37.6 months.
Standard of Care: The results support TAGRISSO as the first-line standard of care for advanced EGFR-mutated lung cancer, providing physicians with effective treatment options tailored to individual patient needs, while maintaining manageable safety profiles.
Analyst Views on AZN
Wall Street analysts forecast AZN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for AZN is 102.75 USD with a low forecast of 95.00 USD and a high forecast of 108.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
5 Analyst Rating
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 91.690
Low
95.00
Averages
102.75
High
108.00
Current: 91.690
Low
95.00
Averages
102.75
High
108.00
About AZN
AstraZeneca PLC is a United Kingdom-based science-led biopharmaceutical company. The Company focuses on the discovery, development, and commercialization of prescription medicines. The Company operates across therapy areas, including Oncology; Cardiovascular, Renal and Metabolism (CVRM); Respiratory and Immunology (R&I); Vaccines and Immune Therapies (V&I), and Rare Disease. In the Oncology area, its key products include Tagrisso, Imfinzi, Calquence, Lynparza, and Enhertu. The key products of CVRM area include Farxiga/Forxiga, Brilinta/Brilique, Crestor, and Lokelma. In the R&I area, the key products are Symbicort, Fasenra, Breztri/Trixeo, and Tezspire. In the V&I Therapies area, the products are Beyfortus and FluMist. The products in the Rare Disease area are Ultomiris, Soliris, Strensiq, and Koselugo. It has about 191 projects in its development pipeline, including 19 new molecular entities (NMEs) in the late-stage pipeline. The Company distributes its products in over 125 countries.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
