Lisata Therapeutics showcases data on iRGD cyclic peptide product candidate
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Nov 04 2025
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Lisata Therapeutics Presentation: Lisata Therapeutics showcased preclinical data at the 16th Annual World ADC San Diego Conference, highlighting the effectiveness of their iRGD cyclic peptide product candidate, certepetide, in enhancing antibody-drug conjugate (ADC) technology.
Impact of Certepetide: Catalent's presentation revealed that certepetide, used as a non-cytotoxic ADC payload, improved efficacy and distribution of cytotoxic agents within tumors, reinforcing its potential in therapeutic applications.
Expert Commentary: Kristen Buck, Lisata's Executive Vice President, emphasized the encouraging data supporting certepetide's ability to enhance targeting and effectiveness of therapeutic agents, particularly in ADCs.
Strategic Partnership: The results strengthen Lisata's belief in the value of their partnership with Catalent and their strategy to leverage certepetide's unique mechanism to improve therapeutic outcomes across various treatment modalities.
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Analyst Views on LSTA
About LSTA
Lisata Therapeutics, Inc. is a clinical-stage pharmaceutical company engaged in the discovery, development and commercialization of therapies for the treatment of advanced solid tumors and other major diseases. The Company’s cyclic peptide product candidate, certepetide, is an investigational drug designed to activate a novel uptake pathway that allows co-administered or tethered anti-cancer drugs to selectively target and penetrate solid tumors more effectively. Certepetide actuates this active transport system in a tumor-specific manner, resulting in systemically co-administered anti-cancer drugs penetrating and accumulating in the tumor, while normal tissues are expected to remain unaffected. The Company’s investigational drug candidate from the CendR Platform, certepetide, holds broader potential to be combined as a co-administration treatment with an array of anti-cancer and diagnostic agents to benefit solid tumor cancer patients.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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Monteverde Law Firm Investigates Multiple Acquisition Cases
- Shareholder Compensation Investigation: Monteverde & Associates is investigating the acquisition of Penumbra, Inc. by Boston Scientific Corporation, where shareholders are expected to receive either $374 in cash or 3.8721 shares of Boston Scientific, highlighting a commitment to shareholder rights.
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